Microfluidic detection system for refrigerator and refrigerator

Patent metadata

Field	Value
Publication number	US-12535496-B2
Application number	US-202118246540-A
Country	US
Kind code	B2
Filing date	Sep 8, 2021
Priority date	Sep 27, 2020
Publication date	Jan 27, 2026
Grant date	Jan 27, 2026

Abstract

Provided are a microfluidic detection system for a refrigerator and the refrigerator. The microfluidic detection system comprises: a microfluidic biochip that has a sample inlet, a detection pool and a communication port, all of which communicate in sequence by means of a microfluidic channel; a sample liquid driving device in sealed communication with the communication port by means of a sealed docking mechanism; and a detection mechanism for detecting the detection cell to obtain preset detection parameters of a sample liquid. The communication port is fixedly provided with a plug pin having an internal flow channel in sealed communication with the communication port, the plug pin is inserted into and forms a fluid-tight connection with the sealed docking mechanism, and the sealed docking mechanism is in fluid-tight connection with the sample liquid driving device, so that the sample liquid driving device is in sealed communication with the communication port.

First claim

What is claimed is:

1 . A microfluidic detection system for a refrigerator, comprising:
a microfluidic biochip that has a sample inlet, a communication port and a detection pool formed therein, wherein the sample inlet, the detection pool and the communication port communicate in sequence by means of a microfluidic channel; a sample liquid driving device, which is in sealed communication with the communication port by means of a sealed docking mechanism, and is used to impel sample liquid in contact with the sample inlet to enter the microfluidic channel and flow to the detection pool by means of the microfluidic channel; and a detection mechanism, which is used for detecting the detection pool so as to obtain a preset detection parameter of the sample liquid, wherein the communication port of the microfluidic biochip is fixedly provided with a plug pin protruding and extending outward, an internal flow channel of the plug pin is in sealed communication with the communication port, and the plug pin is inserted into the inside of the sealed docking mechanism and forms a fluid-tight connection with the sealed docking mechanism, and the sealed docking mechanism is in fluid-tight connection with the sample liquid driving device, so that the sample liquid driving device is in sealed communication with the communication port; wherein the sealed docking mechanism is connected between the microfluidic biochip and the sample liquid driving device, a through channel penetrating through the sealed docking mechanism is formed in the sealed docking mechanism, and the sample liquid driving device and the communication port are both communicated with the through channel; and wherein the sample liquid driving device is provided with a connecting pipeline connected with the sealed docking mechanism, the sealed docking mechanism comprises a first connecting piece and a second connecting piece which are sequentially arranged between the sample liquid driving device and the microfluidic biochip, a first connecting column and a second connecting column protruding and extending in opposite directions are formed on two opposite sides of the first connecting piece respectively, the first connecting column is inserted into the connecting pipeline, the second connecting column is inserted into the second connecting piece, and the plug pin is in insertion-connection with the second connecting piece.

2 . The microfluidic detection system according to claim 1 ,
wherein an end surface of an extended tip of the plug pin is a continuous and smooth hemispherical surface, and a pin hole of the plug pin for fluid communication with the sealed docking mechanism is formed on the circumferential side of a section of the plug pin located inside the sealed docking mechanism.

3 . The microfluidic detection system according to claim 1 ,
wherein a sealing ring for abutting contact or pressing contact with the plug pin is formed on the sealed docking mechanism, a through hole for the plug pin to pass through is formed in the middle of the sealing ring, and a sealing reinforcing rib protruding towards the radial inner side of the through hole is formed on the circumferential wall of the through hole.

4 . The microfluidic detection system according to claim 1 ,
wherein the outer wall of an end section of the plug pin for insertion into the sealed docking mechanism is tapered in an insertion direction of the plug pin; and the pin hole of the plug pin for fluid communication with the sealed docking mechanism is formed on the end surface of the extended tip of the plug pin.

5 . The microfluidic detection system according to claim 1 ,
wherein the plug pin is inserted into the microfluidic biochip through the communication port, and a starting end of the plug pin extending into the microfluidic biochip is open; and a matching interface between the plug pin and the communication port is sealed by sealing gum.

6 . The microfluidic detection system according to claim 1 , further comprising:
a chip mounting mechanism for fixing the microfluidic biochip after the plug pin and the sealed docking mechanism form a fluid-tight connection, such that the microfluidic biochip keeps a state of fluid-tight connection with the sample liquid driving device; and an elastic pressing mechanism for applying an elastic acting force to the sealed docking mechanism, such that the sealed docking mechanism is elastically and hermetically docked with the sample liquid driving device and the microfluidic biochip at the same time.

7 . The microfluidic detection system according to claim 6 ,
wherein the elastic pressing mechanism is a spring, one end of the spring abuts against a fixedly arranged end plate, the other end of the spring abuts against the sealed docking mechanism, and the end plate and the microfluidic biochip are located on two opposite sides of the sealed docking mechanism respectively, such that the spring generates the elastic acting force towards the microfluidic biochip on the sealed docking mechanism.

8 . The microfluidic detection system according to claim 7 , further comprising:
a guide rod sleeved with the spring; wherein one end of the guide rod is fixedly connected with the sealed docking mechanism, and the other end of the guide rod is in contact with a Hall switch after the plug pin and the sealed docking mechanism form the fluid-tight connection, such that the Hall switch is prompted to generate a trigger signal for indicating that the microfluidic biochip is mounted in place.

9 . The microfluidic detection system according to claim 6 ,
wherein the chip mounting mechanism comprises two oppositely arranged elastic clamping jaws, so as to apply opposite acting forces to the microfluidic biochip clamped between the two elastic clamping jaws; and the microfluidic detection system further comprises a cantilever button which is suspended on one side of the microfluidic biochip, the cantilever button abuts against the inner sides of the two elastic clamping jaws at the same time, and acting forces which promote the elastic clamping jaws to elastically deform in directions of departing from each other are applied to the two elastic clamping jaws when the cantilever button is subjected to acting forces towards the elastic clamping jaws, so as to relieve the clamping effect of the two elastic clamping jaws on the microfluidic biochip.

10 . The microfluidic detection system according to claim 1 , further comprising:
a sample stage for placing a sample cup, the sample cup being used for containing sample liquid; wherein the sample stage comprises a support stage for supporting the sample cup and an oscillator provided on the support stage, and the oscillator is used for oscillating the sample cup after the sample cup is placed on the support stage, such that buffer liquid and a sample in the sample cup are fully mixed to generate the sample liquid.

11 . A refrigerator comprising the microfluidic detection system according to claim 1 .

12 . A microfluidic detection system for a refrigerator, comprising:
a microfluidic biochip that has a sample inlet, a communication port and a detection pool formed therein, wherein the sample inlet, the detection pool and the communication port communicate in sequence by means of a microfluidic channel; a sample liquid driving device, which is in sealed communication with the communication port by means of a sealed docking mechanism, and is used to impel sample liquid in contact with the sample inlet to enter the microfluidic channel and flow to the detection pool by means of the microfluidic channel; and a detection mechanism, which is used for detecting the

Assignees

• Qingdao haier refrigerator co ltd
• Haier Smart Home Co Ltd

Inventors

• Fei Bin
• Liu Haoquan
• Wang Jing
• Zhao Bintang

Classifications

• F25D23/028

  Details · CPC title

• B01L2300/0819

  Microarrays; Biochips · CPC title

• B01L2200/0689

  Sealing · CPC title

• B01L2200/027

  for microfluidic devices · CPC title

• G01N33/02

  Food · CPC title