Ophthalmic system and method for clinical device using transcleral illumination with multiple points source

Patent metadata

Field	Value
Publication number	US-12575730-B2
Application number	US-201917312819-A
Country	US
Kind code	B2
Filing date	Dec 12, 2019
Priority date	Dec 12, 2018
Publication date	Mar 17, 2026
Grant date	Mar 17, 2026

Abstract

An ophthalmic illumination and imaging system with transscleral/transpalpebral illumination of the eye fundus comprises a light-delivering device with a plurality of emitting areas; each of the emitting areas being configured to be independently controllable and directed towards the sclera of the intended eye to measure, providing transscleral oblique illumination of the eye fundus; an active eye aberration correcting system; and an imaging system configured to create multiple images of the eye fundus on multiple imaging sensors.

First claim

The invention claimed is:

1 . An ophthalmic illumination and imaging system with transscleral/transpalpebral illumination of the eye fundus, the system comprising:
a light-delivering device with a plurality of emitting areas; each of the emitting areas being configured to be independently controllable and directed towards the sclera of the intended eye to measure, providing transscleral oblique illumination of the eye fundus; an active eye aberration correcting system; and wherein the system further comprises an imaging system configured to create multiple images of the eye fundus on multiple imaging sensors, said multiple sensor comprising a first retinal camera imaging the retina of the intended eye to measure with high resolution and a second retinal camera imaging said retina over a field of at least about 30°, wherein the system further comprises:
an active tracking system configured to track a movement of the eye fundus and configured to spatially stabilize at least one of the multiple eye fundus, wherein a measure of the movement of the eye is made using at least one of the multiple eye fundus images, wherein the correction of the eye movement is made using a 2-axis tip/tilt platform supporting the full wavefront corrector with an external rotation stage, or wherein the correction of the eye movement is made using a 2-axis tip/tilt platform supporting a mirror which does not include the wavefront corrector.

2 . The system according to claim 1 , wherein the retinal camera is configured to image the retina with a digital sampling smaller than 2 μm/pixel.

3 . The system according to 1 , wherein the retinal camera is configured to image the retina with a digital sampling of 20 μm/pixel.

4 . The system according to claim 1 , wherein the imaging system is configured to create multiple images of the eye fundus simultaneously on multiple imaging sensors.

5 . The system according to claim 1 , wherein the tracking system comprises a tracking sensor measuring the movement of the eye fundus and a tracking corrector configured to correct the at least one of the multiple images spatially stabilized for the movement.

6 . The system according to claim 1 , wherein the system further comprises
a sequential switch configured to sequentially turn on one of the plurality of emitter areas at a time and enable a corresponding sequence in time of the eye fundus images created by the imaging system.

7 . The system according to claim 1 , wherein the active the eye aberrations correcting system comprises a wavefront sensor and a wavefront corrector.

8 . The system according to claim 1 , wherein the multiple images are produced with the light-delivering device.

9 . The system according to claim 1 , wherein a correction of the movement of the eye is made by tilting a mirror located at an optically conjugated eye pupil plane.

10 . The system according to claim 1 , wherein the correction of the eye movement is made using the tilting ablility of the wavefront corrector used for the active correction of the eye aberrations.

11 . The system according to claim 1 , wherein multiple imaging paths making the multiple eye fundus images are separated thanks to a beam splitter or a dichroic mirror.

12 . The system according to claim 1 , wherein the light-delivering device contains a light diffuser.

13 . The system according to claim 12 , wherein the diffuser integrated in the light-delivering device is used to obtain a few millimeters wide spot on the sclera or skin surface.

14 . The system according to claim 12 , wherein the diffuser is moving to produce temporal averaging of the speckle noise.

15 . The system according to claim 1 , wherein a wavelength of the light delivering device is chosen in the transmission range of the sclera-choroid-skin approximately from 400 nm to 1200 nm.

16 . The system according to claim 1 , wherein the light delivering device comprises a plurality of elementary components such as light emitting diode, superluminescent diode, organic light emitting diode, optical fibers.

17 . The system according to claim 15 wherein individual emitting areas have a different temporal spectrum of emission from one to another.

18 . The system according to claim 15 , wherein individual emitting areas have a different angular spectrum of emission from one to another.

19 . The system according to claim 1 , further comprising a camera configured to record interference from one or several exit beams from the pupil and an additional reference beam extracted from the light-delivering device before entering the eye.

20 . The system according to claim 1 , wherein a non-uniform phase or absorption object is placed in a conjugated pupil plane to increase the phase contrast.

Assignees

• Ecole Polytechnique Fed Lausanne Epfl

Inventors

• Laforest Timothé
• Moser Christophe
• Kunzi Mathieu

Classifications

• A61B3/145

  by video means · CPC title

• A61B3/12

  for looking at the eye fundus, e.g. ophthalmoscopes (A61B3/13 takes precedence) · CPC title

• A61B3/113

  for determining or recording eye movement · CPC title

• A61B3/1225 Primary

  using coherent radiation · CPC title

• A61B3/0008 Primary

  provided with illuminating means (A61B3/117, A61B3/14 take precedence) · CPC title