Blood purification apparatus

Patent metadata

Field	Value
Publication number	US-12558467-B2
Application number	US-202118014620-A
Country	US
Kind code	B2
Filing date	Jun 7, 2021
Priority date	Jul 9, 2020
Publication date	Feb 24, 2026
Grant date	Feb 24, 2026

Abstract

A blood circuit and a dialysate circuit bidirectionally circulate a fluid through a blood purification membrane of a blood purifier, and include a first flow route that causes a dialysate to flow from the dialysate circuit into the blood circuit through a connection flow route connecting the dialysate circuit to the blood circuit while bypassing the blood purifier, and a second flow route that causes the dialysate to flow from the dialysate circuit into the blood circuit through the blood purification membrane. The controller performs control such that blood in the blood circuit is returned to the body by feeding the dialysate to one of these flow routes, determine if a flow amount of the dialysate reaches a predetermined flow amount, and control such that the blood in the blood circuit is returned to the body by feeding the dialysate to the other one of these flow routes.

First claim

The invention claimed is:

1 . A blood purification apparatus comprising:
a blood circuit and a dialysate circuit configured to bidirectionally circulate a fluid through a blood purification membrane of a blood purifier; and a controller, wherein the blood circuit and the dialysate circuit include:
a first flow route that causes a dialysate to flow from the dialysate circuit into the blood circuit through a connection flow route that connects the dialysate circuit to the blood circuit while bypassing the blood purifier, and
a second flow route that causes the dialysate to flow from the dialysate circuit into the blood circuit through the blood purification membrane,
wherein the blood circuit comprises a first pump; wherein the dialysate circuit is attached to an air introducer that comprises a second pump and a first valve, wherein the connection flow route comprises a second valve; wherein the controller is configured to:
perform control such that the first valve closes, the second valve opens, the first pump performs a first rotation, the second pump stops a second rotation, and blood in the blood circuit is returned to a body by feeding the dialysate to one of the first flow route and the second flow route,
determine whether or not a flow amount of the dialysate reaches a predetermined flow amount, and
perform control such that the first valve opens, the second valve closes, the first pump stops the first rotation, the second pump performs the second rotation, and the blood in the blood circuit is returned to the body by feeding the dialysate to an other one of the first flow route and the second flow route in response to determination that the flow amount of the dialysate reaches the predetermined flow amount.

2 . The blood purification apparatus according to claim 1 , further comprising:
a dialysate supplier that supplies the dialysate to the dialysate circuit; and
a dialysate filter that stores the dialysate supplied from the dialysate supplier,
wherein the controller performs control such that the dialysate returns the blood in the blood circuit to the body by feeding the dialysate stored in the dialysate filter to the one of the first flow route and the second flow route in a state where the dialysate supplier does not supply the dialysate to the dialysate circuit.

3 . The blood purification apparatus according to claim 1 , wherein
the first flow route further includes a flow route that causes the dialysate to flow from the dialysate circuit into a blood removal side circuit and a blood return side circuit through the connection flow route, and the second flow route further includes a flow route that causes the dialysate to flow from the dialysate circuit into the blood return side circuit.

4 . The blood purification apparatus according to claim 1 , wherein
the first flow route further includes a flow route that causes the dialysate to flow from the dialysate circuit into a blood return side circuit and a blood removal side circuit through the connection flow route, and the second flow route further includes a flow route that causes the dialysate to flow from the dialysate circuit into the blood removal side circuit.

5 . The blood purification apparatus according to claim 1 , wherein
the first flow route further includes a flow route that causes the dialysate to flow from the dialysate circuit into a blood removal side circuit and a blood return side circuit through the connection flow route, the blood circuit and the dialysate circuit further include a third flow route that causes the dialysate to flow from the dialysate circuit into the blood return side circuit and the blood removal side circuit through the connection flow route while bypassing the blood purifier, the controller performs control such that the blood in the blood circuit is returned to the body by feeding the dialysate to one of the first flow route and the third flow route, the controller determines whether or not the flow amount of the dialysate reaches a predetermined second flow amount, and the controller performs control such that the blood in the blood circuit is returned to the body by feeding the dialysate to the other one of the first flow route and the third flow route in response to determination that the flow amount of the dialysate reaches the predetermined second flow amount.

6 . The blood purification apparatus according to claim 1 , wherein
the second flow route further includes a flow route that causes the dialysate to flow from the dialysate circuit into a blood return side circuit, the blood circuit and the dialysate circuit further include a fourth flow route that causes the dialysate to flow from the dialysate circuit into a blood removal side circuit through the blood purification membrane, the controller performs control such that the blood in the blood circuit is returned to the body by feeding the dialysate to one of the second flow route and the fourth flow route, the controller determines whether or not the flow amount of the dialysate reaches a predetermined third flow amount, and the controller performs control such that the blood in the blood circuit is returned to the body by feeding the dialysate to the other one of the second flow route and the fourth flow route in response to determination that the flow amount of the dialysate reaches the predetermined third flow amount.

7 . The blood purification apparatus according to claim 1 , wherein
after a blood purification treatment in a prescribed treatment mode, the controller selects one of the first flow route and the second flow route as a flow route for the dialysate based on the treatment mode in order to return the blood in the blood circuit to the body.

8 . The blood purification apparatus according to claim 7 , wherein
in a case where the treatment mode indicates any of a hemofiltration treatment and a hemodiafiltration treatment,
the controller performs control such that the blood in the blood circuit is returned to the body by selecting the second flow route as the flow route for the dialysate and feeding the dialysate to the second flow route, and
the controller performs control such that the blood in the blood circuit is returned to the body by feeding the dialysate to the first flow route in response to the determination that the flow amount of the dialysate reaches the predetermined flow amount.

9 . A blood purification apparatus comprising:
a blood circuit and a dialysate circuit configured to bidirectionally circulate a fluid through a blood purification membrane of a blood purifier; and a controller, wherein the blood circuit and the dialysate circuit include:
a first flow route that causes a dialysate to flow from the dialysate circuit into the blood circuit through a connection flow route that connects the dialysate circuit to the blood circuit while bypassing the blood purifier, and
a second flow route that causes the dialysate to flow from the dialysate circuit into the blood circuit through the blood purification membrane,
wherein the blood circuit comprises a first pump, wherein the dialysate circuit is attached to an air introducer that comprises a second pump and a first valve, wherein the connection flow route comprises a second valve, wherein the controller is configured to:
perform control such that the first valve closes, the second valve opens, the first pump performs a first rotation, the second pump stops a second rotation, and blood in the blood circuit is returned to a body by feeding the dialysate to one of the first flow route and the second flow route,
determine whether or not a return flow amount of the blood reaches a predetermined blood return amount, and
perform

Assignees

• Nikkiso Co Ltd

Inventors

• Chiaki Hikaru
• Menjoh Yuya
• Tsuji Kazuya
• Akita Kunihiko

Classifications

• A61M1/165

  with a dialyser bypass on the dialysis fluid line · CPC title

• A61M1/1605 Primary

  Physical characteristics of the dialysate fluid · CPC title

• A61M1/3652

  using gas, e.g. air · CPC title

• A61M1/365

  through membranes, e.g. by inverted trans-membrane pressure [TMP] · CPC title

• A61M1/3649

  using dialysate as priming or rinsing liquid · CPC title