Intraocular implants and methods and kits therefor

Patent metadata

Field	Value
Publication number	US-12551376-B2
Application number	US-202217866429-A
Country	US
Kind code	B2
Filing date	Jul 15, 2022
Priority date	Jun 26, 2006
Publication date	Feb 17, 2026
Grant date	Feb 17, 2026

Abstract

Devices, methods and kits are described for reducing intraocular pressure. The devices include a support that is implantable within Schlemm's canal and maintains the patency of the canal without substantially interfering with transmural fluid flow across the canal. The devices utilize the natural drainage process of the eye and can be implanted with minimal trauma to the eye. Kits include a support and an introducer for implanting the support within Schlemm's canal. Methods include implanting a support within Schlemm's canal, wherein the support is capable of maintaining the patency of the canal without substantial interference with transmural fluid flow across the canal.

First claim

The invention claimed is:

1 . A kit for reducing intraocular pressure, comprising:
a support configured to be implanted circumferentially within Schlemm's canal to maintain patency of at least a portion of Schlemm's canal; an introducer configured to position the support within Schlemm's canal; and a dilating device configured to inject fluid into Schlemm's canal.

2 . The kit of claim 1 , wherein the support is configured to allow transmural fluid flow across Schlemm's canal.

3 . The kit of claim 1 , wherein the support comprises an arcuate member.

4 . The kit of claim 3 , wherein the arcuate member comprises a radius of curvature of about 3 mm to about 8 mm.

5 . The kit of claim 3 , wherein the arcuate member comprises a radius of curvature that is smaller than a radius of curvature of Schlemm's canal.

6 . The kit of claim 1 , wherein the support is configured to extend about one quarter of the way around Schlemm's canal.

7 . The kit of claim 1 , wherein the support is configured to extend about one half of the way around Schlemm's canal.

8 . The kit of claim 1 , wherein the support comprises at least one fenestration.

9 . The kit of claim 8 , wherein the support comprises a plurality of fenestrations.

10 . The kit of claim 1 , wherein the support is non-tubular.

11 . The kit of claim 1 , wherein the support comprises a shape memory material.

12 . The kit of claim 1 , wherein the support is a first support, the kit further comprising at least one second support.

13 . The kit of claim 12 , wherein the first support and the at least one second support are configured to be implanted within different eyes of a patient.

14 . The kit of claim 1 , wherein the introducer comprises a cannula configured to guide the support to Schlemm's canal.

15 . The kit of claim 14 , wherein the cannula is tubular.

16 . The kit of claim 14 , wherein the introducer further comprises a rod configured to advance the support into Schlemm's canal.

17 . The kit of claim 16 , wherein the rod is positioned within a lumen of the cannula.

18 . The kit of claim 17 , wherein the support is positioned at distal end of the rod within the lumen of the cannula.

19 . The kit of claim 1 , wherein the fluid comprises a high viscosity fluid.

20 . The kit of claim 19 , wherein the fluid comprises sodium hyaluronate.

Assignees

• Sight Sciences Inc

Inventors

• Badawi David Y
• Badawi Paul

Classifications

• A61F9/0017

  implantable in, or in contact with, the eye, e.g. ocular inserts · CPC title

• A61F2250/0067

  Means for introducing or releasing pharmaceutical products into the body · CPC title

• A61F2210/0014

  using shape memory or superelastic materials, e.g. nitinol · CPC title

• A61F2210/0004

  bioabsorbable · CPC title

• A61F9/00781 Primary

  Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment (drainage implants in general A61M27/002) · CPC title