System, computer program product and method for ion-based radiotherapy treatment planning

Patent metadata

Field	Value
Publication number	US-12544591-B2
Application number	US-201917053876-A
Country	US
Kind code	B2
Filing date	May 14, 2019
Priority date	May 21, 2018
Publication date	Feb 10, 2026
Grant date	Feb 10, 2026

Abstract

Accumulated path length for ions that reach a particular area of a patient is used in dose planning as an indicator of plan robustness. Also, the magnitude of the variations of the accumulated path lengths is determined for a number of beam directions, allowing beam directions to be selected for maximum robustness in treatment planning.

First claim

The invention claimed is:

1 . A computer-based method for treatment planning of a radiotherapy treatment plan for ion based radiotherapy, performed in a processor, for a selected beam direction, comprising:
obtaining, by the processor, information for each of at least a first and a second portion in a treatment volume, related to accumulated path length of tissue traversed by ions when they reach the portion; calculating, by the processor, an accumulated path length for each of the at least first and second portion; selecting, by the processor for use in a radiotherapy treatment plan for ion based radiotherapy, a beam direction based on each of the calculated accumulated path lengths for the first and second portion in a treatment portion; and communicating, by the processor, the selected beam direction to a radiation therapy system for performing the ion based radiotherapy, the ion based radiotherapy to be performed by the radiation therapy system using the at least one radiotherapy treatment plan.

2 . The method according to claim 1 , wherein the accumulated path length is a Water Equivalent Path Length, WEPL.

3 . The method according to claim 1 , wherein the accumulated path length is a geometrical path length.

4 . The method according to claim 1 , wherein the information related to the accumulated path length of tissue traversed by ions when they reach the portion includes a value indicating an average of the accumulated path lengths traversed by at least two ions that will reach the portion of the treatment volume.

5 . The method according to claim 1 , further comprising:
calculating the accumulated path lengths for each of at least two beam directions; determining each of the at least two possible beam directions including a first beam direction a second beam direction based on the calculated accumulated path lengths for each of the at least two beam directions; and selecting at least one of the first beam direction and the second beam direction to be used in the treatment among the possible beam directions in dependence of their calculated accumulated path lengths.

6 . The method of ion-based radiotherapy treatment planning according to claim 5 , wherein the selection is made as part of a computer-implemented optimization.

7 . A computer program product comprising non-transitory computer readable code means which, when executed in a computer, will cause the computer to perform the method according to claim 1 .

8 . A computer system comprising a processor, a data memory, and a program memory, wherein the program memory comprises a computer program product according to claim 7 .

9 . A non-transitory computer readable medium encoded with computer executable instructions which, when run in a first computer device will cause the device to perform the method according to claim 1 .

10 . A computer-based method for treatment planning of a radiotherapy treatment plan for ion based radiotherapy, performed in a processor, for a selected beam direction, comprising:
obtaining, by the processor, information for each of at least a first and a second portion in a treatment volume, related to accumulated path length of tissue traversed by ions when they reach the portion; calculating, by the processor, an accumulated path length for each of the at least first and second portion of at least two beam directions, the at least two possible beam directions including a first beam direction a second beam direction; selecting, for use in a radiotherapy treatment plan for ion based radiotherapy, at least one of the first beam direction and the second beam direction to be used in the treatment among the possible beam directions in dependence of their calculated accumulated path lengths for the first and second portion in a treatment portion, wherein the selection of the at least one beam direction is performed by an operator; displaying, by the processor in an image of the treatment volume, for each of the first and the second portion of the treatment volume, information representing the calculated accumulated path length; and communicating, by the processor, the selected beam direction to a radiation therapy system for performing the ion based radiotherapy, the ion based radiotherapy to be performed by the radiation therapy system using the at least one radiotherapy treatment plan.

11 . The method according to claim 10 , wherein each calculated accumulated path length is assigned a colour and the step of displaying information representing the calculated accumulated path length that includes displaying a representation of the treatment volume, where each of the at least first and second portions of the treatment volume is displayed in the colour representing the accumulated path length calculated for that portion of the treatment volume.

12 . The method according to claim 10 , wherein each calculated accumulated path length is assigned an elevation level and the step of displaying information representing the calculated accumulated path length that includes displaying a 3-dimensional representation of the treatment volume, where each of the at least first and second portions of the treatment volume is displayed at the elevation level representing the accumulated path length calculated for that portion of the treatment volume.

13 . The method according to claim 10 , wherein the accumulated path length is a Water Equivalent Path Length, WEPL.

14 . The method according to claim 10 , wherein the accumulated path length is a geometrical path length.

15 . The method according to claim 10 , wherein the information related to the accumulated path length of tissue traversed by ions when they reach the portion includes a value indicating an average of the accumulated path lengths traversed by at least two ions that will reach the portion of the treatment volume.

16 . A computer program product comprising non-transitory computer readable code means which, when executed in a computer, will cause the computer to perform the method according to claim 10 .

17 . A computer system comprising a processor, a data memory, and a program memory, wherein the program memory comprises a computer program product according to claim 16 .

18 . A non-transitory computer readable medium encoded with computer executable instructions which, when run in a first computer device will cause the device to perform the method according to claim 10 .

Assignees

• Raysearch Lab Ab

Inventors

• Traneus Erik

Classifications

• A61N2005/1087

  Ions; Protons · CPC title

• A61N2005/1034

  Monte Carlo type methods; particle tracking · CPC title

• G16H20/40

  relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture · CPC title

• A61N5/1031 Primary

  using a specific method of dose optimization · CPC title

• A61N5/103 Primary

  Treatment planning systems · CPC title