Automated segmentation of artifacts in histopathology images
US-2024079116-A1 · Mar 7, 2024 · US
US12541815B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12541815-B2 |
| Application number | US-202218087382-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 22, 2022 |
| Priority date | Dec 24, 2021 |
| Publication date | Feb 3, 2026 |
| Grant date | Feb 3, 2026 |
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A method of outputting a pathology slide image includes receiving a user input related to a method of outputting at least one region included in the pathology slide image, based on the user input, determining an area of a guide to be output on the pathology slide image and a region of the pathology slide image included in the guide, and based on the determined area and region, outputting the pathology slide image on which the guide is overlaid.
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What is claimed is: 1 . A method comprising: receiving, by a processor, a first user input related to a method of outputting at least one region included in a pathology slide image, wherein the first user input related to the method of outputting includes a user input specifying a magnification; based on the first user input, determining, by the processor, an area of a guide to be output on the pathology slide image and a region of the pathology slide image included in the guide; based on the area of the guide and the determined region, outputting, by the processor, the pathology slide image on which the guide is overlaid; determining, by the processor from the pathology slide image, a current region currently being observed by a user as an observed region or non-observed region based on a threshold magnification and the user input specifying the magnification, wherein the observed region comprises at least one previous region which has already been observed by the user in the pathology slide image, updating, by the processor, the observed region by adding, to the at least one previous region, the current region in case that the current region is observed by the user at the magnification being greater than or equal to the threshold magnification; and outputting, by the processor based on the updating, the updated observed region to be distinguished from the non-observed region of the pathology slide image. 2 . The method of claim 1 , wherein the determining of the area of the guide comprises, based on the magnification specified according to the first user input, increasing or decreasing the area of the guide in a state in which the determined region is fixed. 3 . The method of claim 1 , wherein the determining of the area of the guide comprises, based on the magnification specified according to the first user input, enlarging or reducing the determined region in a state in which the area of the guide is fixed. 4 . The method of claim 1 , further comprising, based on an additionally received user input, outputting an enlarged or reduced image of at least a portion of the pathology slide image. 5 . The method of claim 1 , wherein the outputting of the updated observed region comprises outputting a thumbnail image expressed such that the observed region is distinguished from the non-observed region. 6 . The method of claim 1 , further comprising: setting at least one region of interest in the pathology slide image; and determining whether the updated observed region includes the at least one region of interest. 7 . The method of claim 6 , further comprising: receiving a second user input related to termination of observation of the pathology slide image; and based on a result of the determining, generating a notification signal for asking whether to additionally observe the pathology slide image. 8 . A non-transitory computer-readable recording medium having recorded thereon a program for causing a computer to execute the method of claim 1 . 9 . The method of claim 1 , wherein the outputting of the updated observed region comprises: outputting a pathological image display region of the updated observed region with a visual representation, wherein the updated observed region is output on the pathology slide image while being visually distinguished from the non-observed region by the visual representation. 10 . A computing device comprising: at least one memory; and at least one processor, wherein the at least one processor is configured to: determine, based on a first user input related to a method of outputting at least one region included in a pathology slide image, an area of a guide to be output on the pathology slide image and a region of the pathology slide image included in the guide, wherein the first user input related to the method of outputting includes a user input specifying a magnification; control a display device to output the pathology slide image on which the guide is overlaid, based on the area of the guide and the determined region; determine, from the pathology slide image, a current region currently being observed by a user as an observed region or non-observed region based on a threshold magnification and the user input specifying the magnification, wherein the observed region comprises at least one previous region which has already been observed by the user in the pathology slide image, update the observed region by adding, to the at least one previous region, the current region in case that the current region is observed by the user at the magnification being greater than or equal to the threshold magnification; and control the display device to output, based on the updating, the updated observed region to be distinguished from the non-observed region of the pathology slide image. 11 . The computing device of claim 10 , wherein the at least one processor is further configured to, based on the magnification specified according to the first user input, increase or decrease the area of the guide in a state in which the determined region is fixed. 12 . The computing device of claim 10 , wherein the at least one processor is further configured to, based on the magnification specified according to the first user input, enlarge or reduce the determined region in a state in which the area of the guide is fixed. 13 . The computing device of claim 10 , wherein the at least one processor is further configured to, control the display device to output an enlarged or reduced image of at least a portion of the pathology slide image, based on an additionally received user input. 14 . The computing device of claim 10 , wherein the at least one processor is further configured to control the display device to output a thumbnail image expressed such that the updated observed region is distinguished from the non-observed region. 15 . The computing device of claim 10 , wherein the at least one processor is further configured to set at least one region of interest in the pathology slide image, and determine whether the updated observed region includes the at least one region of interest. 16 . The computing device of claim 15 , wherein the at least one processor is further configured to, upon reception of a second user input related to termination of observation of the pathology slide image, generate, based on a result of the determining, a notification signal for asking whether to additionally observe the pathology slide image. 17 . The computing device of claim 10 , wherein the at least one processor is further configured to: control the display device to output a pathological image display region of the updated observed region with a visual representation, and wherein the updated observed region is output on the pathology slide image while being visually distinguished from the non-observed region by the visual representation.
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