Guide wire

Patent metadata

Field	Value
Publication number	US-12485252-B2
Application number	US-202217835477-A
Country	US
Kind code	B2
Filing date	Jun 8, 2022
Priority date	Mar 30, 2020
Publication date	Dec 2, 2025
Grant date	Dec 2, 2025

Abstract

A guide wire with improved joining strength is provided. The guide wire includes a first wire and a second wire are solid-phase-joined to each other, the first wire and the second wire are made of a Ni—Ti-based alloy. When a section of a crystal grain size is 1 μm in a number-based particle size distribution of crystal grains of a metallographic structure of a joint surface between the first wire and the second wire, the frequency of the crystal grains having a mode particle size is 25% or more and the frequency of the crystal grains having a crystal grain size with a representative diameter of (mode particle size (μm)−1 μm) or more and (mode particle size (μm)+1 μm) or less is 60% or more.

First claim

What is claimed is:

1 . A guide wire comprising:
a first wire and a second wire that are solid-phase-joined to each other, the first wire and the second wire being made of a nickel-titanium-based alloy; in a section of a crystal grain size of 1 μm in a number-based particle size distribution of crystal grains of a metallographic structure of a joint surface between the first wire and the second wire, a frequency of a mode particle size is 25% or more and a frequency of a representative diameter being (mode particle size (μm)−1 μm) or more and (mode particle size (μm)+1 μm) or less is 60% or more; and wherein the section of the crystal grain size is a sectional width used in the number-based particle size distribution of crystal grains, the mode particle size is a representative diameter of a section with a highest frequency in the number-based particle size distribution, and the representative diameter is a median value of each section in the number-based particle size distribution.

2 . The guide wire according to claim 1 , wherein the mode particle size is 2.50 μm or more.

3 . The guide wire according to claim 1 , wherein a standard deviation of hardness at the joint surface is 10.00 or less measured in Vickers hardness and the standard deviation is calculated as an unbiased standard deviation based on five measurement points in accordance with ISO 14577-1.

4 . The guide wire according to claim 1 , wherein the joint surface includes a joint portion protruding radially outward from outer surfaces of the first wire and the second wire.

5 . The guide wire according to claim 1 , wherein the first wire includes a distal portion disposed on a distal side of the first wire, a first constant outer diameter portion disposed on a proximal side of the distal portion of the first wire, and a first tapered portion disposed between the distal portion of the first wire and the first constant outer portion of the first wire.

6 . The guide wire according to claim 5 , wherein the second wire includes a second constant outer diameter portion disposed on a distal side of the second wire, a third constant outer diameter portion disposed on a proximal side of the second constant outer diameter portion, and a second tapered portion disposed between the second constant outer diameter portion and the third constant outer diameter portion.

7 . The guide wire according to claim 1 , further comprising:
an outer diameter of the first wire being different than an outer diameter of the second wire.

8 . The guide wire according to claim 1 , wherein an outer diameter of the guide wire at a position at 150 mm from a joint surface between the first wire and the second wire to a proximal side of the guide wire is 115% or more than an outer diameter at a 150 mm from the joint surface to a distal side of the guide wire.

9 . The guide wire according to claim 1 , wherein the mode particle size is 2.5 μm to 5.5 μm.

10 . The guide wire according to claim 1 , wherein the mode particle size is 2.5 μm to 3.5 μm.

11 . A guide wire, the guide wire comprising:
a first wire; a second wire solid-phase joined to the first wire; in a section of a crystal grain size of 1 μm in a number-based particle size distribution of crystal grains of a metallographic structure of a joint surface between the first wire and the second wire, a frequency of a mode particle size is 25% or more and a frequency of a representative diameter being (mode particle size (μm)−1 μm) or more and (mode particle size (μm)+1 μm) or less is 60% or more; and wherein the section of the crystal grain size is a sectional width used in the number-based particle size distribution of crystal grains, the mode particle size is a representative diameter of a section with a highest frequency in the number-based particle size distribution, and the representative diameter is a median value of each section in the number-based particle size distribution.

12 . The guide wire according to claim 11 , wherein
the first wire and the second wire are made of a nickel-titanium-based alloy; and the mode particle size is 2.5 μm to 3.5 μm.

13 . The guide wire according to claim 11 , wherein
the first wire includes a distal portion disposed on a distal side of the first wire, a first constant outer diameter portion disposed on a proximal side of the distal portion of the first wire, and a first tapered portion disposed between the distal portion of the first wire and the first constant outer portion of the first wire; and the second wire includes a second constant outer diameter portion disposed on a distal side of the second wire, a third constant outer diameter portion disposed on a proximal side of the second constant outer diameter portion, and a second tapered portion disposed between the second constant outer diameter portion and the third constant outer diameter portion.

14 . The guide wire according to claim 11 , further comprising:
a coil arranged on a distal portion of the first wire, the coil including a spirally wound wire around the first wire along a circumferential direction of the first wire; a distal coating layer of a resin material on the distal portion of the first wire including the coil; and a tubular member arranged proximal to the distal coating layer of the first wire and to a distal side of the joint surface of the first wire and the second wire.

15 . The guide wire according to claim 14 , further comprising:
a proximal coating layer covering at least a part of an outer surface of the second wire.

16 . A method of forming a guide wire, the method comprising:
solid-phase joining a first wire and a second wire to each other such that in a section of a crystal grain size of 1 μm in a number-based particle size distribution of crystal grains of a metallographic structure of a joint surface between the first wire and the second wire, a frequency of a mode particle size is 25% or more and a frequency of a representative diameter being (mode particle size (μm)−1 μm) or more and (mode particle size (μm)+1 μm) or less is 60% or more, the section of the crystal grain size being a sectional width used in the number-based particle size distribution of crystal grains, the mode particle size being a representative diameter of a section with a highest frequency in the number-based particle size distribution, and the representative diameter being a median value of each section in the number-based particle size distribution.

17 . The method according to claim 16 , further comprising:
solid-phase joining the first wire and the second wire to each other by friction joining, room-temperature pressure joining, high-temperature pressure joining, explosive joining, or electromagnetic pulse joining.

18 . The method according to claim 16 , wherein the solid-phase joining of the first wire and the second wire to each other comprises:
bringing a surface of the first wire into pressure contact with a surface of the second wire in an axial direction; and inputting heat to the surfaces of the first wire and the second wire that are in contact with each other.

19 . The method according to claim 18 , further comprising:
compressing the first wire and the second wire in a longitudinal direction, and wherein the first wire and the second wire extrude radially outward as a result of the compression.

20 . The method according to claim 19 , further comprising:
mechanically polishing the first wire and the second wire where the first wire and the second wire extrude radial

Assignees

• Terumo Corp

Inventors

• Fukuda Takumi
• Sugiyama Fuminori

Classifications

• C22C19/03 Primary

  based on nickel · CPC title

• B23K20/22

  taking account of the properties of the materials to be welded · CPC title

• B23K20/004

  Wire welding · CPC title

• A61M2025/09133

  having specific material compositions or coatings; Materials with specific mechanical behaviours, e.g. stiffness, strength to transmit torque · CPC title

• A61M2025/09108

  Methods for making a guide wire · CPC title