Expanded foam for delivery of functional ingredients

Patent metadata

Field	Value
Publication number	US-12484600-B2
Application number	US-202117759132-A
Country	US
Kind code	B2
Filing date	Jan 19, 2021
Priority date	Jan 21, 2020
Publication date	Dec 2, 2025
Grant date	Dec 2, 2025

Abstract

The present disclosure provides delivery systems for functional ingredients, such as drugs, nutritional supplements, botanicals, and vitamins. The delivery systems comprise an ingestible matrix within which the functional ingredient(s) are substantially uniformly and completely dispersed. The matrix comprises foams derived by physical shear of egg white to achieve amplified available dose and improved release characteristics of functional ingredients at skin and mucosal surfaces for healthcare purposes. The disclosure also provides methods of preparing and using the delivery systems.

First claim

The invention claimed is:

1 . A delivery system for functional ingredients comprising one or more functional ingredient(s) substantially uniformly dispersed in a matrix, wherein said matrix comprises:
i) an egg white foam comprising between 1-50% protein; ii) one or more heat resistant and/or heat sensitive gelling agents; iii) a pH regulator; iv) one or more plasticizers and/or humectants; and v) one or more sources of water.

2 . The delivery system according to claim 1 , wherein said one or more gelling agents comprises agar.

3 . The delivery system according to claim 1 , wherein said one or more gelling agents comprises gelatin.

4 . The delivery system according to claim 1 , wherein said one or more gelling agents comprises pectin.

5 . The delivery system according to claim 1 , wherein said one or more gelling agents comprises at least two gelling agents selected from agar, gelatin, and pectin.

6 . The delivery system according to claim 1 , wherein said pH regulator is citric acid.

7 . The delivery system according to claim 1 , wherein said one or more functional ingredient(s) comprises a functional emulsion.

8 . The delivery system according to claim 1 , comprising two or more functional ingredient(s).

9 . The delivery system according to claim 7 , further comprising a chelating agent.

10 . The delivery system according to claim 9 , wherein the chelating agent is a polyphosphate.

11 . The delivery system according to claim 10 , wherein the polyphosphate is sodium hexametaphosphate.

12 . The delivery system according to claim 1 , wherein said one or more functional ingredients are selected from the group of drugs, botanicals, nutritional supplements, vitamins, minerals, enzymes, hormones, proteins, polypeptides and antigens.

13 . The delivery system according to claim 1 , further comprising a sweetener, a buffer, a natural or artificial flavoring, a coloring agent, or a combination thereof.

14 . A dual action dental chew for dogs, wherein the dental chew comprises two components; a flexible base and a filling, and wherein the filling comprises the delivery system according to claim 1 .

15 . The dual action dental chew for dogs according to claim 14 , wherein the flexible base is shaped and designed to reduce plaque and calculus through mechanical action during the chewing process, and wherein the flexible base features a reservoir or cavity for the filling.

16 . The dual action dental chew for dogs according to claim 14 , wherein the mechanical action is scrubbing and/or abrasion.

17 . The dual action dental chew for dogs according to claim 14 , wherein the delivery system comprises a functional ingredient comprising an emulsion comprising (a) one or more saturated or unsaturated free fatty acids having from 4 to 22 carbon atoms or a pharmaceutically acceptable salt thereof; and (b) one or more delipidised membrane lipids, as emulsifying agent for the free fatty acid(s) or the salt thereof.

18 . A method of using the delivery system according to claim 1 for oral administration of one or more functional ingredient to an animal in need thereof comprising administering the delivery system to the animal in need.

Assignees

• Boehringer Ingelheim Vetmedica Gmbh
• Westgate Biomedical Ltd

Inventors

• Folan Michael A
• Folan David J

Classifications

• A23K50/42

  Dry feed · CPC title

• A23L29/231

  Pectin; Derivatives thereof · CPC title

• A23L29/284

  Gelatin; Collagen · CPC title

• A23L29/256

  from seaweeds, e.g. alginates, agar or carrageenan · CPC title

• A23P10/00

  Shaping or working of foodstuffs characterised by the products · CPC title