Polymerizable absorbers of UV and high energy visible light

Patent metadata

Field	Value
Publication number	US-12486403-B2
Application number	US-202217809619-A
Country	US
Kind code	B2
Filing date	Jun 29, 2022
Priority date	Mar 2, 2018
Publication date	Dec 2, 2025
Grant date	Dec 2, 2025

Abstract

Described are polymerizable high energy light absorbing compounds. The compounds absorb various wavelengths of ultraviolet and/or high energy visible light and are suitable for incorporation in various products, such as biomedical devices and ophthalmic devices. Such devices exhibit a number of desirable properties, including favorable rates of pervaporation.

First claim

We claim:

1 . A contact lens that is a free radical reaction product of a reactive mixture comprising:
one or more monomers suitable for making the contact lens; a high energy visible (HEV) light absorbing compound; and a polyamide internal wetting agent in an amount of up to eleven weight percent,
wherein the contact lens transmits from 0 percent to 70 percent of light having a wavelength range of 400 to 409 nm, and wherein the contact lens exhibits a pervaporation rate of less than 0.47 uL/min*cm 2 when measured at a relative humidity of about 0 percent.

2 . The contact lens of claim 1 wherein the pervaporation rate is less than 0.45 uL/min*cm 2 .

3 . The contact lens of claim 1 wherein the pervaporation rate is less than 0.41 uL/min*cm 2 .

4 . The contact lens of claim 1 wherein the reactive mixture contains less than 9 weight percent of the polyamide internal wetting agent.

5 . The contact lens of claim 1 that transmits from 0.2 percent to 70 percent of light having a wavelength range of 400 to 409 nm.

6 . The contact lens of claim 1 that transmits from 1 percent to 70 percent of light having a wavelength range of 400 to 409 nm.

7 . The contact lens of claim 1 that transmits 45 percent or less of light having a wavelength range of 280 to 399 nm.

8 . The contact lens of claim 1 that transmits at least 80 percent of light having a wavelength range of 450 to 800 nm.

9 . The contact lens of claim 1 that transmits: 45 percent or less of light having a wavelength range of 280 to 399 nm; from 1 percent to 70 percent of light having a wavelength range of 400 to 409 nm; and at least 80 percent of light having a wavelength range of 450 to 800 nm.

10 . The contact lens of claim 9 that transmits: from 10 percent to 95 percent of light having a wavelength range of 410 to 424 nm; and at least 50 percent of light having a wavelength range of 425 to 449 nm.

11 . The contact lens of claim 10 that transmits: 20 percent or less of light having a wavelength range of 280 to 399 nm; from 3 percent to 70 percent of light having a wavelength range of 400 to 409 nm; and at least 85 percent of light having a wavelength range of 450 to 800 nm.

12 . The contact lens of claim 1 wherein the monomer suitable for making the ophthalmic device comprises a hydrophilic component, a silicone-containing component, or mixtures thereof.

13 . A silicone hydrogel contact lens that is a reaction product of a reactive mixture comprising: a polymerizable high energy light absorbing compound; one or more monomers suitable for making the silicone hydrogel contact lens; and a polyamide internal wetting agent in an amount of up to eleven weight percent, wherein the silicone hydrogel contact lens has a contact angle of about 70° or less, a water content of at least 25 percent, and an oxygen permeability of at least 80 barrers, wherein the silicone hydrogel contact lens is substantially photostable, and wherein the silicone hydrogel contact lens exhibits a pervaporation rate of less than 0.47 uL/min*cm 2 when measured at a relative humidity of about 0 percent.

14 . The silicone hydrogel contact lens of claim 13 wherein the pervaporation rate is less than about 0.45 uL/min*cm 2 .

15 . The silicone hydrogel contact lens of claim 13 wherein the pervaporation rate is less than 0.41 uL/min*cm 2 .

16 . The silicone hydrogel contact lens of claim 13 wherein the reactive mixture contains less than 9 weight percent of the polyamide internal wetting agent.

17 . The silicone hydrogel contact lens of claim 13 wherein the lens transmits: from 0 percent to 70 percent of light having a wavelength of 400 to 409 nm; and at least 80 percent of light having a wavelength of 450 to 800 nm.

18 . The silicone hydrogel contact lens of claim 13 wherein the lens transmits: from 0.2 percent to 70 percent of light having a wavelength of 400 to 409 nm; and at least 80 percent of light having a wavelength of 450 to 800 nm.

19 . The silicone hydrogel contact lens of claim 13 wherein the lens transmits: from 1 percent to 70 percent of light having a wavelength of 400 to 409 nm; and at least 80 percent of light having a wavelength of 450 to 800 nm.

20 . A method for improving a vision attribute in a contact lens wearer, the method comprising: providing the contact lens wearer with the contact lens of claim 1 or 13 , wherein the vision attribute is selected from one or more of photostress recovery time, glare discomfort, glare disability threshold, heterochromatic contrast threshold, halo size, starburst size, and light scattering.

Assignees

• Johnson & Johnson Vision Care

Inventors

• Riederer Donald E
• Martin Patricia
• Mahadevan Shivkumar
• Wright Dawn D
• Buch John R
• Cannon Jessica

Classifications

• C08F230/08

  containing silicon · CPC title

• A61L27/00

  Materials for {grafts or} prostheses or for coating {grafts or} prostheses (dental prostheses A61C13/00; shape or structure of prostheses A61F2/00; use of preparations for artificial teeth A61K6/80; artificial kidneys A61M1/14) · CPC title

• C08L77/00

  Compositions of polyamides obtained by reactions forming a carboxylic amide link in the main chain (of polyhydrazides C08L79/06; of polyamideimides or polyamide acids C08L79/08); Compositions of derivatives of such polymers · CPC title

• C08K5/45

  Heterocyclic compounds having sulfur in the ring · CPC title

• C08K5/1545

  Six-membered rings · CPC title