Oxazoline compound, synthesis method therefor and application thereof

Patent metadata

Field	Value
Publication number	US-12588678-B2
Application number	US-202017621900-A
Country	US
Kind code	B2
Filing date	Sep 24, 2020
Priority date	Sep 24, 2019
Publication date	Mar 31, 2026
Grant date	Mar 31, 2026

Abstract

Disclosed are an oxazoline compound, a synthesis method therefor and an application thereof. The oxazoline compound has a structure represented by formula (I), wherein in the formula (I), R is selected from groups represented by formula (I-1), formula (I-2), and formula (I-3), where an oxazoline derivative having a novel molecular structure is obtained by introducing a nitrogen heterocycle, an ether bond or a sulfonate structure into the oxazoline compound. The oxazoline derivative is useful in the field of agricultural protection, and has higher acaricidal activity than etoxazole, can inhibit the synthesis of chitin from mites, and can effectively control the embryogenesis and development of eggs of Tetranychus cinnabarinus , as well as the ecdysis process from larvae to adults, and therefore has a significant effect in killing mite eggs and larvae.

First claim

The invention claimed is:

1 . An oxazoline compound which is characterized by having a structure shown in a formula (I),

wherein, in the formula (I), R is selected from a group shown in a formula (I-1);

in the formula (I-1), the nitrogen-containing heterocyclic ring represented by R 1 is selected from substituted or unsubstituted five-membered to ten-membered single heterocyclic group, substituted or unsubstituted eight-membered to twelve-membered condensed bicyclic group, and the optional substituent groups on R 1 are each independently selected from at least one of halogen, C 1-10 alkyl, C 1-10 alkoxy and C 2-10 acyl.

2 . A method for controlling phytophagous mites, comprising:
applying a mite-controlling effective amount of the oxazoline compound of claim 1 to a site or plant in need thereof.

3 . The oxazoline compound of claim 1 , wherein the oxazoline compound is selected from any one of the following compounds:

4 . A method for controlling phytophagous mites, comprising: applying a mite-controlling effective amount of an oxazoline compound of claim 3 to a site or plant in need thereof.

Assignees

• Univ Nankai

Inventors

• Wang Qingmin
• Liu Yuxiu
• Wang Ziwen
• Song Hongjian
• Li Yongqiang
• Chen Shilin
• Zhang Yu

Classifications

• C07D413/10

  linked by a carbon chain containing aromatic rings · CPC title

• C07D263/14

  with radicals substituted by oxygen atoms · CPC title

• A01P7/02

  Acaricides · CPC title

• C07D413/12

  linked by a chain containing hetero atoms as chain links · CPC title

• A01N43/78

  1,3-Thiazoles; Hydrogenated 1,3-thiazoles · CPC title