Blood flow extraction image forming device, method of forming blood flow extraction image, and blood flow extraction image forming program

Patent metadata

Field	Value
Publication number	US-12586185-B2
Application number	US-202318211359-A
Country	US
Kind code	B2
Filing date	Jun 19, 2023
Priority date	Jun 29, 2022
Publication date	Mar 24, 2026
Grant date	Mar 24, 2026

Abstract

A correlation matrix calculation unit calculates a correlation matrix R zx for each data element of the frame data. A blood flow luminance image forming unit forms a blood flow extraction filter P k,N on the basis of an eigenvalue λ i of a rank equal to or lower than a first threshold rank, the eigenvalue being obtained by singular value decomposition on the correlation matrix R zx , and an eigenvector w i , w i H corresponding to the eigenvalue λi and applies the blood flow extraction filter P k,N to frame data F, therebyto forming a blood flow luminance image U k,N . A tissue image forming unit forms a tissue image including tissue components on the basis of a signal value of each data element forming the plurality of pieces of the frame data. A blood flow extraction image forming unit subtracts the tissue image from the blood flow luminance image U k, N , thereby forming a blood flow extraction image U out .

First claim

The invention claimed is:

1 . A blood flow extraction image forming device comprising one or more processors configured to perform a method for forming a blood flow extraction image, the method comprising:
acquiring a plurality of pieces of frame data for a plurality of frames, the plurality of pieces of the frame data being generated on the basis of a plurality of reception signals obtained by causing an ultrasonic probe that transmits and receives ultrasonic waves to and from a subject, to transmit ultrasonic waves to a same scanning plane a plurality of times and receive reflected waves of the ultrasonic waves from the subject and having signal values indicating signal intensity of the reflected waves; calculating a correlation matrix indicating a correlation between the signal values in the plurality of pieces of the frame data for each data element of the frame data corresponding to each pixel of an ultrasonic image formed based on the frame data; performing singular value decomposition on the correlation matrix to calculate a plurality of singular values whose ranks are defined in order of magnitude and a plurality of singular vectors corresponding to the singular values; forming a blood flow luminance image by applying, to the frame data, a blood flow extraction filter formed based on the singular value of a rank equal to or lower than a preset first threshold rank and the singular vector corresponding to the singular value; forming a tissue image on the basis of the signal value of each data element forming the plurality of pieces of the frame data; forming a blood flow extraction image by subtracting the tissue image from the blood flow luminance image; specifying a calculation target region including one or more data elements corresponding to tissue in the frame data, the correlation matrix being calculated in the method only for the calculation target region; acquiring high-rank extraction data including signal components of a rank higher than a second threshold rank, by performing singular value decomposition on the plurality of pieces of the frame data; thinning out some of data elements forming the high-rank extraction data; and setting thinned frame data as the calculation target region.

2 . The blood flow extraction image forming device according to claim 1 , wherein the tissue image is formed in the method by applying, to the frame data, a tissue extraction filter formed based on the singular value of a rank higher than the first threshold rank and the singular vector corresponding to the singular value.

3 . The blood flow extraction image forming device according to claim 1 , wherein the blood flow extraction image is formed by subtracting the tissue image multiplied by a coefficient from the blood flow luminance image.

4 . The blood flow extraction image forming device according to claim 3 , the method performed by the one or more processors further comprising:
determining the coefficient on the basis of input from a user.

5 . A blood flow extraction image forming device comprising one or more processors configured to perform a method for forming a blood flow extraction image, the method comprising:
acquiring a plurality of pieces of frame data for a plurality of frames, the plurality of pieces of the frame data being generated on the basis of a plurality of reception signals obtained by causing an ultrasonic probe that transmits and receives ultrasonic waves to and from a subject, to transmit ultrasonic waves to a same scanning plane a plurality of times and receive reflected waves of the ultrasonic waves from the subject and having signal values indicating signal intensity of the reflected waves; calculating a correlation matrix indicating a correlation between the signal values in the plurality of pieces of the frame data for each data element of the frame data corresponding to each pixel of an ultrasonic image formed based on the frame data; performing singular value decomposition on the correlation matrix to calculate a plurality of singular values whose ranks are defined in order of magnitude and a plurality of singular vectors corresponding to the singular values; forming a blood flow luminance image by applying, to the frame data, a blood flow extraction filter formed based on the singular value of a rank equal to or lower than a preset first threshold rank and the singular vector corresponding to the singular value; forming a tissue image on the basis of the signal value of each data element forming the plurality of pieces of the frame data; forming a blood flow extraction image by subtracting the tissue image from the blood flow luminance image; specifying a calculation target region including the data element corresponding to tissue in the frame data, the correlation matrix being calculated in the method only for the calculation target region; acquiring high-rank extraction data including signal components of a rank higher than a second threshold rank by performing singular value decomposition on the plurality of pieces of the frame data; and setting, as the calculation target region, a set of the data elements having the signal values equal to or larger than a threshold signal value among the plurality of data elements forming the high-rank extraction data.

6 . A blood flow extraction image forming device comprising one or more processors configured to perform a method for forming a blood flow extraction image, the method performed by the one or more processors comprising:
acquiring a plurality of pieces of frame data for a plurality of frames, the plurality of pieces of the frame data being generated on the basis of a plurality of reception signals obtained by causing an ultrasonic probe that transmits and receives ultrasonic waves to and from a subject, to transmit ultrasonic waves to a same scanning plane a plurality of times and receive reflected waves of the ultrasonic waves from the subject and having signal values indicating signal intensity of the reflected waves; specifying, in the frame data, a calculation target region including a data element of the frame data corresponding to each pixel of an ultrasonic image formed based on the frame data, the data element corresponding to tissue; calculating a correlation matrix indicating a correlation between the signal values in the plurality of pieces of the frame data for each data element forming the frame data, the correlation matrix being calculated only for the calculation target region; performing singular value decomposition on the correlation matrix to calculate a plurality of singular values whose ranks are defined in order of magnitude and a plurality of singular vectors corresponding to the singular values; forming a blood flow luminance image by applying, to the frame data, a blood flow extraction filter formed based on the singular value of a rank equal to or lower than a preset first threshold rank and the singular vector corresponding to the singular value; forming a tissue image by applying, to the frame data, a tissue extraction filter formed based on the singular value of a rank higher than the first threshold rank and the singular vector corresponding to the singular value; and forming a blood flow extraction image by subtracting the tissue image from the blood flow luminance image; acquiring high-rank extraction data including signal components of a rank higher than a second threshold rank, by performing singular value decomposition on the plurality of pieces of the frame data; thinning out some of data elements forming the high-rank extraction data; and setting thinned frame data as the calculation target region.

7 . A method of forming a blood flow extraction image, the method comprising:
a frame data acquisition step of acquiring a

Assignees

• Fujifilm Healthcare Corp
• Fujifilm Corp

Inventors

• Yoshikawa Hideki
• Fujita Kosuke
• Yamada Tetsuya

Classifications

• G06T2207/10132

  Ultrasound image · CPC title

• G06T2207/30104

  Vascular flow; Blood flow; Perfusion · CPC title

• A61B8/5223

  for extracting a diagnostic or physiological parameter from medical diagnostic data (for algorithms to analyse biomedical images G06T7/0012) · CPC title

• A61B8/0891

  for diagnosis of blood vessels · CPC title

• A61B8/5246

  combining images from the same or different imaging techniques, e.g. color Doppler and B-mode · CPC title