Catheter system for implantation of prosthetic heart valves

Patent metadata

Field	Value
Publication number	US-12569336-B2
Application number	US-202218061853-A
Country	US
Kind code	B2
Filing date	Dec 5, 2022
Priority date	Jan 20, 2005
Publication date	Mar 10, 2026
Grant date	Mar 10, 2026

Abstract

The invention relates to a catheter for the transvascular implantation of prosthetic heart valves, in particular including self-expanding anchorage supports ( 10 ), which allow a minimally invasive implantation of prosthetic heart valves. The aim of the invention is to reduce the risk to the patient during the implantation. To achieve this, according to the invention a prosthetic heart valve with anchorage supports is temporarily housed in a folded form in a cartridge-type unit ( 4 ) during the implantation. The cartridge-type unit can be fixed on the proximal end of a guide system ( 1 ), which includes a flexible region ( 9 ) that can be guided through the aorta. Actuating elements ( 2, 3 ) run through the interior of the hollow guide system, said elements permitting sections of the cartridge-type unit to be displaced radially about their longitudinal axis and/or laterally in a proximal direction, thus allowing individual sections of the anchorage support and the associated prosthetic heart valve to be sequentially released.

First claim

What is claimed is:

1 . A catheter system for implanting a prosthetic heart valve in a patient, the catheter system comprising:
a guide system; a cartridge unit disposed at a distal end of the guide system and configured to retain the prosthetic heart valve in a collapsed state, the cartridge unit comprising a first sleeve and a second sleeve configured to move with respect to the first sleeve; and a handle positioned at a proximal end of the guide system, the handle configured to (i) cause the cartridge unit to turn radially, and (ii) manipulate the cartridge unit to cause sequential movement of the first sleeve and the second sleeve to sequentially transition the prosthetic heart valve from the collapsed state to a partially expanded state and from the partially expanded state to a fully expanded state.

2 . The catheter system of claim 1 , wherein the cartridge unit further comprises a third sleeve, wherein the first sleeve is configured to be disposed within and move with respect to the third sleeve.

3 . The catheter system of claim 1 , wherein the first sleeve comprises at least one anchor configured to engage the prosthetic heart valve.

4 . The catheter system of claim 1 , wherein the handle is configured to cause both axial displacement of the second sleeve and the first sleeve and radial turning movement of the cartridge unit.

5 . The catheter system of claim 1 , wherein sequentially transitioning the prosthetic heart valve from the collapsed state to the partially expanded state releases anchoring supports of the prosthetic heart valve.

6 . The catheter system of claim 5 , wherein the handle is configured to cause the cartridge unit to turn radially to align the anchoring supports with pockets of a heart valve of the patient.

7 . The catheter system of claim 1 , wherein the handle comprises least one manipulator in mechanical communication with the cartridge unit.

8 . The catheter system of claim 1 , wherein the at least one manipulator is configured to threadedly engage the handle.

9 . The catheter system of claim 1 , wherein the handle further comprises a first manipulator configured to cause the guide system to bend.

10 . The catheter system of claim 9 , wherein the handle further comprises a second manipulator configured to cause sequential movement of the first sleeve and the second sleeve.

11 . A method for implanting a prosthetic heart valve, the method comprising:
delivering the prosthetic heart valve to an implantation site of a patient using a catheter system, the catheter system comprising a guide system, a handle positioned at a proximal end of the guide system, and a cartridge unit disposed at a distal end of the guide system and adapted to retain the prosthetic heart valve in a collapsed state, the cartridge unit comprising a first sleeve and a second sleeve adapted to move with respect to the first sleeve; and manipulating the handle to cause the cartridge unit to turn radially; and manipulating the handle to cause sequential movement of the first sleeve and second sleeve to sequentially transition the prosthetic heart valve from (i) the collapsed state to a partially expanded state and (ii) from the partially expanded state to a fully expanded state.

12 . The method of claim 11 , wherein the cartridge unit further comprises a third sleeve and wherein the first sleeve is disposed within the third sleeve.

13 . The method of claim 12 , wherein the first sleeve comprises at least one anchor adapted to engage the prosthetic heart valve, the method further comprising manipulating the handle to cause the first sleeve to move with respect to the third sleeve to disengage the prosthetic heart valve from the anchor.

14 . The method of claim 11 , wherein manipulating the handle to cause the cartridge unit to turn radially comprises rotating at least a portion of the handle.

15 . The method of claim 11 , wherein sequentially transitioning the prosthetic heart valve from the collapsed state to the partially expanded state releases anchoring supports of the prosthetic heart valve.

16 . The method of claim 15 , wherein manipulating the handle to cause the cartridge unit to turn radially comprises causing the cartridge unit to turn radially to align the anchoring supports with pockets of a heart valve of the patient.

17 . The method of claim 11 , wherein the handle comprises least one manipulator in mechanical communication with the cartridge unit.

18 . The method of claim 11 , wherein the handle comprises a manipulator adapted to cause the guide system to bend.

19 . The method of claim 18 , further comprising manipulating the manipulator to cause the guide system to bend to cause the cartridge unit to traverse an aorta of the patient.

20 . The method of claim 18 , wherein the handle further comprises a second manipulator adapted to cause sequential movement of the first sleeve and the second sleeve.

Assignees

• Jenavalve Tech Inc

Inventors

• Ottma Rudiger
• Moszner Robert
• Figulla Hans-Reiner
• Ferrari Markus
• Damm Christoph

Classifications

• A61F2/2436

  Deployment by retracting a sheath · CPC title

• A61F2/9517

  handle assemblies therefor · CPC title

• A61F2240/008

  Means for testing implantable prostheses · CPC title

• A61F2/2418 Primary

  Scaffolds therefor, e.g. support stents · CPC title

• A61M25/0108

  using radio-opaque or ultrasound markers · CPC title