Devices and methods for endoluminal delivery of either fluid or energy for denervation

Patent metadata

Field	Value
Publication number	US-12496469-B2
Application number	US-202117406822-A
Country	US
Kind code	B2
Filing date	Aug 19, 2021
Priority date	Nov 13, 2012
Publication date	Dec 16, 2025
Grant date	Dec 16, 2025

Abstract

Described herein are methods and devices for selectively applying either fluids (e.g., anesthetics, nerve-blockers, etc.) or energy, such as radiofrequency or ultrasound energy, to a target tissue from within a blood vessel while minimizing the amount of fluid or energy applied to non-target tissue. The catheters described herein may include an elongate body, a directional injector, and one or more holdfasts for securing the catheter. In addition, catheters can include energy applying features for delivering energy to the target tissue.

First claim

What is claimed:

1 . A catheter device, comprising:
an elongate body having a distal end and a proximal end; a passageway extending along a part of the elongate body, the passageway including an opening positioned adjacent the distal end and along an outer wall of the elongate body; and an injector slidably engaged with the passageway and configured to extend through the opening and penetrate tissue of a carotid artery; an ejectable holdfast including a plurality of flexible extensions, the plurality of flexible extensions expanding and extending from the distal end of the elongate body when ejected from the distal end of the elongate body, each flexible extension of the plurality of flexible extensions comprising a single length of flexible material that extends between a distal extension end and a proximal extension end, the proximal extension end being coupled to the elongate body, the plurality of flexible extensions radially expand and allow each distal extension end to contact inner walls of a carotid artery when the plurality of flexible extensions are ejected and extending from the distal end of the elongate body; and wherein the plurality of flexible extensions all have distal ends that are disposed distally of the distal end of the elongate body when the plurality of flexible extensions are ejected from the distal end of the elongate body.

2 . The catheter device of claim 1 , wherein each flexible extension of the plurality of flexible extensions includes a coating, the coating including a rubber material or a silicone material.

3 . The catheter device of claim 1 , wherein the injector includes a fluid pathway for delivering a fluid to a target area.

4 . The catheter device of claim 3 , wherein the fluid includes one or more of an anesthetic, a nerve-blocker, a drug, and a therapeutic.

5 . The catheter device of claim 3 , wherein the target area includes extraluminal space or tissue adjacent a carotid artery.

6 . The catheter device of claim 1 , wherein the injector includes a fluid dispensing feature that controls a direction the fluid is dispensed.

7 . The catheter device of claim 1 , wherein the elongate body includes an outer diameter that is sized to allow the elongate body to travel along a carotid artery.

8 . The catheter device of claim 1 , wherein the elongate body has a length suitable for treatment of a carotid body via a transcervical approach.

9 . The catheter device of claim 8 , wherein the length of the elongate body is within a range of approximately 40 centimeters to 80 centimeters.

10 . A method, comprising:
inserting at least a part of a catheter device into a vessel body, wherein the catheter device includes an elongate body having a distal end and a proximal end, the catheter device including a passageway extending along a part of the elongate body, the passageway including an opening positioned adjacent the distal end and along an outer wall of the elongate body, the catheter device including an injector slidably engaged with the passageway and configured to extend through the opening and penetrate tissue of a carotid artery, the catheter device including an ejectable holdfast including a plurality of flexible extensions, the plurality of flexible extensions expanding and extending from the distal end of the elongate body when ejected from the distal end of the elongate body, each flexible extension of the plurality of flexible extensions comprising a single length of flexible material that extends between a distal extension end and a proximal extension end, the proximal extension end being coupled to the elongate body, the plurality of flexible extensions configured to radially expand and allow each distal extension end to contact inner walls of a carotid artery when the plurality of flexible extensions are ejected and extending from the distal end of the elongate body; wherein the plurality of flexible extensions all have distal ends that are disposed distally of the distal end of the elongate body when the plurality of flexible extensions are ejected from the distal end of the elongate body; and radially expanding the plurality of flexible extensions to thereby enable the distal extension ends of the plurality of flexible extensions to contact an inner wall of a carotid artery and secure a position of the catheter device within a carotid artery.

11 . The method of claim 10 , further comprising:
advancing a distal end of the injector out of the opening and to a target area; and delivering a fluid from the injector to the target area.

12 . The method of claim 10 , wherein each flexible extension of the plurality of flexible extensions includes a coating, the coating including a rubber material or a silicone material.

13 . The method of claim 11 , wherein the injector includes a fluid pathway for delivering the fluid to a target area.

14 . The method of claim 11 , wherein the fluid includes one or more of an anesthetic, a nerve-blocker, a drug, and a therapeutic.

15 . The method of claim 11 , wherein the target area includes extraluminal space or tissue adjacent a carotid artery.

16 . The method of claim 11 , wherein the injector includes a fluid dispensing feature that controls a direction the fluid is dispensed.

17 . The method of claim 10 , wherein the elongate body includes an outer diameter that is sized to allow the elongate body to travel along a carotid artery.

18 . The method of claim 10 , wherein the elongate body has a length suitable for treatment of a carotid body via a transcervical approach.

19 . The method of claim 18 , wherein the length of the elongate body is within a range of approximately 40 centimeters to 80 centimeters.

20 . A catheter device, comprising:
an elongate body having a distal end and a proximal end; a passageway extending along a part of the elongate body, the passageway including an opening positioned adjacent the distal end and along an outer wall of the elongate body; and an injector slidably engaged with the passageway and configured to extend through the opening and penetrate tissue of a carotid artery; an ejectable holdfast including a plurality of flexible extensions, the plurality of flexible extensions expanding and extending from the distal end of the elongate body when ejected from the distal end of the elongate body, each flexible extension of the plurality of flexible extensions comprising a single length of flexible material that extends between a distal extension end and a proximal extension end, the proximal extension end being coupled to the elongate body, the plurality of flexible extensions radially expand and allow each distal extension end to contact inner walls of a carotid artery when the plurality of flexible extensions are ejected and extending from the distal end of the elongate body; wherein the plurality of flexible extension includes a first flexible extension having a first distal end; wherein the plurality of flexible extension includes a second flexible extension having a second distal end; wherein both the first distal end of the first flexible extension and the second distal end of the second distal extension are disposed distally of the distal end of the elongate body when the first flexible extension and the second flexible extension are ejected from the distal end of the elongate body.

Assignees

• Boston Scient Scimed Inc

Inventors

• Garrison Michi E
• Ruedy Richard M

Classifications

• A61B2017/22082

  after introduction of a substance · CPC title

• A61B2017/22067

  Blocking; Occlusion (A61B2017/22054 takes precedence) · CPC title

• A61B2017/22054

  with two balloons · CPC title

• A61B17/3478

  Endoscopic needles, e.g. for infusion (biopsy needles A61B10/0233; catheters with injection needles A61M25/0067) · CPC title

• A61B2218/002

  Irrigation · CPC title