Method of measuring speed of blood flow from RF signal

Patent metadata

Field	Value
Publication number	US-12446848-B2
Application number	US-202218710810-A
Country	US
Kind code	B2
Filing date	Nov 21, 2022
Priority date	Dec 24, 2021
Publication date	Oct 21, 2025
Grant date	Oct 21, 2025

Abstract

A method of measuring a speed of blood flow from a radio frequency (RF) signal, including decomposing a complex signal converted from the RF signal into base signals using singular value decomposition, classifying the base signals into a clutter signal, a blood flow signal, and a noise signal, separating a clutter region and a blood flow region from the classified clutter signal and blood flow signal, obtaining an output signal by removing the blood flow signal from the clutter signal in the clutter region and by removing the clutter signal from the blood flow signal in the blood flow region, and measuring a speed of the blood flow by calculating speckle decorrelation from the output signal.

First claim

The invention claimed is:

1. A method of measuring a speed of blood flow from a radio frequency (RF) signal, the method comprising:
decomposing a complex signal converted from the RF signal into base signals using singular value decomposition;
classifying the base signals into a clutter signal, a blood flow signal, and a noise signal;
separating a clutter region and a blood flow region from the classified clutter signal and blood flow signal, wherein the separating comprises
obtaining a feature map on a basis of at least one selected from the group consisting of a) the blood flow signal and b) the clutter signal and the blood flow signal, wherein the feature map is obtained by converting an energy map showing energy of the blood flow signal into a decibel scale, and
obtaining the clutter region and the blood flow region by performing image separation on the feature map;

obtaining an output signal by removing the blood flow signal from the clutter signal in the clutter region and by removing the clutter signal from the blood flow signal in the blood flow region; and
measuring a speed of the blood flow by calculating speckle decorrelation from the output signal.

2. The method of claim 1 , wherein the base signals are expressed as a sum of a plurality of individual base signals,
the individual base signals each include a space singular vector, a time singular vector, and a singular value, and
the blood flow signal, the clutter signal, and the noise signal are classified on a basis of the singular value in the classifying.

3. The method of claim 2 , wherein, in the classifying, the blood flow signal and the clutter signal are classified on a basis of a magnitude of the singular value.

4. The method of claim 1 , further comprising smoothing the feature map after obtaining the feature map,
wherein the image separation is performed on the smoothed feature map.

5. The method of claim 1 , wherein the measuring of a speed of the blood flow comprises:
extracting a sign of the output signal;
obtaining a correlation value by inputting the extracted sign into a 1-bit correlator;
obtaining a corrected correlation value by correcting the correlation value; and
converting the corrected correlation value into a speed of blood flow using speckle calibration,
wherein the speckle calibration is obtained from data by measuring speckle decorrelation and a speckle movement distance.

Assignees

• Nat Cancer Ct

Inventors

• Park Dae Woo
• Park Dong Chan

Classifications

• A61B8/52

  Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves · CPC title

• A61B8/48

  Diagnostic techniques (A61B8/13 takes precedence) · CPC title

• A61B5/02021 Primary

  Determining capillary fragility · CPC title

• A61B5/05

  Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves (measuring movement of the entire body or parts thereof A61B5/11; detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof A61B5/24) · CPC title

• A61B8/5269

  involving detection or reduction of artifacts · CPC title