Compacted Hemostatic Cellulosic Aggregates
US-2024173457-A1 · May 30, 2024 · US
Coating-securing agent
US12558452B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12558452-B2 |
| Application number | US-202017439938-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 13, 2020 |
| Priority date | Mar 20, 2019 |
| Publication date | Feb 24, 2026 |
| Grant date | Feb 24, 2026 |
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- Title
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Abstract
Official abstract text for this publication.
Provided is a coating-fixing agent for transplanting a cell or a tissue onto the surface of an organ, intestinal membrane, peritoneal membrane, etc. Provided are: a formulation for coating and fixing a graft, the formulation comprising alginate; a formulation kit for coating and fixing a graft, comprising a formulation containing alginate and a divalent or higher valent metal salt in combination; and a method for transplanting a graft, comprising: transplanting the graft to a transplant site of a human or a non-human animal, and coating the graft with alginate.
First claim
Opening claim text (preview).
The invention claimed is: 1 . A method for transplanting a graft onto an organ surface, comprising: (a) detaching a membrane or layer covering the organ surface at a transplant site of a human or a non-human animal, (b) transplanting the graft to the transplant site on the organ surface of (a), wherein the graft contacts directly with the organ surface, and (c) coating the graft of (b) with a gel formed with alginate and a divalent or higher valent metal ion, thereby fixing the graft onto the transplant site after the graft has been transplanted onto the organ surface. 2 . The method for transplanting a graft according to claim 1 , wherein the alginate is at least one selected from the group consisting of sodium alginate, potassium alginate and ammonium alginate. 3 . The method according to claim 1 , wherein the graft is a cell, a cell condensate, a tissue or a combination thereof. 4 . The method according to claim 1 , wherein the divalent or higher valent metal ion is a calcium ion. 5 . A method for transplanting a graft onto an organ surface, comprising: after transplanting the graft to a transplant site on an organ surface of a human or a non-human animal, adding dropwise to the graft an aqueous solution containing at least one selected from the group consisting of sodium alginate, potassium alginate and ammonium alginate, and further adding dropwise a divalent or higher valent metal ion to gelate the alginate for coating the graft, wherein the graft contacts directly the organ surface.
Assignees
Inventors
Classifications
Alginic acid; Derivatives thereof · CPC title
Growth factors · CPC title
Flowable or injectable implant compositions · CPC title
- A61L24/08Primary
Polysaccharides {(A61L24/043 takes precedence)} · CPC title
Macromolecular materials · CPC title
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- What does patent US12558452B2 cover?
- Provided is a coating-fixing agent for transplanting a cell or a tissue onto the surface of an organ, intestinal membrane, peritoneal membrane, etc. Provided are: a formulation for coating and fixing a graft, the formulation comprising alginate; a formulation kit for coating and fixing a graft, comprising a formulation containing alginate and a divalent or higher valent metal salt in combinatio…
- Who is the assignee on this patent?
- Public Univ Corp Yokohama City Univ
- What technology area does this patent fall under?
- Primary CPC classification A61L24/08. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Feb 24 2026 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).