Slide-scanner control

Patent metadata

Field	Value
Publication number	US-12554110-B2
Application number	US-202017631385-A
Country	US
Kind code	B2
Filing date	Aug 5, 2020
Priority date	Aug 6, 2019
Publication date	Feb 17, 2026
Grant date	Feb 17, 2026

Abstract

Control processes for a slide-scanning system comprising a carousel with a plurality of rack slots configured to receive slide racks via an exposed portion of the scanning system. In an embodiment, initializing the scanning system comprises automatically homing back-end and front-end components, wherein the front-end components comprise the carousel. An inventory of all slide racks in the carousel is automatically generated. If any slide rack was being processed by any back-end components, the slide rack is automatically unloaded into a corresponding rack slot. In addition, the carousel is automatically positioned to expose a starting subset of the rack slots within the exposed portion. This starting subset may comprise a maximum segment of adjacent empty rack slots.

First claim

What is claimed is:

1 . A scanning system comprising:
a plurality of front-end components comprising a carousel and a first set of motors and sensors, the carousel comprising a plurality of rack slots configured to receive a plurality of slide racks, wherein a first portion of the carousel is an exposed portion in which a portion of the carousel is accessible from an external environment of the scanning system and a second portion of the carousel is inaccessible from the external environment, wherein each rack slot is associated, or is associable, with a detector that is positioned to determine whether or not the rack slot is occupied by a slide rack; a plurality of back-end components for processing the slide rack, the plurality of back-end components comprising a second set of motors and sensors to load and unload slide racks from the carousel and move glass slides between an unloaded slide rack and a scanning stage; and at least one hardware processor configured to:
control the plurality of back-end components according to a back-end state machine and control the plurality of front-end components according to a front-end state machine that operates independently from the back-end state machine,
wherein the front-end state machine is configured to control the first set of motors and sensors and the back-end state machine is configured to control the second set of motors and sensors,
cause movement of each of the front-end components and the back-end components to respective initial zero positions by controlling the respective front-end state machine and back-end state machine,
generate an inventory of all of the slide racks within the plurality of rack slots of the carousel,
determine if any one of the slide racks is unloaded from the carousel to the back-end components based on the inventory,
in response to the one of the slide racks being unloaded from the carousel, return the one of the slide racks to a corresponding one of the rack slots of the carousel by controlling the respective front-end state machine and back-end state machine, and
position the carousel to expose a starting subset of the plurality of rack slots within the first portion of the carousel by controlling the respective front-end state machine and back-end state machine.

2 . The scanning system of claim 1 , wherein the at least one hardware processor is further configured to:
identify a largest contiguous segment of empty rack slots from the plurality of rack slots, and select the largest contiguous segment of empty rack slots as part of the starting subset of the plurality of rack slots.

3 . The scanning system of claim 2 , wherein each of the plurality of rack slots is associated with an index representing its order among the plurality of rack slots, wherein the at least one hardware processor is further configured to:
when there are two or more largest contiguous segments of adjacent empty rack slots, select one of the two or more largest contiguous segments, as the starting subset, based on the indexes associated with the rack slots within the two or more largest contiguous segments.

4 . The scanning system of claim 1 , further comprising:
a limit switch; and an encoder configured to govern the positioning of the carousel, wherein causing movement of each of the front-end components and the back-end components to respective initial zero positions comprises:
triggering a limit switch by rotating the carousel in a first direction;
backing off the limit switch by rotating the carousel in a second direction, opposite the first direction;
triggering the limit switch by rotating the carousel in the first direction; and
zeroing the encoder.

5 . The scanning system of claim 1 , further comprising:
a scanning stage configured to scan a slide when loaded onto the scanning stage, wherein the at least one hardware processor is further configured to:
control a push-pull assembly to unload the slide from the scanning stage into a corresponding slide slot in the one of the slide racks, prior to returning the one of the slide racks to the corresponding one of the rack slots.

6 . The scanning system of claim 1 , wherein the at least one hardware processor is further configured to:
implement a touch sensor to receive a user selection of a slide rack corresponding to one of the plurality of rack slots, if the selected slide rack is being processed by the scanning system, interrupt processing of the selected slide rack, and control an assembly to return the selected slide rack into a corresponding one of the rack slots, and position the carousel such that the corresponding one of the rack slots is positioned within the first portion of the carousel accessible from the external environment.

7 . The scanning system of claim 1 , further comprising:
a plurality of visual indicators that are each associated with one of the plurality of rack slots positioned within the first portion of the carousel accessible from the external environment, each of the plurality of visual indicators associated with a respective light emitting diode, wherein the at least one hardware processor is further configured to, for each of the plurality of rack slots positioned within the first portion of the carousel accessible from the external environment:
detect a status of the rack slot; and
control the light emitting diode to implement the visual indicator associated with the rack slot to indicate the detected status.

8 . The scanning system of claim 1 , wherein the at least one hardware processor is further configured to:
implement a sensor to detect insertion of a slide rack into one of the plurality of rack slots in the first portion of the carousel accessible from the external environment, and in response to detecting insertion of the slide rack into the one of the rack slots, update a status of the one of the rack slots to reflect that the one of the rack slots is occupied by the slide rack.

9 . The scanning system of claim 1 , further comprising:
a light curtain formed around the first portion of the carousel accessible from the external environment to detect presence of an object, wherein the at least one hardware processor is further configured to prevent the rotation of the carousel based on identifying the object by:
implementing one or more transmitter and receiver pairs to form the light curtain;
detecting interruption of the light curtain, and
preventing rotation of the carousel while the interruption of the light curtain is detected.

10 . The scanning system of claim 9 , wherein the at least one hardware processor is further configured to:
determine to rotate the carousel, in response to determining to rotate the carousel, delay rotation of the carousel for a delay period, and in response to an input received via a touch sensor, reset the delay period whenever an interruption of the light curtain is detected.

11 . The scanning system of claim 10 , further comprising:
a display, wherein the at least one hardware processor is further configured to:
control the display to indicate a remaining amount of the delay period.

12 . The scanning system of claim 1 , wherein the at least one hardware processor is further configured to counter potential drift relative to a position of an encoder reported by a drive motor of the carousel by:
implementing a counter to monitor a rotational distance traveled by the carousel, and in response to determining that the rotational distance exceeds a predetermined threshold, performing drift correction for the carousel by breaking from any active rotational operation, and perform a homing process on the carousel t

Assignees

• Leica Biosystems Imaging Inc

Inventors

• Najmabadi Peyman
• Newberg Nicholas
• Djelosevic Prentash
• Stearrett Aaron

Classifications

• G02B21/34

  Microscope slides, e.g. mounting specimens on microscope slides · CPC title

• G02B21/086

  for transillumination only · CPC title

• G01V8/20

  using multiple transmitters or receivers · CPC title

• G01N2035/00138

  Slides · CPC title

• G01N2035/00049

  for loading/unloading a carousel · CPC title