Coating composition free of titanium dioxide

Patent metadata

Field	Value
Publication number	US-12466972-B2
Application number	US-201816626764-A
Country	US
Kind code	B2
Filing date	Jul 12, 2018
Priority date	Jul 27, 2017
Publication date	Nov 11, 2025
Grant date	Nov 11, 2025

Abstract

Disclosed is a coating composition including, in relation to 100% of the weight thereof: 10-90 wt. % of at least one film-forming polymer selected from methyl cellulose, hydroxy propyl methyl cellulose, hydroxy propyl cellulose, hydroxy ethyl cellulose, sodium carboxy methyl cellulose, ethyl cellulose, PVA (polyvinyl alcohols), PVA-PEG (polyethylene glycol) copolymers, polyvinyl acetate, polyvinyl pyrrolidones (PVP), vinylpyrrolidone-vinyl acetate copolymers, alginates, pectin, arabic gum, guar gum, carrageenans, xanthan gum, inulin, chitosan, methacrylic acid copolymer, ethyl acetate, or polyethylene glycol-polypropylene glycol (PEG-PPG) copolymer; 0-50 wt. % of at least one auxiliary coating agent selected from diluents, surfactants, plasticisers and anti-foaming agents; and 10-50 wt. % of a whitening filler free of titanium dioxide including at least one alkaline or alkaline earth salt of a fatty acid and at least one cellulose compound selected from cellulose, cellulose powder, microcrystalline cellulose, or a mixture of the components.

First claim

The invention claimed is:

1 . A coating composition comprising, per 100% of its weight:
from 40% to 60% by weight of a film-forming polymer, said film-forming polymer being hydroxypropyl methylcellulose (HPMC), from 0% to 20% by weight of at least one auxiliary coating agent chosen from diluents, surfactants, plasticizers or antifoaming agents, and from 20% to 40% by weight of a whitening filler devoid of titanium dioxide comprising at least one alkali metal or alkaline earth metal fatty acid salt chosen from the magnesium salt of stearic acid and the calcium salt of stearic acid and at least one cellulose compound chosen from cellulose, cellulose powder, microcrystalline cellulose or a mixture of these components; wherein at least 90% by volume of the particles of said at least one cellulose compound have a diameter of 40 to 60 micrometers; wherein said HPMC is present in a greater amount by weight than said whitening filler devoid of titanium dioxide; wherein the whitening filler is composed, per 100% of weight, of 25% to 75% by weight of said alkali metal or alkaline earth metal fatty acid salt and of 25% to 75% by weight of said cellulose compound; and wherein said coating composition is in the form of mixtures of powders or of granules.

2 . The coating composition as claimed in claim 1 , wherein said at least one auxiliary coating agent is chosen from diluents; or antifoaming agents.

3 . The coating composition as claimed in claim 1 , wherein the alkali metal or alkaline earth metal fatty acid salt is magnesium stearate.

4 . A process for the preparation of the coating composition as defined in claim 1 and which is provided in the form of a dry powder, comprising the following stages:
a stage (a) of mixing the film-forming polymer, the whitening filler and, if necessary or if desired, one or more other coating auxiliaries,
a stage (b) of grinding the mixture resulting from stage (a), in order to form said coating composition.

5 . A process for the preparation of a coating composition as defined in claim 1 and which is provided in the form of ready-for-use granules, comprising the following stages:
a stage (a1) of wetting the mixture of film-forming polymer, of the whitening filler and, if necessary or if desired, of one or more other coating auxiliaries with a binding solution, in order to obtain a wet mass containing from 30% to 60% of water,
a stage (b1) of drying the wet mass obtained in stage (a1) and, if desired or if necessary,
a stage (c1) of grading the dried mass obtained in stage (b1), in order to obtain said coating composition.

6 . A process for the preparation of the coating composition as defined in claim 1 and which is provided in the form of an aqueous dispersion, comprising the following stages:
a stage (a2) of dispersing the film-forming polymer, the whitening filler and, if necessary or if desired, one or more other coating auxiliaries in an aqueous phase,
a stage (b2) of grinding the mixture resulting from stage (a1), in order to form said coating composition.

7 . An ingestible solid form having a coating comprising the coating composition as defined in claim 1 .

8 . The coating composition as defined in claim 1 , wherein a weight ratio of HPMC to the whitening filler devoid of titanium dioxide is 3:2.

9 . A coating composition comprising, per 100% of its weight:
from 40% to 60% by weight of a film-forming polymer, said film-forming polymer being hydroxypropyl methylcellulose (HPMC), from 0% to 20% by weight of at least one auxiliary coating agent chosen from diluents, surfactants, plasticizers or antifoaming agents, and from 20% to 40% by weight of a whitening filler devoid of titanium dioxide comprising at least one alkali metal or alkaline earth metal fatty acid salt chosen from the magnesium salt of stearic acid and the calcium salt of stearic acid and at least one cellulose compound chosen from cellulose, cellulose powder, microcrystalline cellulose or a mixture of these components; wherein said HPMC is present in a greater amount by weight than said whitening filler devoid of titanium dioxide; wherein the whitening filler is composed, per 100% of weight, of 25% to 75% by weight of said alkali metal or alkaline earth metal fatty acid salt and of 25% to 75% by weight of said cellulose compound; wherein said coating composition is in the form of mixtures of powders or of granules; and wherein said composition, when dispersed in water and sprayed on previously uncoated tablets, yields measured L* values of the CIELAB color space of 96 or 97.

10 . The coating composition as claimed in claim 9 , wherein said at least one auxiliary coating agent is chosen from diluents; or antifoaming agents.

11 . The coating composition as claimed in claim 9 , wherein the alkali metal or alkaline earth metal fatty acid salt is magnesium stearate.

12 . The coating composition as defined in claim 9 , wherein a weight ratio of HPMC to the whitening filler devoid of titanium dioxide is 3:2.

Assignees

• Soc Dexploitation De Produits Pour Les Industries Chimiques Seppic

Inventors

• Despax Stéphanie
• Faget Sophie

Classifications

• C09D101/08

  Cellulose derivatives · CPC title

• C09D5/033

  characterised by the additives · CPC title

• C09D5/024

  characterised by the additives · CPC title

• C08K2201/019

  the composition being defined by the absence of a certain additive · CPC title

• C08K2201/003

  Additives being defined by their diameter · CPC title