Pipette tip carrier assembly

Patent metadata

Field	Value
Publication number	US-12478973-B2
Application number	US-202017602897-A
Country	US
Kind code	B2
Filing date	Apr 8, 2020
Priority date	Apr 12, 2019
Publication date	Nov 25, 2025
Grant date	Nov 25, 2025

Abstract

A pipette tip carrier assembly suitable for storing elongate pipette tips in a biochemical analyser is described. The pipette tip carrier assembly comprises one or more holding elements each adapted to hold, in use, a respective pipette tip oriented such that the elongate dimension of the held pipette tip is parallel to a first axis. The pipette tip carrier assembly also includes a light source arranged to produce, at a position distal to the one or more holding elements along the first axis, light directed towards each of the one or more holding elements so as to be intercepted by one or more pipette tips held in 10 use by the one or more holding elements.

First claim

The invention claimed is:

1 . A pipette tip carrier assembly for storing one or more pipette tips in a biochemical analyser, each pipette tip of the one or more pipette tips having an elongate dimension, the pipette tip carrier assembly comprising:
a frame; a container; and a locking mechanism; wherein
the frame comprises an array of holding elements, each holding element of the array of holding elements configured to hold, in use, a respective pipette tip such that the elongate dimension of each respective pipette tip is held parallel to a first axis
the container comprises an opening configured to hold, in use, the frame such that each pipette tip held by the array of holding elements extends through the frame and into the container;
the container and the frame cooperatively define a restraining structure comprising a flange on the container, the flange configured to allow the frame to move in a direction perpendicular to the first axis when the frame is held at the opening of the container, the restraining structure configured to prevent the frame from moving along the first axis when the frame is held at the opening of the container whereby the frame is prevented from detaching from the pipette tip carrier assembly; and
the locking mechanism is configured to urge the frame, in an engaged state, into a place wherein the frame is fixed, in relation to the container, under the flange and to prevent the frame, in the engaged state, from moving perpendicular to the first axis.

2 . The pipette tip carrier assembly of claim 1 , wherein the locking mechanism comprises a rotatable cam adjacent to the opening of the container; is configured to rotate between an engaged position and a disengaged position; and is configured to urge the frame into the restraining structure when rotated into the engaged position.

3 . The pipette tip carrier assembly of claim 2 , wherein the rotatable cam is configured to enable the frame to release from the restraining structure when the rotatable cam is rotated into the disengaged position.

4 . The pipette tip carrier assembly of claim 1 , wherein the container or the frame or both comprises one or more reference holes and the locking mechanism comprises one or more protrusions configured to cover the one or more reference holes in the container or in the frame or in both when the locking mechanism is in the engaged state, and to not cover the one or more reference holes when in a disengaged state; or to cover the one or more reference holes when the locking mechanism is in the disengaged state, and to not cover the one or more references holes when in the engaged state.

5 . The pipette tip carrier assembly of claim 1 , wherein the container or the frame or both comprises one or more reference holes and the pipette tip carrier assembly further comprising a light source arranged from within the container and to direct light towards the array of holding elements and the one or more reference holes.

6 . A pipette tip storage system comprising:
a detector; and a pipette tip container assembly for storing one or more pipette tips in a biochemical analyser, each pipette tip of the one or more pipette tips having an elongate dimension, the pipette tip container assembly comprising:
a light source;
a frame;
a container; and
a locking mechanism, wherein:
the frame comprises an array of holding elements, each holding element of the array of holding elements configured to hold, in use, a respective pipette tip such that the elongate dimension of each respective pipette tip is held parallel to a first axis;
the container comprises an opening configured to hold, in use, the frame such that each pipette tip held by the array of holding elements extends through the frame and into the container;
the container and the frame cooperatively define a restraining structure comprising a flange on the container, the flange configured to allow the frame to move in a direction perpendicular to the first axis when the frame is held at the opening of the container, the restraining structure configured to prevent the frame from moving along the first axis when the frame is held at the opening of the container whereby the frame is prevented from detaching from the pipette tip container assembly;
the locking mechanism is configured to urge the frame, in an engaged state, into a place wherein the frame is fixed, in relation to the container, under the flange and prevent the frame, in the engaged state, from moving perpendicular to the first axis;
the light source is arranged to direct light towards the array of holding elements;
the container or the frame or both comprises one or more reference holes; and wherein:

the detector is arranged external to the container and is configured to detect light from the light source exiting the container via the array of holding elements and the one or more reference holes.

Assignees

• Randox Laboratories Ltd

Inventors

• Mcgleenan Proinnsias
• Evans P
• Jackson Stuart
• Reid Martin
• Fitzgerald Peter

Classifications

• B01L2300/0809

  rectangular shaped · CPC title

• B01L2200/04

  Exchange or ejection of cartridges, containers or reservoirs · CPC title

• B01L2200/025

  Align devices or objects to ensure defined positions relative to each other · CPC title

• G01N2035/103

  using disposable tips · CPC title

• B01L2300/168

  Specific optical properties, e.g. reflective coatings · CPC title