Neurostimulation method and system for active emulation of passive discharge in presence of mri/emi interference
US-2021178162-A1 · Jun 17, 2021 · US
US12589247B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12589247-B2 |
| Application number | US-202318295828-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 4, 2023 |
| Priority date | Feb 15, 2018 |
| Publication date | Mar 31, 2026 |
| Grant date | Mar 31, 2026 |
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This disclosure relates to a device for applying a neural stimulus. A battery supplies electrical energy at a battery voltage and an electrode applies the electrical energy to neural tissue. A circuit measures the nervous response of the tissue and a voltage converter receives the electrical energy from the battery and controls a voltage applied to the electrode based on the measured nervous response of the tissue. This direct voltage control is energy efficient because losses across a typical current mirror are avoided. Further, the control based on the measured nervous response leads to automatic compensation of impedance variation due to in-growth or change in posture. As a result, the stimulation results in a desired neural response.
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The invention claimed is: 1 . A device for applying a neural stimulus comprising: a battery to supply electrical energy at a battery voltage; an electrode to apply the electrical energy to neural tissue; a circuit to measure a nervous response of the neural tissue; a switched mode voltage to current converter to receive the electrical energy from the battery and to control a current applied to the electrode; and a controller configured to control switching of the switched mode voltage to current converter based on the measured nervous response of the neural tissue. 2 . The device of claim 1 , wherein the controller is further configured to control the switching based on the battery voltage. 3 . The device of claim 1 , wherein the controller is further configured to control the switching based on an electrode voltage. 4 . The device of claim 1 , wherein the controller is further configured to control the switching based on a predetermined stimulation intensity. 5 . The device of claim 1 , wherein the controller comprises a pulse generator to generate a pulse signal to control the switching. 6 . The device of claim 5 , wherein the pulse generator comprises a voltage controlled oscillator to generate the pulse signal. 7 . The device of claim 5 , wherein the controller comprises a voltage controlled oscillator to control a frequency of the pulse signal based on a desired level of stimulation and a tissue voltage and a voltage controlled delay to control a time period for which a switch connects an inductance to the battery at each oscillation based on the battery voltage. 8 . The device of claim 5 wherein the pulse signal is periodic and controlling the switching comprises suppressing pulses that turn a switch on to set the amount of energy provided by an inductance. 9 . The device of claim 1 , wherein the controller comprises a voltage controlled delay controlled by the battery voltage to control the switching. 10 . The device of claim 9 wherein the voltage controlled delay is connected to a switch to disconnect an inductance from the battery after a delay controlled by the battery voltage. 11 . The device of claim 9 , wherein the voltage controlled delay is connected to a switch to disconnect an inductance from the battery after a delay controlled by a tissue voltage. 12 . The device of claim 9 , wherein the voltage controlled delay is connected to a switch to disconnect an inductance from the battery after a delay controlled by a desired level of stimulation intensity. 13 . The device of claim 1 , wherein the controller is a digital processor. 14 . The device of claim 13 , wherein the device comprises an analog-to-digital converter to provide a digital signal indicative of the measured nervous response of the neural tissue to the digital processor. 15 . A device for applying a neural stimulus comprising: a battery to supply electrical energy at a battery voltage; an electrode to apply the electrical energy to neural tissue; a circuit to measure a nervous response of the neural tissue; and a pulse generator to generate stimulation current pulses at a pulse length and to adjust the pulse length based on the measured nervous response of the neural tissue; wherein the circuit to measure the nervous response of the neural tissue comprises a template and the circuit is configured to shift the template in time relative to the stimulation current pulses based on the pulse length so as to measure the nervous response of the neural tissue. 16 . The device of claim 15 , wherein the circuit comprises a look-up table storing delay values for the template for each of multiple pulse width values.
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