Autoinjector

Patent metadata

Field	Value
Publication number	US-12558484-B2
Application number	US-202418605302-A
Country	US
Kind code	B2
Filing date	Mar 14, 2024
Priority date	Nov 6, 2012
Publication date	Feb 24, 2026
Grant date	Feb 24, 2026

Abstract

An autoinjector includes a case, a door hingedly coupled to the case and having an open position and a closed position, a plunger slidably disposed in the case, and at least one drive spring applying a biasing force on the plunger relative to the case, wherein the door is operably coupled to the plunger, and wherein rotation of the door from the closed position to the open position moves the plunger from a distal position in the case to a proximal position in the case and compresses the at least one drive spring.

First claim

The invention claimed is:

1 . An autoinjector comprising:
a case configured to receive a syringe; a slidable member that is movable axially within the case to cause at least a portion of the syringe to move axially when the syringe is disposed within the case for dispensing a medicament through a needle of the syringe; a locking member configured to prevent actuation of the slidable member when the autoinjector is in a pre-dispense configuration; a sleeve coupled to a distal end of the case and surrounding at least a portion of a needle of the syringe when the syringe is disposed within the case; two drive springs coupled to the slidable member and configured to apply a biasing force that acts on the slidable member to move the slidable member distally within the case, wherein the two drive springs are parallel to each other and are parallel to a distal direction; a door hingedly coupled to the case and adjustable between an open position and a closed position; and a linkage that couples the door to the case, wherein the linkage is further coupled to at least one of the two drive springs.

2 . The autoinjector of claim 1 , wherein the sleeve is configured to allow push-actuation of the autoinjector when the sleeve is pushed against an injection site.

3 . The autoinjector of claim 1 , further comprising an elongate member extending proximally from the sleeve and configured to deflect the locking member to allow actuation of the slidable member.

4 . The autoinjector of claim 3 , wherein the sleeve is slidable relative to the case between:
a retracted position in which the sleeve is contained within the case along a majority of its length, and an extended position in which the sleeve extends distally from the case by a distance greater than which it extends in the retracted position.

5 . The autoinjector of claim 4 , wherein the extended position of the sleeve corresponds to the pre-dispense configuration of the autoinjector.

6 . The autoinjector of claim 5 , wherein a distal end of the locking member has a first ramped surface, wherein a proximal end of the elongate member has a second ramped surface, and wherein the first and second ramped surfaces abut each other when the autoinjector is in the pre-dispense configuration.

7 . The autoinjector of claim 3 , wherein the elongate member is configured to deflect the locking member when the sleeve is pushed against the injection site.

8 . The autoinjector of claim 7 , wherein deflection of the locking member allows the slidable member to move in the distal direction under the biasing force of the two drive springs.

9 . The autoinjector of claim 3 , wherein a distal end of the locking member has a first ramped surface, wherein a proximal end of the elongate member has a second ramped surface, and wherein the first and second ramped surfaces abut each other when the autoinjector is in the pre-dispense configuration.

10 . The autoinjector of claim 3 , wherein a distal end of the locking member has a first ramped surface, wherein a proximal end of the elongate member has a second ramped surface, and wherein the first and second ramped surfaces abut each other when the autoinjector is in the pre-dispense configuration, wherein the elongate member is configured to deflect the locking member when the sleeve is pushed against the injection site, wherein deflection of the locking member allows the slidable member to move in the distal direction under the biasing force of the two drive springs, and wherein at least one of the two drive springs comprises a tension spring.

11 . The autoinjector of claim 1 , wherein at least one of the two drive springs comprises a tension spring.

12 . The autoinjector of claim 1 , wherein the door is biased to the open position.

13 . The autoinjector of claim 1 , wherein the door is configured to be maintained in the closed position.

14 . The autoinjector of claim 1 , further comprising a collar that is configured to engage a needle boot of the syringe when the syringe is disposed within the case.

15 . The autoinjector of claim 1 , further comprising one or more user feedback mechanisms associated with an injection.

16 . The autoinjector of claim 1 , further comprising a visual feedback mechanism associated with a progress of an injection.

17 . The autoinjector of claim 16 , wherein the visual feedback mechanism is viewable at the door.

18 . The autoinjector of claim 16 , wherein at least a portion of the visual feedback mechanism is disposed on the door.

19 . The autoinjector of claim 1 , further comprising an audible feedback associated with an injection.

20 . A system comprising:
a syringe containing a medicament; and an autoinjector comprising:
a case configured to receive the syringe;
a slidable member that is movable axially within the case to cause at least a portion of the syringe to move axially when the syringe is disposed within the case for dispensing the medicament through a needle of the syringe;
a locking member configured to prevent actuation of the slidable member when the autoinjector is in a pre-dispense configuration;
a sleeve coupled to a distal end of the case and surrounding at least a portion of a needle of the syringe when the syringe is disposed within the case;
two drive springs coupled to the slidable member and configured to apply a biasing force that acts on the slidable member to move the slidable member distally within the case, wherein the two drive springs are parallel to each other and are parallel to a distal direction;
a door hingedly coupled to the case and adjustable between an open position and a closed position; and
a linkage that couples the door to the case,
wherein the linkage is further coupled to at least one of the two drive springs.

21 . The system of claim 20 , further comprising a data storage device configured to store data related to one or more of the medicament, the autoinjector, a patient, and an indicator.

22 . The system of claim 21 , wherein the system is configured to transmit the data.

23 . The system of claim 20 , wherein the syringe comprises a syringe barrel and a needle shroud that is coupled telescopically to the syringe barrel.

24 . The system of claim 23 , wherein the needle shroud is spring-actuated.

25 . The system of claim 23 , wherein the needle shroud is configured to be locked in an extended position relative to the syringe barrel following a dispense of the medicament from the needle.

26 . The system of claim 23 , wherein the needle shroud is configured to be locked in an extended position relative to the syringe barrel following a dispense of the medicament from the needle, and wherein the sleeve is configured to extend proximally from the case following a dispense of the medicament from the needle.

Assignees

• Sanofi Aventis Deutschland

Inventors

• Henderson Charley
• Cross David
• Jennings Douglas Ivan
• Mcginley Ryan Anthony

Classifications

• A61M5/3245

  Constructional features thereof, e.g. to improve manipulation or functioning · CPC title

• A61M5/3129

  Syringe barrels (A61M5/3205 and A61M5/50 take precedence) · CPC title

• A61M2205/3368

  Temperature · CPC title

• A61M2205/6009

  for matching patient with his treatment, e.g. to improve transfusion security · CPC title

• A61M2205/60

  with identification means · CPC title