Systems and methods of monitoring autoregulation
US-2018014791-A1 · Jan 18, 2018 · US
US12575748B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12575748-B2 |
| Application number | US-202117484790-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 24, 2021 |
| Priority date | Mar 25, 2019 |
| Publication date | Mar 17, 2026 |
| Grant date | Mar 17, 2026 |
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A blood pressure-related information display device, for visualizing and displaying information relating to blood pressure surges, is provided with: a blood pressure surge detection unit which, from time series data of blood pressure which changes linked to the subject's pulse, detects a blood pressure surge on the basis of a preset determination standard; a bodily state input unit which, together with the time series data of blood pressure, inputs bodily state information which indicates the bodily state of the subject; an extraction unit which extracts a feature value of the blood pressure surge; a statistical processing unit which performs statistical processing of the extracted feature value of the blood pressure surge; a calculation unit which calculates a feature value of the subject's bodily state; a display processing unit which performs processing for displaying, on a display screen, the correlation between the feature value of the blood pressure surge which was subjected to statistical processing, and the feature value of the bodily state.
Opening claim text (preview).
The invention claimed is: 1 . A medical system that collects, processes and displays a correlation between blood pressure surge information and bodily state information of a subject which are obtained during a same predetermined sleep time period, the medical system comprising: a tonometry type sphygmomanometer configured to repeatedly measure a time-series data of blood pressure of the subject during the predetermined sleep time period of the subject; a bodily state sensor group configured to repeatedly measure and output the bodily state information of a bodily state of the subject during the predetermined sleep time period; and a processor programmed to: detect one or more blood pressure surges during the predetermined sleep time period of the subject based on predetermined determination criteria for the time-series data of blood pressure that changes in conjunction with a pulsation of the subject, input the bodily state information repeatedly taken during the predetermined sleep time period of the subject indicating the bodily state of the subject including at least one of an apnea condition and a hypopnea condition, along with the time-series data of the blood pressure, extract from the time-series data of blood pressure obtained during the predetermined sleep time period of the subject, a feature value of each of the blood pressure surges including at least one of: a surge fluctuation amount during a rising time from a start of the blood pressure surge to a peak point of the blood pressure surge; a rising surge rate; a surge fluctuation amount during a falling time from the peak point of the blood pressure surge to an end of the blood pressure surge; a falling surge rate; a surge area in the rising time or in the falling time; and a surge time span including a time span of the rising time and a time span of the falling time, perform statistical processing of the extracted feature values of the blood pressure surges, the statistical processing including at least one of an average, a standard deviation, a maximum value, a minimum value, and a quartile, of a plurality of the feature values of the blood pressure surges, wherein the processor selectively performs the statistical processing of the extracted feature values that occur during a detected apnea or hypopnea event in within the predetermined sleep time period; calculate a feature value of the bodily state of the subject from each input bodily state information obtained during the predetermined sleep time period of the subject, the feature value of the bodily state being at least one of: an apnea and hypopnea index measured per a predetermined time length; an average value of the apnea or hypopnea duration; an average value of a reduction amount of a percutaneous arterial oxygen saturation at a time of occurrence of the blood pressure surge; an average value of a reduction time of percutaneous arterial oxygen saturation; an average value of a bottom value of percutaneous arterial oxygen saturation; a variation average value of a heart rate or a pulse rate; an average value of a peak value of the heart rate or the pulse rate; and a statistical amount of a median, correlate, after each predetermined sleep time period, a numerical relationship between (i) the statistically processed feature values of the blood pressure surges and (ii) the calculated feature values of the bodily state obtained within the same predetermined sleep time period, and perform processing for displaying on a display screen, after each predetermined sleep time period, a correlation graph showing a series of correlations for different predetermined sleep time periods including a latest correlation result that is separately displayed from one or more correlation results obtained before the latest correlation result, wherein the processor is programmed to associate user-entered medication information with the latest correlation result, and perform a process of displaying an updated correlation graph to show the latest correlation result and the associated user-entered medication information. 2 . The system according to claim 1 , wherein the processor sets on the display screen a coordinate system in the correlation graph which is defined by a first axis representing the statistically processed feature values of the blood pressure surges and a second axis representing the calculated feature values of the bodily state. 3 . A medical method that collects, processes and displays a correlation between blood pressure surge information and bodily state information of a subject which are obtained during a same predetermined sleep time period, the method comprising: measuring repeatedly, by a tonometry type sphygmomanometer, a time-series data of blood pressure of the subject during the predetermined sleep time period of the subject; measuring repeatedly and outputting, by a bodily state sensor group, the bodily state information of a bodily state of the subject during the predetermined sleep time period; detecting, by a processor, one or more blood pressure surges during the predetermined sleep time period of the subject based on predetermined determination criteria for the time-series data of blood pressure that changes in conjunction with a pulsation of the subject; inputting, by the processor, the bodily state information repeatedly taken during the predetermined sleep time period of the subject indicating the bodily state of the subject including at least one of an apnea condition, and a hypopnea condition, along with the time-series data of the blood pressures; extracting, by the processor, from the time series data of blood pressure obtained during the predetermined sleep time period of the subject, a feature value of each of the blood pressure surges including at least one of: a surge fluctuation amount during a rising time from a start of the blood pressure surge to a peak point of the blood pressure surge; a rising surge rate; a surge fluctuation amount during a falling time from the peak point of the blood pressure surge to an end of the blood pressure surge; a falling surge rate; a surge area in the rising time or in the falling time; and a surge time span including a time span of the rising time and a time span of the falling time; performing, by the processor, statistical processing of the extracted feature values of the blood pressure surges, the statistical processing including at least one of an average, a standard deviation, a maximum value, a minimum value, and a quartile, of a plurality of the feature values of the blood pressure surges, wherein the statistical processing includes selectively performing the statistical processing on the extracted feature values that occur during a detected apnea or hypopnea event in within the predetermined sleep time period; calculating, by the processor, a feature value of a bodily state of the subject from each input bodily state information obtained during the predetermined sleep time period of the subject, the feature value of the bodily state being at least one of: an apnea and hypopnea index measured per a predetermined time length; an average value of the apnea or hypopnea duration; an average value of a reduction amount of a percutaneous arterial oxygen saturation at a time of occurrence of the blood pressure surge; an average value of a reduction time of percutaneous arterial oxygen saturation; an average value of a bottom value of percutaneous arterial oxygen saturation; a variation average value of a heart rate or a pulse rate; an average value of a peak value of the heart rate or the pulse rate; and a statistical amount of a median; correlating, by the processor, after each predetermined sleep time period, a numerical relationship between (i) the statistically processed feature values of the blood pressure surges and (ii) the calculated feature values of the b
Displaying an image simultaneously with additional graphical information, e.g. symbols, charts, function plots · CPC title
using correlation, e.g. template matching or determination of similarity · CPC title
Monitoring or testing the effects of treatment, e.g. of medication · CPC title
Sleep apnoea · CPC title
Sleep quality · CPC title
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