Leucine zipper variant and use thereof

US2015094271A1 · US · A1

Patent metadata
FieldValue
Publication numberUS-2015094271-A1
Application numberUS-201414502088-A
CountryUS
Kind codeA1
Filing dateSep 30, 2014
Priority dateSep 30, 2013
Publication dateApr 2, 2015
Grant date

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Abstract

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A leucine zipper variant, a polynucleotide encoding the leucine zipper variant, a method of preparing a leucine zipper variant, a method of inhibiting HDM2- and/or HDMX using the leucine zipper variant, and a method of the prevention and/or treatment of cancer using the leucine zipper variant.

First claim

Opening claim text (preview).

What is claimed is: 1 . A leucine zipper polypeptide variant comprising SEQ ID NO: 1 with an amino acid substitution at one or more of positions 10, 14, 15, 18 and 21. 2 . The leucine zipper polypeptide variant of claim 1 , wherein the substitution is selected from the group consisting of: (a) substitution of glutamic acid (E) with glycine (G) at position 10; (b) substitution of lysine (K) with serine (S) at position 15; (c substitution of serine (S) w…

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What does patent US2015094271A1 cover?
A leucine zipper variant, a polynucleotide encoding the leucine zipper variant, a method of preparing a leucine zipper variant, a method of inhibiting HDM2- and/or HDMX using the leucine zipper variant, and a method of the prevention and/or treatment of cancer using the leucine zipper variant.
Who is the assignee on this patent?
Samsung Electronics Co Ltd
What technology area does this patent fall under?
Primary CPC classification C12N7/00. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Thu Apr 02 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).