Method for regulating blood glucose, losing weight, and reducing production of advanced glycation end products by using Saccharomyces cerevisiae TCI907 or supernatant thereof

Patent metadata

Field	Value
Publication number	US-12496322-B2
Application number	US-202418422022-A
Country	US
Kind code	B2
Filing date	Jan 25, 2024
Priority date	Aug 14, 2019
Publication date	Dec 16, 2025
Grant date	Dec 16, 2025

Abstract

Methods for regulating blood glucose, losing weight, or reducing production of advanced glycation end products comprising administering to a subject in need thereof a composition containing an effective amount of Saccharomyces cerevisiae TCI907 and/or a metabolite thereof. The Saccharomyces cerevisiae TCI907 is deposited at the German Collection of Microorganisms and Cell Cultures under an accession number of DSMZ33480.

First claim

What is claimed is:

1 . A method for regulating blood glucose of a subject comprising administering to the subject a composition comprising an effective amount of Saccharomyces cerevisiae TCI907 or supernatant thereof, wherein the Saccharomyces cerevisiae TC1907 is deposited at the German Collection of Microorganisms and Cell Cultures under an accession number of DSMZ33480, wherein the supernatant is obtained by the following steps: culturing the Saccharomyces cerevisiae TC1907 in a medium, centrifugating the cultured Saccharomyces cerevisiae TCI907 to separate the Saccharomyces cerevisiae TC1907 cells from a supernatant, thereby obtaining the supernatant.

2 . The method of claim 1 , wherein the Saccharomyces cerevisiae TC1907 or the supernatant thereof inhibits amylase activity to achieve the effect of regulating blood glucose.

3 . The method of claim 1 , wherein the Saccharomyces cerevisiae TCI907 depletes carbohydrates to achieve the effect of regulating blood glucose.

4 . The method of claim 1 , wherein the composition is in a capsule dosage form, and the effective amount of Saccharomyces cerevisiae TCI907 in the composition is 5×10 7 colony-forming unit/capsule (CFU/cap).

Assignees

• Tci Co Ltd

Inventors

• Huang Chu-Han
• Lin Yung-Hsiang

Classifications

• C12R2001/865

  Saccharomyces cerevisiae · CPC title

• C12N1/185

  Saccharomyces isolates · CPC title

• A61K35/66

  Microorganisms or materials therefrom (fungi, yeasts or candida A61K36/06) · CPC title

• A61P3/08

  for glucose homeostasis (pancreatic hormones A61P5/48) · CPC title

• A61P3/04 Primary

  Anorexiants; Antiobesity agents · CPC title