Device for measuring pressure in an extracorporeal blood circuit

Patent metadata

Field	Value
Publication number	US-12514964-B2
Application number	US-202017775344-A
Country	US
Kind code	B2
Filing date	Nov 12, 2020
Priority date	Nov 13, 2019
Publication date	Jan 6, 2026
Grant date	Jan 6, 2026

Abstract

A method for referencing a pressure or force sensor configured to measure pressure in a tube filled with fluid. The pressure or force sensor is located in an extracorporeal circuit and integrated into or inserted in a clamping device The method includes: (1) referencing a force or pressure reference signal which the pressure or force sensor outputs, with a force or pressure reference signal measured by a force or pressure reference sensor; and (2) using a dialysis fluid side force or pressure reference sensor in a dialysis fluid circuit configured to detect the pressure in the dialysis fluid circuit, for referencing a pressure sensor or force sensor in the extracorporeal circuit. A device uses a dialysis fluid side force or pressure reference sensor in the dialysis fluid circuit that detects pressure in the dialysis fluid circuit, for referencing at least one pressure or force sensor in the extracorporeal circuit.

First claim

The invention claimed is:

1 . A method for calibrating at least one pressure or force sensor, which is configured to measure a tube internal pressure in an extracorporeal circuit tube, which is filled with fluid, wherein the at least one pressure or force sensor is integrated into or inserted in a clamping device, the method comprising:
locating the at least one pressure or force sensor in an extracorporeal circuit of a dialysis machine; locating at least one dialysis fluid side force or pressure reference sensor in a dialysis fluid circuit of the dialysis machine, wherein the at least one dialysis fluid side force or pressure reference sensor is not provided in a clamping device; receiving a pressure or force signal from the at least one pressure or force sensor; receiving a dialysis tube internal pressure in the dialysis fluid circuit from the at least one dialysis fluid side force or pressure reference sensor; and calibrating the pressure or force signal from the at least one pressure or force sensor based on the received dialysis tube internal pressure in the dialysis fluid circuit; wherein the dialysis machine comprises a dialyzer having a semipermeable filter membrane between the extracorporeal circuit and the dialysis fluid circuit, and the at least one dialysis fluid side force or pressure reference sensor is arranged on a dialysis fluid inlet tube of the dialyzer, or on a dialysis fluid outlet tube of the dialyzer; wherein the method further comprises:
providing a bypass operation in which a dialysis fluid in the dialysis fluid circuit does not flow through the dialyzer but does flow through a bypass line, and a main connection operation in which the dialysis fluid flows through the dialyzer,
switching from the main connection operation to the bypass operation, and
waiting for a predetermined period of time to allow a pressure equalization to occur in the dialyzer between the dialysis fluid circuit and the extracorporeal circuit across the semipermeable filter membrane of the dialyzer before calibrating the pressure or force signal.

2 . The method according to claim 1 wherein:
the at least one pressure or force sensor comprises a venous pressure or force sensor arranged on a venous section of the extracorporeal circuit tube downstream of the dialyzer.

3 . The method according to claim 2 , wherein the at least one dialysis fluid side force or pressure sensor is arranged on the dialysis fluid outlet tube of the dialyzer, and the method further comprises:
operating a pump which delivers extracorporeal fluid through the extracorporeal circuit tube; and after waiting the predetermined period of time, and while operating the pump which delivers extracorporeal fluid through the extracorporeal circuit tube, calibrating the pressure or force signal from the venous pressure or force sensor via the at least one dialysis fluid side force or pressure reference sensor arranged on the dialysis fluid outlet tube.

4 . The method according to claim 2 , further comprising:
stopping a pump which delivers extracorporeal fluid through the extracorporeal circuit tube; after waiting the predetermined period of time, closing a venous tube clamp which is a tube clamp in a venous section of the extracorporeal circuit tube; and calibrating the pressure or force signal from the venous pressure or force sensor via the at least one dialysis fluid side force or pressure reference sensor.

5 . The method according to claim 1 , further comprising, as part of calibrating the pressure or force signal from the at least one pressure or force sensor with the received dialysis tube internal pressure in the dialysis fluid circuit:
carrying out a dialyzer specific referencing in order to take into account an influence of the dialyzer; and/or taking into account a pulsation of pump roller rotors of a fluid conveying pump; and/or taking into account influencing variables, which cause an offset deviation of pressure curves.

Assignees

• Braun Avitum Ag
• Braun Avitum Ag

Inventors

• Wolff Henrik
• Wuerschmidt Tobias

Classifications

• A61M2205/702

  automatically during use · CPC title

• A61M2205/3331

  Pressure; Flow · CPC title

• A61M2205/332

  Force measuring means · CPC title

• A61M2205/3362

  with minimised length of fluid lines; Taking into account the elastic expansion of fluid lines to increase accuracy · CPC title

• A61M2209/082

  Mounting brackets, arm supports for equipment · CPC title