Chemical wake-up mechanism for active electronics in pen injectors

Patent metadata

Field	Value
Publication number	US-12533465-B2
Application number	US-202017621557-A
Country	US
Kind code	B2
Filing date	Jun 25, 2020
Priority date	Jul 1, 2019
Publication date	Jan 27, 2026
Grant date	Jan 27, 2026

Abstract

Implementations of the present disclosure are directed to conserving energy of an injection device that includes an energy source configured to power an electronic component, a priming component configured to generate a trigger, a reactant configured to generate an instantiation signal in response to the trigger, and a sensor configured to detect and process the instantiation signal and generate an activation signal to activate the energy source.

First claim

The invention claimed is:

1 . An injection device comprising:
an energy source configured to power an electronic component; a priming component configured to convert a mechanical impulse into a trigger; a plunger configured to transmit the trigger from the priming component to a bearing; the bearing configured to provide firm mounting to an end of the plunger; a reactant included in the bearing and configured to initiate a thermochemical reaction that generates an instantiation signal transmittable through the bearing in response to receiving the trigger; and a sensor configured to detect and process the instantiation signal and generate an activation signal to activate the energy source, the activation signal comprising a wakeup signal to power the electronic component of the injection device.

2 . The injection device of claim 1 , wherein the reactant is configured to shift from a first position to a second position to generate the instantiation signal.

3 . The injection device of claim 1 , wherein the sensor is included in a plunger stopper.

4 . The injection device of claim 1 , wherein the plunger is configured to transmit the trigger to the reactant.

5 . The injection device of claim 1 , wherein the instantiation signal comprises a thermic signal and the reactant comprises two reactants configured to generate an exothermic reaction in response to the trigger.

6 . The injection device of claim 5 , wherein the sensor comprises a temperature sensor.

7 . The injection device of claim 6 , wherein the temperature sensor comprises a first temperature sensor configured to detect the thermic signal generated by the two reactants.

8 . The injection device of claim 7 , wherein the temperature sensor comprises a second temperature sensor configured to detect a temperature of a medicament stored in a medicament reservoir.

9 . The injection device of claim 8 , wherein the activation signal is based on a temperature difference between the medicament and the exothermic reaction.

10 . The injection device of claim 1 , wherein the instantiation signal comprises a photo-signal and the reactant comprises one or more reactants configured to generate a luminescent reaction in response to the trigger.

11 . The injection device of claim 10 , wherein the sensor comprises a photoelectric sensor.

12 . The injection device of claim 11 , wherein the photoelectric sensor comprises a first photoelectric sensor configured to detect a photoemission generated by the luminescent reaction.

13 . The injection device of claim 1 , wherein the reactant comprises a first reactant and a second reactant, at least one of the first reactant and the second reactant comprising a fluid reactant, the first reactant and the second reactant being separated from each other by a fluid impermeable membrane that is configured to be pierced in reaction to the trigger to enable interaction between the first reactant and the second reactant.

14 . The injection device of claim 1 , wherein the reactant comprises a first solid reactant and a second solid reactant that is distanced from the first solid reactant in a pre-priming configuration and is configured to be mechanically coupled to the first solid reactant in reaction to the trigger to enable interaction between the first solid reactant and the second solid reactant.

15 . A medicament injection system comprising:
an injection device comprising:
an energy source configured to power an electronic component,
a priming component configured to convert a mechanical impulse into a trigger,
a plunger configured to transmit the trigger from the priming component to a bearing,
the bearing configured to provide firm mounting to an end of the plunger,
a reactant included in the bearing and configured to initiate a thermochemical reaction that generates an instantiation signal transmittable through the bearing in response to receiving the trigger, and
a sensor configured to detect and process the instantiation signal and generate an activation signal to activate the energy source, the activation signal comprising a wakeup signal to power the electronic component of the injection device; and
an external device comprising an external processor configured to communicate with the injection device.

16 . The medicament injection system of claim 15 , wherein the sensor is included in a plunger stopper and the sensor comprises a temperature sensor.

17 . The medicament injection system of claim 15 , wherein the external device is configured to receive and display operational data and treatment data from the injection device.

18 . A method for powering an injection device, the method comprising:
converting, by a priming component, a mechanical impulse into a trigger; transmitting, by a plunger, the trigger from the priming component to a bearing; initiating, by a reactant included in the bearing, a thermochemical reaction that generates an instantiation signal; transmitting, through the bearing, the instantiation signal; detecting, by a sensor, the instantiation signal; processing, by the sensor, the instantiation signal to generate an activation signal; and transmitting, by the sensor, the activation signal to an energy source, the activation signal comprising a wakeup signal to power an electronic component of the injection device.

19 . The method of claim 18 , further comprising:
transmitting operational data to an external device, the operational data comprising one or more of a time of start of usage of the injection device and a temperature of the injection device during use and storage.

20 . The method of claim 18 , further comprising:
transmitting treatment data to an external device, the treatment data comprising one or more of an amount of medicament dispensed by the injection device and a time the medicament was dispensed by the injection device.

Assignees

• Sanofi Sa

Inventors

• Schabbach Michael
• Alpers Johannes
• Vedhachalam Ganesh Appusamy
• Bigalke Jörg
• Rausch Martin
• Baccaro Anna

Classifications

• A61M2205/8275

  Mechanical · CPC title

• A61M2205/82

  Internal energy supply devices · CPC title

• A61M2205/502

  User interfaces, e.g. screens or keyboards · CPC title

• A61M2205/50

  with microprocessors or computers · CPC title

• A61M2205/3368

  Temperature · CPC title