Pyrazole compounds and uses thereof
US-11072599-B2 · Jul 27, 2021 · US
US12514859B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12514859-B2 |
| Application number | US-202418432931-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 5, 2024 |
| Priority date | Aug 4, 2015 |
| Publication date | Jan 6, 2026 |
| Grant date | Jan 6, 2026 |
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The present invention provides pyrazole pyrimidine derivatives which inhibit Casein kinase I (CKI) and/or Interleukin-1 receptor-associated kinase 1 (IRAKI) and methods of their manufacture, compositions comprising them and uses thereof in methods of treating malignant disease and disorders and methods for treating inflammatory diseases and disorders.
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The invention claimed is: 1 . A compound having the formula: or a pharmaceutically acceptable salt thereof. 2 . A compound having the formula: or a pharmaceutically acceptable salt thereof. 3 . A compound having the formula: or a pharmaceutically acceptable salt thereof.
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containing three or more hetero rings · CPC title
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