Systems and associated methods for improved interrogation of shunt functionality

Patent metadata

Field	Value
Publication number	US-12491348-B2
Application number	US-202017635641-A
Country	US
Kind code	B2
Filing date	Aug 17, 2020
Priority date	Aug 15, 2019
Publication date	Dec 9, 2025
Grant date	Dec 9, 2025

Abstract

Embodiments of a system for improved interrogation of shunt functionality are disclosed. The system includes a fluid flow detector having a microfluidic chamber configured for receiving the passage of bodily fluid flow. The fluid flow detector generates measurements and other data and provides wireless access to the same.

First claim

What is claimed is:

1 . A system for interrogating shunt functionality, comprising:
a fluid flow detector, comprising:
a microfluidic chamber including a microfluidic channel defining a fluid pathway through the microfluidic chamber for accommodating a bodily fluid therethrough, the microfluidic chamber including an inlet port defining a first lumen and an outlet port defining a second lumen, the second lumen being in fluid flow communication and orthogonal with the first lumen, and the first lumen including a pressure measurement passage located distal to a junction between the first lumen and the second lumen;
a pair of terminals positioned along the second lumen of the microfluidic chamber;
a pressure sensing pad having a membrane positioned within the pressure measurement passage of the microfluidic chamber, the membrane defining a surface normal that is parallel with a direction of elongation of the first lumen; and
a wireless chip;
wherein the fluid flow detector is configured to generate fluid flow measurements associated with changes in pressure and voltage using the pair of terminals and pressure sensing pad and provide access to the fluid flow measurements via a communication pathway using the wireless chip.

2 . The system of claim 1 , wherein the fluid flow detector is in fluid flow engagement with a shunt, and the fluid flow measurements are indicative as to functionality of the shunt.

3 . The system of claim 1 , wherein the inlet port is in fluid flow communication with one end of the fluid pathway and with cerebrospinal fluid associated with a surgical site, and wherein the fluid flow detector further comprises:
the outlet port in fluid flow communication with an opposite end of the fluid pathway.

4 . The system of claim 1 , wherein the fluid flow detector is configured to be implanted subcutaneously along an abdominal region of a patient.

5 . The system of claim 4 , wherein a position of the fluid flow detector relative to the patient is detectable via an X-ray apparatus.

6 . The system of claim 1 , wherein an electrical impedance of the microfluidic channel is determined using the pair of terminals.

7 . The system of claim 1 , wherein a voltage value is determined for each terminal of the pair of terminals.

8 . The system of claim 1 , wherein each terminal of the pair of terminals is in electrical communication with the fluid pathway of the microfluidic chamber.

9 . The system of claim 1 , wherein the fluid flow detector further comprises:
a wake up circuit in electrical communication with the wireless chip, the wake up circuit comprising a first magnetic element, wherein the wake up circuit activates the wireless chip when a second magnetic element is placed in proximity to the first magnetic element.

10 . A method, comprising:
providing a fluid flow detector comprising a microfluidic chamber, the microfluidic chamber having a microfluidic channel defining a fluid pathway through the microfluidic chamber, the microfluidic chamber including an inlet port defining a first lumen and an outlet port defining a second lumen, the second lumen being in fluid flow communication and orthogonal with the first lumen, and the first lumen including a pressure measurement passage located distal to a junction between the first lumen and the second lumen; measuring, by processor, an electrical impedance value exhibited by the microfluidic chamber associated with a fluid flow; measuring, by processor, a pressure value exerted on a pressure sensing pad having a membrane disposed within the pressure measurement passage of the microfluidic chamber, the membrane defining a surface normal that is parallel with a direction of elongation of the first lumen; providing access to the electrical impedance value and the pressure value by a communication pathway facilitated by a wireless communication module; and determining a flow state of a fluid within the microfluidic chamber using the electrical impedance value and the pressure value.

11 . The method of claim 10 , further comprising:
measuring a voltage value taken at a first terminal and a voltage value taken at a second terminal, wherein the first terminal is positioned at a first end of the microfluidic chamber in electrical communication with the fluid pathway and wherein the second terminal is positioned at an opposite second end of the microfluidic chamber in electrical communication with the fluid pathway.

12 . The method of claim 11 , further comprising:
identifying a flow state of the fluid within the microfluidic chamber using the voltage value taken at the first terminal and the voltage value taken at the second terminal, wherein a logic high voltage value is indicative of fluid within the fluid pathway contacting the first or second terminal and wherein a logic low voltage value is indicative of no fluid within the fluid pathway contacting the first or second terminal.

13 . The method of claim 10 , wherein the electrical impedance value of the microfluidic chamber is measured using a resistor coupled to the microfluidic chamber in a voltage divider configuration and wherein a voltage value measured across the resistor is used to infer the electrical impedance value of the microfluidic chamber.

14 . The method of claim 10 , further comprising:
assessing a dryness condition of an outlet port of the fluid flow detector using the measured electrical impedance value, wherein if a measured impedance value is within a range defined between an extreme low impedance value and an extreme high impedance value then the outlet port is in a wet condition and wherein if a measured impedance value is an extreme low impedance value or an extreme high impedance value then the outlet port is in a dry condition.

Assignees

• Dignity Health
• Texas A&M Univ

Inventors

• Porter Randall W
• Morgan Ii Clinton D
• Mooney Michael
• Park Sung Il

Classifications

• A61N1/205

  for promoting a biological process · CPC title

• A61B2562/0247

  Pressure sensors · CPC title

• A61B5/053

  Measuring electrical impedance or conductance of a portion of the body · CPC title

• A61B5/0031

  Implanted circuitry · CPC title

• A61B5/0022

  Monitoring a patient using a global network, e.g. telephone networks, internet · CPC title