Electrophoresis device

Patent metadata

Field	Value
Publication number	US-12498348-B2
Application number	US-202018008461-A
Country	US
Kind code	B2
Filing date	Jun 26, 2020
Priority date	Jun 26, 2020
Publication date	Dec 16, 2025
Grant date	Dec 16, 2025

Abstract

An electrophoresis device of the present disclosure includes: a capillary filled with a phoresis medium; a buffer container accommodating a buffer solution; a storage portion storing a sample container accommodating a sample; at least one autosampler transporting each of the sample container and the buffer container; and a control unit controlling driving of the autosampler, in which the control unit drives the autosampler such that, while the buffer container is disposed at a capillary position where one end portion of the capillary is positioned, the sample container is transported from the storage portion to a standby position near the capillary position, and, when the buffer container has been transported from the capillary position to the standby position, the sample container is transported from the standby position to the capillary position.

First claim

The invention claimed is:

1 . An electrophoresis device comprising:
a capillary filled with a phoresis medium; a buffer container accommodating a buffer solution; a storage portion storing a sample container accommodating a sample; a sample autosampler transporting the sample container; a buffer autosampler transporting the buffer container; and a computer configured to control driving of the autosampler, wherein the computer is configured to: control driving of the sample autosampler to transport the sample container between the storage portion, a standby position, and a capillary position, and to control driving of the buffer autosampler to transport the buffer container between the capillary position and the standby position, control the sample autosampler to, while the buffer container is disposed at the capillary position where one end portion of the capillary is positioned, transport the sample container from the storage portion to the standby position near the capillary position, and control the sample autosampler and buffer autosampler to, when the buffer container has been transported from the capillary position to the standby position, transport the sample container from the standby position to the capillary position.

2 . The electrophoresis device according to claim 1 ,
wherein the computer is configured to: control the sample autosampler to start the transport of the sample container after the capillary is filled with the phoresis medium, and control the sample autosampler to withdraw the sample container from the capillary position after the sample container is transported to the capillary position and the sample is injected into the capillary and before electrophoresis is started.

3 . The electrophoresis device according to claim 1 ,
wherein the sample autosampler is driven within a first region of movement and the buffer autosampler is driven within a second region of movement, which is different than the first region of movement except for the capillary position where the first region of movement and the second region of moment overlap.

4 . The electrophoresis device according to claim 1 ,
wherein the control unit locks the storage portion when the sample autosampler is not at a predetermined position and unlocks the storage portion when the sample autosampler is at the predetermined position.

5 . The electrophoresis device according to claim 1 , further comprising:
a barcode reader, wherein information on the sample is marked on the sample container, and wherein the computer is configured to drive the sample autosampler so as to transport the sample container from the storage portion to a reading position of the barcode reader.

6 . The electrophoresis device according to claim 5 ,
wherein the storage portion has a sensor detecting presence or absence of the sample container, and wherein when the sensor detects that the sample container has been disposed, the computer is configured to drive the sample autosampler to transport the sample container from the storage portion to the reading position, and read the information on the sample based on a read signal of the barcode reader.

7 . The electrophoresis device according to claim 6 ,
wherein the storage portion includes a plurality of storage positions, wherein the sensor is provided at each of the plurality of storage positions, and wherein the computer is configured to drive the sample autosampler to transport the sample container to the reading position from the storage position where the sensor has detected that the sample container has been disposed.

8 . The electrophoresis device according to claim 1 ,
wherein the computer is configured to simultaneously drive the sample autosampler and the buffer autosampler at a predetermined timing.

9 . An electrophoresis device comprising:
a capillary filled with a phoresis medium; a buffer container accommodating a buffer; a storage portion storing a sample container accommodating a sample; a sample autosampler transporting the sample container; a buffer autosampler transporting the buffer container; a barcode reader configured to read information on the sample marked on the sample container; and a computer configured to control the sample autosampler and buffer autosampler, wherein the computer is configured to: drive the sample autosampler to transport the sample container from the storage portion to a reading position of the barcode reader drive the buffer autosampler to transport the buffer container between the capillary position where one end portion of the capillary is positioned and the standby position near the capillary position, and drive the sample autosampler to transport the sample container between the storage portion, the standby position, and the capillary position.

10 . The electrophoresis device according to claim 9 ,
wherein the storage portion has a sensor detecting presence or absence of the sample container, and wherein the computer is configured to, when the sensor detects that the sample container has been disposed, drive the sample autosampler to transport the sample container from the storage portion to the reading position, and read the information on the sample based on a read signal of the barcode reader.

11 . The electrophoresis device according to claim 10 ,
wherein the storage portion includes a plurality of storage positions, wherein the sensor is provided at each of the plurality of storage positions, and wherein the computer is configured to drive the sample autosampler to transport the sample container to the reading position from a storage position, among the plurality of storage positions, where the sensor has detected that the sample container has been disposed.

12 . The electrophoresis device according to claim 9 , further comprising:
a buffer autosampler configured to transport a buffer container accommodating a buffer.

Assignees

• Hitachi High Tech Corp

Inventors

• Noda Kazuki
• Ooura Takeshi
• KARIYA Shunichi

Classifications

• G01N27/44791

  Microapparatus (sample containers with integrated microfluidic structures B01L3/5027) · CPC title

• G01N27/44704 Primary

  Details; Accessories · CPC title

• G01N27/447 Primary

  using electrophoresis · CPC title