Sync pulse detector

Patent metadata

Field	Value
Publication number	US-12458803-B2
Application number	US-202217670025-A
Country	US
Kind code	B2
Filing date	Feb 11, 2022
Priority date	Aug 18, 2015
Publication date	Nov 4, 2025
Grant date	Nov 4, 2025

Abstract

Disclosed herein are devices and methods used with neurostimulation therapy for spinal cord injury. More particularly, embodiments of the present invention relate to a sync pulse detector and methods for synchronizing signals from an implanted neurostimulator with measured physiological responses and other data.

First claim

What is claimed is:

1 . A sync pulse detector system for a patient, the sync pulse detector system comprising:
a neurostimulator including an implantable electrode array, the neurostimulator being configured to
provide a variety of electrical stimulations to the patient via the implantable electrode array,
wirelessly transmit a plurality of non-packet based electromagnetic synchronization pulses such that each of the non-packet based electromagnetic synchronization pulses signifies a respective initiation of a respective one of the electrical stimulations, and
not deliver the non-packet based electromagnetic synchronization pulses to the patient via the electrode array; and
a sync pulse detector including
a housing,
a receiver being configured to receive the non-packet based electromagnetic synchronization pulses,
a circuit within the housing and operably coupled to the receiver, the circuit being configured to convert the non-packet based electromagnetic synchronization pulses into respective digital signals, and
a means, operably coupled to the circuit, for transmitting the digital signals from the sync pulse detector,
wherein the sync pulse detector is configured to reside outside of the patient; and
a receiving device operably coupled to the circuit and operably coupled to the neurostimulator, the receiving device being configured to
receive the digital signals,
receive physiological data corresponding to physiological responses of the patient to the electrical stimulations, and
cause, based on the digital signals and the physiological data, a synchronization of the electrical stimulations to the physiological responses of the patient.

2 . The sync pulse detector system of claim 1 , wherein the receiver is an inductive coil.

3 . The sync pulse detector system of claim 2 , wherein the inductive coil is inductively coupled to the neurostimulator.

4 . The sync pulse detector system of claim 1 , wherein the digital signals are square waves.

5 . The sync pulse detector system of claim 3 , wherein the neurostimulator is entirely implantable.

6 . The sync pulse detector system of claim 5 , wherein the neurostimulator is configured to provide epidural stimulation to the patient via the electrode array.

7 . The sync pulse detector system of claim 1 , wherein the sync pulse detector is configured to transmit each of the digital signals from the sync pulse detector within approximately one millisecond of receiving a respective one of the non-packet based electromagnetic synchronization pulses.

8 . The sync pulse detector system of claim 7 , wherein the neurostimulator is entirely implantable.

9 . The sync pulse detector system of claim 8 , wherein the neurostimulator is configured to provide epidural stimulation to the patient via the electrode array.

10 . The sync pulse detector system of claim 9 , wherein the receiver is configured to cause the synchronization based on electromyogram data.

11 . The sync pulse detector system of claim 9 , wherein the receiver is configured to cause the synchronization based on blood pressure data.

Assignees

• Univ Louisville Res Found Inc

Inventors

• Harkema Susan J
• Chen Yangsheng
• Jackson Douglas J
• Ravi Manikandan
• Angeli Claudia

Classifications

• A61N1/378

  Electrical supply · CPC title

• A61N1/37282

  characterised by communication with experts in remote locations using a network · CPC title

• A61N1/37223

  Circuits for electromagnetic coupling · CPC title

• A61B5/0031

  Implanted circuitry · CPC title

• A61B5/395

  Details of stimulation, e.g. nerve stimulation to elicit EMG response · CPC title