Controlled release antimicrobial compositions and methods for the treatment of otic disorders
US-2018161271-A1 · Jun 14, 2018 · US
US12508247B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12508247-B2 |
| Application number | US-202017763205-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 30, 2020 |
| Priority date | Oct 1, 2019 |
| Publication date | Dec 30, 2025 |
| Grant date | Dec 30, 2025 |
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The present invention relates to a controlled release injectable ondansetron formulation comprising ondansetron or pharmaceutically acceptable salt, derivative or metabolite thereof which releases ondansetron over a period of at least 2 days period from the date of administration and the process for preparation thereof.
Opening claim text (preview).
We claim: 1 . A controlled release injectable ondansetron formulation consisting of (a) 20 mg/mL to 180 mg/mL ondansetron, (b) 1 mg/mL to 15 mg/mL carboxymethyl cellulose or its sodium salt, (c) 1 mg/mL to 15 mg/mL phosphatidyl choline, (d) ethanol and (e) water.
Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin (homeopathic globules A61K9/1623) · CPC title
comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers (lipids as modifying agents {A61K47/543}) · CPC title
Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner (non-active ingredients are additionally classified in A61K47/00) · CPC title
containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids · CPC title
Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers · CPC title
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