Methods, devices, and systems for providing peritoneal dialysis fluid from powdered concentrate

Patent metadata

Field	Value
Publication number	US-12533449-B2
Application number	US-202017778286-A
Country	US
Kind code	B2
Filing date	Nov 17, 2020
Priority date	Nov 20, 2019
Publication date	Jan 27, 2026
Grant date	Jan 27, 2026

Abstract

A proportioning system includes a solute container filled with dry solutes, a source of water, a container of electrolyte concentrate, a fluid circuit connecting the solute container to the source of water and the container of electrolyte concentrate, the fluid circuit having an empty mixing container, a controller configured to transfer water from the source of water to the solute container through the fluid circuit so as to prepare a solute concentrate solution in the solute container. The controller is configured to transfer fluid from the container of electrolyte concentrate to a mixing container as well as a solute concentrate from the solute container to the mixing container and further adding water to said mixing container to form a medicament therein.

First claim

What is claimed is:

1 . A proportioning system, comprising:
a solute container filled with dry solutes and having at least an inlet port and an outlet port;
a source of purified water;
a container of electrolyte concentrate;
a fluid circuit connecting the inlet port of the solute container and the outlet port of the solute container to the source of water and to the container of electrolyte concentrate, the fluid circuit being fluidly connected to an empty mixing container;
a plurality of controllable clamps that open and close flow in portions of the fluid circuit;
a peristaltic pump configured to pump fluid through the fluid circuit; and
a controller configured to open and close the controllable clamps and to control the peristaltic pump, wherein
the controller is further configured to open a first controllable clamp and a second controllable clamp to thereby transfer purified water from the source of purified water to the inlet port of the solute container through the fluid circuit while accounting for residual water in tube lengths that form a circulating path between the inlet port of the solute container and the outlet port of the solute container,
the controller is further configured to, after the transferring, open the second controllable clamp, close all other controllable clamps, and control the peristaltic pump to rotate in a first direction to thereby circulate a mixture of the purified water and the dry solutes out of the outlet port of the solute container and into the inlet port of the solute container so as to prepare a solute concentrate solution in the solute container,
the controller is further configured to, after the circulating the mixture of the purified water and the dry solutes, control the peristaltic pump to rotate in a second direction, opposite to the first direction, to thereby transfer a fluid from the container of electrolyte concentrate to the mixing container and as well as a liquid solute concentrate from the solute container to the mixing container, and
the controller is further configured to add purified water to the mixing container to form a medicament in the mixing container.

2 . The system of claim 1 , wherein the dry solutes include at least one of dextrose monohydrate and sterile dextrose powder.

3 . The system of claim 1 , wherein the controller is configured to control the proportioning system to mix the water and dry solutes in said solute container using a pump to flow the water through at least a portion of the fluid circuit.

4 . The system of claim 1 , further comprising a water pump configured to pump water through a water filter and then into the fluid circuit.

5 . The system of claim 1 , further comprising a fluid consuming device with a pump and said mixing container.

6 . A proportioning method, comprising:
providing a solute container that has an inlet port and an outlet port and filled with dry solutes; providing a fluid circuit; connecting a source of purified water to the fluid circuit; providing a container of electrolyte concentrate; connecting the fluid circuit to the inlet port of the solute container, to the outlet port of the solute container, to the source of purified water, and to the container of electrolyte concentrate, the fluid circuit being fluidly connected to an empty mixing container; using a controller to open a first controllable clamp and a second controllable clamp to thereby transfer purified water from the source of purified water to the inlet port of the solute container through the fluid circuit while accounting for residual water in tube lengths that form a circulating path between the inlet port of the solute container and the outlet port of the solute container; after the transferring, opening the second controllable clamp, closing all other controllable clamps, and controlling a peristaltic pump to rotate in a first direction to thereby circulate a mixture of the purified water and the dry solutes out of the outlet port of the solute container and into the inlet port of the solute container so as to prepare a solute concentrate solution in the solute container; after preparing the solute concentrate solution, controlling the peristaltic pump to rotate in a second direction, opposite to the first direction, to thereby transfer a fluid from the container of electrolyte concentrate to the mixing container and to transfer the solute concentrate solution from the solute container to the mixing container; and using the controller, adding purified water to the mixing container and mixing contents of the mixing container to form a medicament in the mixing container.

7 . The proportioning method of claim 6 , wherein the dry solutes include at least one of dextrose monohydrate and sterile dextrose powder.

8 . The proportioning method of claim 6 , wherein the transferring of purified water from the source of purified water to the solute container includes activating a water pump configured to pump the purified water through a water filter and then into the fluid circuit.

9 . The proportioning method of claim 6 , wherein the mixing container is a part of a fluid consuming device with a pump.

Assignees

• Nxstage Medical Inc

Inventors

• Wyeth Mark T

Classifications

• A61M1/287

  Dialysates therefor · CPC title

• A61M1/1672

  using membrane filters, e.g. for sterilising the dialysate · CPC title

• A61M1/1666 Primary

  by dissolving solids · CPC title

• A61M1/1601

  Control or regulation · CPC title

• A61M1/1656 Primary

  Apparatus for preparing dialysates · CPC title