Treatment of protein aggregation myopathic and neurodegenerative diseases by parenteral administration of trehalose
US-2024009113-A1 · Jan 11, 2024 · US
Inositol and trehalose derivatives and pharmaceutical compositions for treating neurodegenerative diseases comprising the same
US2015025035A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2015025035-A1 |
| Application number | US-201414509175-A |
| Country | US |
| Kind code | A1 |
| Filing date | Oct 8, 2014 |
| Priority date | Jul 22, 2008 |
| Publication date | Jan 22, 2015 |
| Grant date | — |
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Abstract
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The invented inositol and trehalose derivatives, prepared by introducing multiple units of the guanidine group to the backbone molecules, show excellent blood-brain barrier permeability, and accordingly, it can be easily transported to the brain tissues and utilized for the treatment of neurodegenerative diseases such as Alzheimer's disease and Huntington's disease.
First claim
Opening claim text (preview).
What is claimed are: 1 . A trehalose compound of Formula (3) or a salt thereof: wherein, R is n being an integer in the range of 1 to 12; and R 1 is hydrogen, R, alkyl or —COR′, R′ being hydrogen, alkyl, aminoalkyl, arylalkyl, cycloalkyl, heteroa…
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Human Necessities · mapped topic
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
- C07H3/04Primary
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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Frequently asked questions
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- What does patent US2015025035A1 cover?
- The invented inositol and trehalose derivatives, prepared by introducing multiple units of the guanidine group to the backbone molecules, show excellent blood-brain barrier permeability, and accordingly, it can be easily transported to the brain tissues and utilized for the treatment of neurodegenerative diseases such as Alzheimer's disease and Huntington's disease.
- Who is the assignee on this patent?
- Postech Acad Ind Found
- What technology area does this patent fall under?
- Primary CPC classification C07H3/04. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Thu Jan 22 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).