N-heptyl-glyceryl ether and synergistically active preservatives

Patent metadata

Field	Value
Publication number	US-12551421-B2
Application number	US-202118257865-A
Country	US
Kind code	B2
Filing date	Dec 13, 2021
Priority date	Dec 17, 2020
Publication date	Feb 17, 2026
Grant date	Feb 17, 2026

Abstract

A composition contains n-heptyl-glyceryl ether and at least one further carefully chosen and synergistically active preservative.

First claim

The invention claimed is:

1 . A composition, comprising:
A) n-heptyl-glyceryl ether, and B) at least one selected from the group consisting of p-anisic acid, benzoic acid, sorbic acid, lactic acid, and salts of any of the before mentioned acids, and phenylpropanol, and wherein the composition has a pH in the range of 4.0 to 8.5.

2 . The composition according to claim 1 , wherein component A) and component B) are comprised in a weight ratio of from 99:1 to 1:99.

3 . The composition according to claim 1 , wherein component A) is comprised in an amount of from of from 0.005 wt.-% to 99.0 wt.-%, wherein the weight percentages refer to a total composition.

4 . The composition according to claim 1 , wherein component B) is comprised in an amount of from 0.005 wt.-% to 99.0 wt.-%, wherein the weight percentages refer to a total composition.

5 . The composition according to claim 1 , wherein the composition comprises
C) at least one selected from the group consisting of deodorant and antiperspirant active ingredients.

6 . The composition according to claim 1 , wherein the composition comprises
D) at least one antioxidant.

7 . A formulation, comprising the composition according to claim 1 , wherein the formulation is selected from the group consisting of cleaning formulations, defoamers, coating formulations, and cosmetic formulations.

8 . The formulation according to claim 7 , wherein
component A) is comprised in an amount of from of from 0.005 wt.-% to 10.0 wt.-%, and component B) is comprised in an amount of from 0.005 wt.-% to 30.0 wt.-%, and optionally, component C), which is at least one selected from the group consisting of deodorant and antiperspirant active ingredients, is comprised in an amount of from 0.005 wt.-% to 25.0 wt.-%, wherein the weight percentages refer to a total formulation.

9 . A method for preserving a formulation, the method comprising:
adding the following components to the formulation A) n-heptyl-glyceryl ether, and B) at least one selected from the group consisting of p-anisic acid, benzoic acid, sorbic acid, lactic acid and salts of any of the before mentioned acids, and phenylpropanol.

10 . The method according to claim 9 , wherein the preserving comprises growth reduction of a micro-organism.

11 . A preservative, comprising the composition according to claim 1 .

12 . A method for increasing critical micelle concentration of n-heptyl-glyceryl ether in water, the method comprising:
adding to the water and the n-heptyl-glyceryl ether, at least one selected from the group consisting of B) p-anisic acid and salts thereof.

13 . The composition according to claim 6 , wherein the at least one antioxidant is tocopherol or naringenin.

14 . The method according to claim 9 , wherein the formulation is selected from the group consisting of cleaning formulations, defoamers, coating formulations, and cosmetic formulations.

15 . The method according to claim 10 , wherein the micro-organism is selected from the group consisting of yeast, mould, and bacteria.

16 . The method according to claim 10 , wherein the micro-organism is A. brasiliensis, S. aureus , or C. albicans.

17 . The preservative according to claim 11 , wherein the preservative is a preservative against a micro-organism selected from the group consisting of yeast, mould, and bacteria.

18 . The preservative according to claim 17 , wherein the preservative is a preservative against bacteria comprising A. brasiliensis, S. aureus , or C. albicans.

19 . The composition according to claim 1 , which has synergistic efficiency in antimicrobial activity.

20 . The composition according to claim 19 , wherein the antimicrobial activity is against is A. brasiliensis, S. aureus , or C. albicans.

Assignees

• Evonik Operations Gmbh

Inventors

• Brandt Kathrin Daniela
• Jänichen Jan
• Kinder Michael
• Thiemann Alexander
• Schmitt Ellen
• Scholze Jessica
• Steinmetzer Sabine

Classifications

• A61Q15/00

  Anti-perspirants or body deodorants (deodorisation of air A61L9/00) · CPC title

• A61K2800/524

  Preservatives · CPC title

• A61K8/678

  Tocopherol, i.e. vitamin E · CPC title

• A61K8/498

  having 6-membered rings or their condensed derivatives, e.g. coumarin · CPC title

• A61K8/368

  with carboxyl groups directly bound to carbon atoms of aromatic rings · CPC title