Methods for lowering the incidence of hemorrhagic heart disease in swine

Patent metadata

Field	Value
Publication number	US-12497650-B2
Application number	US-202217690796-A
Country	US
Kind code	B2
Filing date	Mar 9, 2022
Priority date	Mar 10, 2021
Publication date	Dec 16, 2025
Grant date	Dec 16, 2025

Abstract

The invention encompasses methods for reducing the incidence of hemorrhagic heart disease in livestock.

First claim

I claim:

1 . A method of reducing the incidence of Mulberry heart disease in a Sus scrofa population comprising:
identifying selection candidates in the population; for each selection candidate, determining i) an allele of a single nucleotide polymorphism corresponding to position 204959669 of chromosome 13 of Sus scrofa , or ii) an allele of a genetic marker in linkage disequilibrium with the single nucleotide polymorphism wherein the allele of the genetic marker in linkage disequilibrium with the single nucleotide polymorphism is perfectly predictive of an allele of the single nucleotide polymorphism; selecting parents from among the selection candidates based on the determined allele of the single nucleotide polymorphism or based on the determined allele of the genetic marker in linkage disequilibrium with the single nucleotide polymorphism in the population; and producing progeny from the parents.

2 . The method of claim 1 , further comprising the step of correlating the determined allele of the single nucleotide polymorphism or the determined allele of the genetic marker with the risk of Mulberry heart disease in the individual.

Assignees

• Inguran Llc

Inventors

• Do Amaral Grossi Daniela

Classifications

• C12Q1/6883 Primary

  for diseases caused by alterations of genetic material · CPC title

• A01K2227/108

  Swine · CPC title

• A01K67/02

  Breeding vertebrates · CPC title

• C12Q1/6858

  Allele-specific amplification · CPC title

• C12Q2600/156

  Polymorphic or mutational markers · CPC title