Centrifugal field-flow fractionation device

Patent metadata

Field	Value
Publication number	US-12478983-B2
Application number	US-202017791822-A
Country	US
Kind code	B2
Filing date	Dec 24, 2020
Priority date	Jan 9, 2020
Publication date	Nov 25, 2025
Grant date	Nov 25, 2025

Abstract

A centrifugal field-flow fractionation device includes: a rotor having a rotation axis, the rotor being provided to be rotatable about the rotation axis; a cover covering the rotor; a protective member arranged inside the cover to over the rotor about the rotation axis; a shock-absorbing member arranged between the protective member and the cover; and a fixing part provided in a breakable manner to fix the protective member to the cover. The rotor is arranged such that the rotation axis orients in a horizontal direction. In a case where a part of the rotor disintegrates and is brought into contact with the protective member during the rotation of the rotor, the fixing part breaks to cause the protective member and the shock-absorbing member to move with the rotor while receiving the impact of the rotor to buffer the kinetic energy of the rotor.

First claim

The invention claimed is:

1 . A centrifugal field-flow fractionation device comprising:
a rotor having a rotation axis, the rotor being provided to be rotatable about the rotation axis; a cover configured to cover the rotor; a protective member arranged on an inner side of the cover, the protective member covering the rotor about the rotation axis; a shock-absorbing member arranged between the protective member and the cover; and a fixing part provided in a breakable manner, the fixing part fixing the protective member to the cover, wherein the rotor is arranged such that the rotation axis orients in a horizontal direction, and wherein in a case where a portion of the rotor disintegrates and is brought into contact with the protective member during a rotation of the rotor, the fixing part breaks to allow the protective member and the shock-absorbing member to be movable together with the rotor while receiving impact of the rotor to buffer kinetic energy of the rotor.

2 . The centrifugal field-flow fractionation device as recited in claim 1 ,
wherein the cover includes an installation portion for installing an outer peripheral portion of the shock-absorbing member, wherein the installation portion has a first end in a direction parallel to the rotation axis, wherein the protective member has a second end on a side where the first end is located in the direction parallel to the rotation axis, and wherein the fixing part includes one or more connection members connecting the first end and the second end.

3 . The centrifugal field-flow fractionation device as recited in claim 1 ,
wherein the fixing part is provided to connect an inner surface of the cover and the protective member.

4 . The centrifugal field-flow fractionation device as recited in claim 1 , further comprising:
a flow path member provided along an inner peripheral surface of the rotor, the flow path member being configured to allow a liquid sample to flow therethrough; and a leaked liquid recovery tray configured to recover the liquid sample leaking from the flow path member, wherein the leaked liquid recovery tray is arranged between the protective member and the rotor, the leaked liquid recovery tray having a peripheral wall covering the rotor about the rotation axis.

5 . The centrifugal field-flow fractionation device as cited in claim 4 , further comprising:
a tray fixing part configured to fix the leaked liquid recovery tray to the cover, wherein the tray fixing part is provided so as to be broken in a case where a part of the rotor disintegrates and is brought into contact with the leaked liquid recovery tray during the rotation of the rotor.

6 . The centrifugal field-flow fractionation device as recited in claim 4 ,
wherein piping configured to discharge the recovered leaked liquid is connected to a lower part of the leaked liquid recovery tray, and wherein on a lower part side of the leaked liquid recovery tray, an inner peripheral surface of the peripheral wall of the leaked liquid recovery tray has an inclined portion inclined toward the piping.

7 . The centrifugal field-flow fractionation device as recited in claim 4 ,
wherein the leaked liquid recovery tray is integrally provided with the protective member.

Assignees

• Shimadzu Corp

Inventors

• Aoki Kengo

Classifications

• G01N2015/0288

  Sorting the particles · CPC title

• G01N2015/0053

  in liquids, e.g. trouble · CPC title

• G01N15/0255

  with mechanical, e.g. inertial, classification, and investigation of sorted collections (with centrifuges G01N15/042) · CPC title

• B04B2007/065

  Devices and measures in the event of rotor fracturing, e.g. lines of weakness, stress regions · CPC title

• B04B15/00

  Other accessories for centrifuges · CPC title