System and method for consistency-aware learnable multi-prior reconstruction for magnetic resonance imaging

US12535547B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-12535547-B2
Application numberUS-202418604294-A
CountryUS
Kind codeB2
Filing dateMar 13, 2024
Priority dateApr 25, 2023
Publication dateJan 27, 2026
Grant dateJan 27, 2026

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Abstract

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Techniques for performing iterative MRI image reconstruction by learning complementary multi-prior knowledge from images, k-space data, and calibration data are disclosed. In one method, k-space data is obtained from an MRI scan. Image-space modifications are performed on the k-space data using a first neural network trained to operate on data in image space. The k-space data is converted from the frequency domain to a spatial domain to produce input image-space data. Using the first neural network, output image-space data is generated, which is then converted from the spatial domain to the frequency domain. K-space modifications are performed on the k-space data using a second neural network trained to operate on data in k-space. ACS are encoded using a third neural network to guide the second neural network in learning consistency-aware k-space correlations. The k-space data is converted from the frequency domain to the spatial domain to obtain a reconstructed image.

First claim

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What is claimed is: 1 . A computer-implemented method of performing magnetic resonance imaging (MRI) image reconstruction, the computer-implemented method comprising: obtaining k-space data from an MRI scan, wherein the k-space data is under-sampled in a frequency domain; for each of a set of iterations: performing image-space modifications on the k-space data using a first neural network trained to operate on data in image space by: converting the k-space data from the frequency domain to a spatial domain to produce input image-space data; generating, using the first neural network, output image-space data by inputting the input image-space data into the first neural network; and converting the output image-space data from the spatial domain to the frequency domain to obtain the k-space data incorporating the image-space modifications; and performing k-space modifications on the k-space data using a second neural network trained to operate on data in k-space by inputting the k-space data into the second neural network to obtain the k-space data incorporating the k-space modifications; and converting the k-space data from the frequency domain to the spatial domain to obtain a reconstructed image. 2 . The computer-implemented method of claim 1 , further comprising: zero-filling the k-space data. 3 . The computer-implemented method of claim 1 , further comprising: estimating a set of coil sensitivity maps based on the k-space data, wherein the image-space modifications are performed on the k-space data further using the set of coil sensitivity maps. 4 . The computer-implemented method of claim 3 , wherein the reconstructed image is obtained by using the set of coil sensitivity maps to compensate for an uneven signal reception strength for individual receiver coils used in a multi-coil setup. 5 . The computer-implemented method of claim 1 , further comprising: for each of the set of iterations: performing a frequency fusion operation on the k-space data by summing the k-space data incorporating the image-space modifications and the k-space data incorporating the k-space modifications. 6 . The computer-implemented method of claim 5 , wherein performing the frequency fusion operation includes using an under-sampling pattern to sum the k-space data incorporating the image-space modifications and the k-space data incorporating the k-space modifications. 7 . The computer-implemented method of claim 1 , wherein one or both of the first neural network and the second neural network were previously trained by: obtaining training k-space data; performing the image-space modifications and the k-space modifications on the training k-space data and thereafter converting the training k-space data from the frequency domain to the spatial domain to obtain a training reconstructed image; comparing the training reconstructed image to a reference image to compute a reconstruction loss; and modifying weights associated with one or both of the first neural network and the second neural network based on the reconstruction loss. 8 . The computer-implemented method of claim 1 , wherein the k-space data incorporating the k-space modifications is obtained further using a surface data fidelity layer configured to reduce effects of data imperfections due to padding in the k-space domain. 9 . The computer-implemented method of claim 1 , wherein the k-space data incorporating the k-space modifications is obtained further using a calibration consistency module configured to encode calibration features from auto-calibration signals (ACS) and to guide the second neural network in learning consistency-aware k-space correlations, the calibration consistency module comprising a third neural network. 10 . A non-transitory computer-readable medium comprising instructions that, when executed by one or more processors, cause the one or more processors to perform operations comprising: obtaining k-space data from a magnetic resonance imaging (MRI) scan, wherein the k-space data is under-sampled in a frequency domain; for each of a set of iterations: performing image-space modifications on the k-space data using a first neural network trained to operate on data in image space by: converting the k-space data from the frequency domain to a spatial domain to produce input image-space data; generating, using the first neural network, output image-space data by inputting the input image-space data into the first neural network; and converting the output image-space data from the spatial domain to the frequency domain to obtain the k-space data incorporating the image-space modifications; and performing k-space modifications on the k-space data using a second neural network trained to operate on data in k-space by inputting the k-space data into the second neural network to obtain the k-space data incorporating the k-space modifications; and converting the k-space data from the frequency domain to the spatial domain to obtain a reconstructed image. 11 . The non-transitory computer-readable medium of claim 10 , wherein the operations further comprise: zero-filling the k-space data. 12 . The non-transitory computer-readable medium of claim 10 , wherein the operations further comprise: estimating a set of coil sensitivity maps based on the k-space data, wherein the image-space modifications are performed on the k-space data further using the set of coil sensitivity maps. 13 . The non-transitory computer-readable medium of claim 12 , wherein the reconstructed image is obtained by using the set of coil sensitivity maps to compensate for an uneven signal reception strength for individual receiver coils used in a multi-coil setup. 14 . The non-transitory computer-readable medium of claim 10 , wherein the operations further comprise: for each of the set of iterations: performing a frequency fusion operation on the k-space data by summing the k-space data incorporating the image-space modifications and the k-space data incorporating the k-space modifications. 15 . The non-transitory computer-readable medium of claim 10 , wherein the k-space data incorporating the k-space modifications is obtained further using a calibration consistency module configured to encode calibration features from auto-calibration signals (ACS) and to guide the second neural network in learning consistency-aware k-space correlations, the calibration consistency module comprising a third neural network. 16 . The non-transitory computer-readable medium of claim 10 , wherein the operations further comprise: training one or both of the first neural network and the second neural network by: obtaining training k-space data; performing the image-space modifications and the k-space modifications on the training k-space data and thereafter converting the training k-space data from the frequency domain to the spatial domain to obtain a training reconstructed image; comparing the training reconstructed image to a reference image to compute a reconstruction loss; and modifying weights associated with one or both of the first neural network and the second neural network based on the reconstruction loss. 17 . A system comprising: one or more processors; and a computer-readable medium comprising instructions that, when executed by the one or more processors, cause the one or more processors to perform operations comprising: obtaining k-space data from a magnetic resonance imaging (MRI) scan, wherein the k-space data is under-sampled in a frequency domain; for each of a set of iteration

Assignees

Inventors

Classifications

  • AI-based methods, deep learning or artificial neural networks · CPC title

  • Iterative · CPC title

  • Physics · mapped topic

  • Physics · mapped topic

  • Calibration of imaging systems, e.g. using test probes {, Phantoms; Calibration objects or fiducial markers such as active or passive RF coils surrounding an MR active material} · CPC title

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What does patent US12535547B2 cover?
Techniques for performing iterative MRI image reconstruction by learning complementary multi-prior knowledge from images, k-space data, and calibration data are disclosed. In one method, k-space data is obtained from an MRI scan. Image-space modifications are performed on the k-space data using a first neural network trained to operate on data in image space. The k-space data is converted from …
Who is the assignee on this patent?
Univ Hong Kong Chinese
What technology area does this patent fall under?
Primary CPC classification G01R33/5608. Mapped technology areas include Physics.
When was this patent published?
Publication date Tue Jan 27 2026 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 2 related publications on this page (citations in our corpus or others sharing the same primary CPC).