Devices and methods for treating a breathing-related sleep disorder, methods of use and control processes for such a device

Patent metadata

Field	Value
Publication number	US-12564539-B2
Application number	US-201817282384-A
Country	US
Kind code	B2
Filing date	Oct 3, 2018
Priority date	Oct 3, 2018
Publication date	Mar 3, 2026
Grant date	Mar 3, 2026

Abstract

The present teachings relate to a device and a method for treating a subject, wherein an actuator is configured for external mechanical contact with the subject, wherein a control unit is configured to control the actuator to provide at least one burst of a primary vibration, and wherein the primary vibration has one or several frequencies, or a frequency varying, within an operative frequency range contained in a range from 5 Hz to 1000 Hz, in order for the device to generate a shear wave which propagates inside the body of the subject. In addition, the present teachings relate to use of a device of the present teachings to treat a breathing-related sleep disorder, including snoring, OSA, UARS, or OHS.

First claim

The invention claimed is:

1 . A device comprising a first actuator, and a control unit,
wherein the first actuator is configured for external mechanical contact with the subject, wherein the control unit is configured to control the first actuator to provide at least one burst of a first primary vibration, wherein the first primary vibration has several frequencies within an operative frequency range contained in a range from 5 Hz to 1000 Hz, in order for the device to generate a shear wave inside the body of the subject, wherein the shear wave is generated and/or propagates at or up to a depth of at least 15 millimeters inside the body of the subject, wherein the first primary vibration has a frequency content spanning a delivered frequency band contained in, or overlapping, the operative frequency range contained in a range from 5 Hz to 1000 Hz, and wherein the first primary vibration is or contains a vibration which, during a given burst, is a summation of at least several distinct periodic sub-vibrations occurring simultaneously, several of which each have a distinct primary frequency, the several single primary frequencies being contained in the operative frequency range and spanning the delivered frequency band, wherein the device comprises subsets of actuators, each subset of actuators comprising several actuators, one subset of actuators including said first actuator, each actuator in each subset of actuators being configured for external mechanical contact with the subject, wherein the control unit is configured to control each actuator in each subset of actuators to provide at least one burst of primary vibrations, which are synchronous within a given subset and exhibit a phase shift between different subsets, and wherein each primary vibration has several frequencies within the operative frequency range contained in a range from 5 Hz to 1000 Hz.

2 . The device of claim 1 , wherein the operative frequency range is contained in a range from 15 Hz to 200 Hz.

3 . The device of claim 1 , wherein the control unit is configured to control the actuators to provide said at least one burst of the first primary vibration, wherein said burst has a burst duration, and to provide a train of several successive bursts of primary vibration, until the expiration of a burst train duration.

4 . The device of claim 1 , wherein the control unit is configured to turn on or off the actuators based on the measurement of at least one physiological parameter of a subject.

5 . The device of claim 1 , wherein the actuators are arranged on a holder in the form of at least one of:
a neck belt, a thoracic belt or vest, a diaphragmatic belt, an abdominal belt.

6 . A method of treating a subject in need thereof, said method comprising
providing at least one burst of at least one first primary vibration to the subject by external contact of at least one actuator with the subject, in order to generate a shear wave in the subject and to induce a physiological change in the subject in response to the shear wave, wherein the shear wave is generated and/or propagates at or up to a depth of at least 15 millimeters inside the body of the subject, wherein the first primary vibration is or contains a vibration which, during a given burst, is a summation of at least several distinct periodic sub-vibrations, several of which each have a distinct primary frequency, the several single primary frequencies being contained in the operative frequency range and spanning the delivered frequency band wherein the device comprises different subsets of actuators, each subset of actuators comprising several actuators, one subset of actuators including said first actuator, each actuator in each subset of actuators being configured for external mechanical contact with the subject, wherein the control unit is configured to control each actuator in each subset of actuators to provide at least one burst of primary vibrations, which are synchronous within a given subset and exhibit a phase shift between different subsets, and wherein each primary vibration has several frequencies within the operative frequency range contained in a range from 5 Hz to 1000 Hz.

7 . The method of claim 6 , wherein the first primary vibration has a frequency content spanning a delivered frequency band contained in, or overlapping, the operative frequency range.

8 . The method of claim 7 ,
wherein the first primary vibration is or contains a sweeping vibration having a varying frequency which, during a given time interval, has a non-constant frequency spanning the delivered frequency band.

9 . The method of claim 7 , wherein the delivered frequency band spans at least from 15 to 800 Hz.

10 . The method of claim 6 , wherein the physiological change remains for a remanence duration after the provision of any primary vibration has been stopped.

Assignees

• Breas Medical Ab
• Institut National De La Sante Et De La Rech Medicale Inserm Epst
• Univ Claude Bernard Lyon 1 Ucbl
• Centre Leon Berard
• Inst Nat Sante Rech Med
• Univ Claude Bernard Lyin 1 Ucbl
• Centre Lyon Berard

Inventors

• Menguy Didier
• Chapelon Jean-Yves
• Catheline Stefan
• Zorgani Ali

Classifications

• A61H2230/425

  used as a control parameter for the apparatus · CPC title

• A61H2230/201

  used as a control parameter for the apparatus · CPC title

• A61H2201/5005

  for controlling frequency distribution, modulation or interference of a driving signal · CPC title

• A61H2201/165

  Wearable interfaces · CPC title

• A61H2201/1619

  Thorax · CPC title