Pyrazole pyrimidine derivative and uses thereof

US12514859B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-12514859-B2
Application numberUS-202418432931-A
CountryUS
Kind codeB2
Filing dateFeb 5, 2024
Priority dateAug 4, 2015
Publication dateJan 6, 2026
Grant dateJan 6, 2026

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The present invention provides pyrazole pyrimidine derivatives which inhibit Casein kinase I (CKI) and/or Interleukin-1 receptor-associated kinase 1 (IRAKI) and methods of their manufacture, compositions comprising them and uses thereof in methods of treating malignant disease and disorders and methods for treating inflammatory diseases and disorders.

First claim

Opening claim text (preview).

The invention claimed is: 1 . A compound having the formula: or a pharmaceutically acceptable salt thereof. 2 . A compound having the formula: or a pharmaceutically acceptable salt thereof. 3 . A compound having the formula: or a pharmaceutically acceptable salt thereof.

Assignees

Inventors

Classifications

  • specific for leukemia · CPC title

  • C07D403/04Primary

    directly linked by a ring-member-to-ring-member bond · CPC title

  • containing three or more hetero rings · CPC title

  • containing three or more hetero rings · CPC title

  • containing three or more hetero rings · CPC title

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Frequently asked questions

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What does patent US12514859B2 cover?
The present invention provides pyrazole pyrimidine derivatives which inhibit Casein kinase I (CKI) and/or Interleukin-1 receptor-associated kinase 1 (IRAKI) and methods of their manufacture, compositions comprising them and uses thereof in methods of treating malignant disease and disorders and methods for treating inflammatory diseases and disorders.
Who is the assignee on this patent?
Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd
What technology area does this patent fall under?
Primary CPC classification C07D403/04. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Jan 06 2026 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 4 related publications on this page (citations in our corpus or others sharing the same primary CPC).