Antihypertensive peptide probiotic goat milk powder and preparation method thereof

US12564618B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-12564618-B2
Application numberUS-202519208663-A
CountryUS
Kind codeB2
Filing dateMay 15, 2025
Priority dateJun 7, 2024
Publication dateMar 3, 2026
Grant dateMar 3, 2026

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

An antihypertensive peptide probiotic goat milk powder and a preparation method thereof are provided. Goat milk is used as a raw material, the goat milk is sterilized and then cooled, and the screened probiotic bacteria for fermenting goat milk to produce antihypertensive peptides, namely Lacticaseibacillus rhamnosus KD5 (which is preserved in CCTCC on Sep. 7, 2023, with a preservation number of CCTCC NO: M20231641), is added and stirred evenly, and then fermented at a constant temperature. After the fermentation is completed, probiotic fermented goat milk containing antihypertensive peptides is obtained. After mixing the probiotic fermented goat milk evenly with or without nutritional fortifiers for middle-aged and elderly people, it is subjected to vacuum low-temperature spray-drying to obtain antihypertensive peptide probiotic goat milk powder, which has a high ACE inhibition rate and can be used to assist consumers in lowering blood pressure.

First claim

Opening claim text (preview).

What is claimed is: 1 . A method of making an antihypertensive probiotic dairy product, comprising: (1) inoculating 0.01% to 0.05% of lyophilized powder of Lacticaseibacillus rhamnosus KD5 into sterilized and cooled goat milk to obtain a mixture; and (2) fermenting the mixture at a constant temperature of 34° C. to 40° C. for 22 to 26 hours, wherein the Lacticaseibacillus rhamnosus KD5 is preserved at China Center for Type Culture Collection (CCTCC) with a preservation number of CCTCC NO: M20231641, and the antihypertensive probiotic dairy product comprises 16 peptides of amino acid sequences SEQ ID NO: 1-16.

Assignees

Inventors

Classifications

  • Lactobacilli, e.g. L. acidophilus or L. brevis · CPC title

  • Milk; Whey; Colostrum · CPC title

  • characterised by using a Lactobacillus sp. other than Lactobacillus Bulgaricus, including Bificlobacterium sp. · CPC title

  • A23C9/1232Primary

    in powdered, granulated or dried solid form · CPC title

  • Rhamnosus · CPC title

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What does patent US12564618B2 cover?
An antihypertensive peptide probiotic goat milk powder and a preparation method thereof are provided. Goat milk is used as a raw material, the goat milk is sterilized and then cooled, and the screened probiotic bacteria for fermenting goat milk to produce antihypertensive peptides, namely Lacticaseibacillus rhamnosus KD5 (which is preserved in CCTCC on Sep. 7, 2023, with a preservation number…
Who is the assignee on this patent?
Univ Shaanxi Science & Tech
What technology area does this patent fall under?
Primary CPC classification A23C9/1232. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Mar 03 2026 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).