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Kit or device and method for detecting dementia
US12529104B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12529104-B2 |
| Application number | US-201916969328-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 12, 2019 |
| Priority date | Feb 13, 2018 |
| Publication date | Jan 20, 2026 |
| Grant date | Jan 20, 2026 |
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- Title
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Abstract
Official abstract text for this publication.
An embodiment according to the present invention provides a kit or device for detection of dementia, and a method for detecting dementia. An embodiment according to the present invention relates to: a kit or device for detection of dementia, including a nucleic acid(s) capable of specifically binding to an miRNA(s) or a complementary strand(s) thereof in a sample from a subject; and a method for detecting dementia, including measuring the miRNA(s) in vitro.
First claim
Opening claim text (preview).
The invention claimed is: 1 . A method for detecting dementia, comprising measuring expression levels of the polynucleotides of dementia markers: miR-6088 and miR-211-5p in a sample from a subject; and evaluating in vitro whether or not the subject has dementia using the measured expression levels of only miR-6088 and miR-211-5p. 2 . The method according to claim 1 , comprising plugging the gene expression levels of the polynucleotides in the sample from the subject into a discriminant formula capable of discriminating dementia or non-dementia distinctively, wherein the discriminant formula is created by using gene expression levels in samples from subjects known to have dementia and gene expression levels in samples from non-dementia subjects as training samples; and thereby evaluating whether or not the subject has dementia. 3 . The method according to claim 1 , wherein the expression levels of the target genes in the sample from the subject are measured by using a kit for detection of dementia, comprising nucleic acids capable of specifically binding polynucleotides of dementia markers: or to complementary strands of the polynucleotides. 4 . The method according to claim 1 , the subject is a human. 5 . The method according to claim 1 , the sample is blood, serum, or plasma.
Assignees
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Classifications
Expression markers · CPC title
Hybridisation assays · CPC title
Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection · CPC title
miRNA, siRNA or ncRNA · CPC title
- C12Q1/6883Primary
for diseases caused by alterations of genetic material · CPC title
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Frequently asked questions
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- What does patent US12529104B2 cover?
- An embodiment according to the present invention provides a kit or device for detection of dementia, and a method for detecting dementia. An embodiment according to the present invention relates to: a kit or device for detection of dementia, including a nucleic acid(s) capable of specifically binding to an miRNA(s) or a complementary strand(s) thereof in a sample from a subject; and a method fo…
- Who is the assignee on this patent?
- Toray Industries, Nat Ct Geriatrics & Gerontology
- What technology area does this patent fall under?
- Primary CPC classification C12Q1/6883. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Jan 20 2026 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 4 related publications on this page (citations in our corpus or others sharing the same primary CPC).