Fungi and products thereof
US-9222096-B2 · Dec 29, 2015 · US
US2015225744A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2015225744-A1 |
| Application number | US-201514625487-A |
| Country | US |
| Kind code | A1 |
| Filing date | Feb 18, 2015 |
| Priority date | Oct 7, 2011 |
| Publication date | Aug 13, 2015 |
| Grant date | — |
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The invention provides for methods for the production of mevalonate, isoprene, isoprenoid precursor molecules, and/or isoprenoids in cells via the heterologous expression of phosphoketolase enzymes.
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1 . Recombinant cells capable of producing of isoprene, wherein the cells comprise one or more heterologous nucleic acids encoding a polypeptide having phosphoketolase activity and (i) one or more nucleic acids encoding one or more polypeptides of the complete MVA pathway and (ii) a heterologous nucleic acid encoding an isoprene synthase polypeptide, wherein culturing of said recombinant cells in a suitable media provides for the production of isoprene. 2 - 15 . (canceled)…
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