Apparatus and method for measuring hormone concentration in biofluids
US-2022170920-A1 · Jun 2, 2022 · US
US12540913B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12540913-B2 |
| Application number | US-202318484919-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 11, 2023 |
| Priority date | Feb 20, 2023 |
| Publication date | Feb 3, 2026 |
| Grant date | Feb 3, 2026 |
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A chemical sensor includes a sensor element; a first electrode electrically connected to the sensor element; a second electrode electrically connected to the sensor element; an aptamer located on a surface of the sensor element; a solution covering the surface of the sensor element and the aptamer; and a tropane derivative having a tropane skeleton and contained in the solution.
Opening claim text (preview).
What is claimed is: 1 . A chemical sensor comprising: a sensor element; a first electrode electrically connected to the sensor element; a second electrode electrically connected to the sensor element; an aptamer located on a surface of the sensor element; a solution covering the surface of the sensor element and the aptamer, the solution contacting a specimen atmosphere; and a tropane derivative having a tropane skeleton and contained in the solution, the chemical sensor detecting methyl benzoate based on a change in electrical characteristic of the sensor element. 2 . The chemical sensor according to claim 1 , wherein the sensor element is graphene. 3 . The chemical sensor according to claim 1 , wherein the aptamer is a cocaine aptamer. 4 . The chemical sensor according to claim 1 , wherein the tropane derivative is tropine, tropinone, or tropane. 5 . A method for detecting a benzoic acid and a benzoic acid derivative, comprising: bringing a specimen into contact with a reagent covering a surface of a sensor element, the reagent containing a solution, an aptamer contained in the solution and located on the surface of the sensor element, and a tropane derivative having a tropane skeleton and contained in the solution; and detecting a benzoic acid or a benzoic acid derivative based on a change in electrical characteristic of the sensor element. 6 . The method according to claim 5 , wherein the sensor element is graphene. 7 . The method according to claim 5 , wherein the aptamer is a cocaine aptamer. 8 . The method according to claim 5 , wherein the tropane derivative is tropine, tropinone, or tropane.
Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction · CPC title
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