Method of treating cancer

US12440505B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-12440505-B2
Application numberUS-202117465921-A
CountryUS
Kind codeB2
Filing dateSep 3, 2021
Priority dateMar 5, 2019
Publication dateOct 14, 2025
Grant dateOct 14, 2025

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

There is provided with a method of treating cancer. A set of administration of a compound represented by General Formula (I) or a pharmaceutically acceptable salt thereof to a patient, at a dose such that 8 mg/kg or less of the compound represented by General Formula (I) is administered, and irradiation to the patient immediately following the administration is repeated. A total dosage of the irradiation to a cancer is 10 Gy or more.

First claim

Opening claim text (preview).

What is claimed is: 1. A method of treating cancer comprising repeating a set of administration of a compound represented by General Formula (I) or a pharmaceutically acceptable salt thereof to a patient, at a dosage such that 8 mg/kg or less of the compound represented by General Formula (I) is administered per dose, and irradiation to the patient immediately following the administration: where R 1 is an acyl residue from fatty acid, wherein a total dosage of the irradiation on a cancer is 10 Gy or more, and wherein the patient is a dog or cat. 2. The method according to claim 1 , comprising repeating the set at a frequency of once or less a day and once or more a month. 3. The method according to claim 1 , wherein the cancer is melanoma or lymphoma. 4. The method according to claim 1 , wherein the cancer is adenocarcinoma or squamous cell carcinoma. 5. The method according to claim 1 , wherein the dosage is such that the 0.5 mg/kg or more of the compound represented by General Formula (I) is administered per dose. 6. The method according to claim 1 , wherein R 1 is a stearoyl group. 7. The method according to claim 1 , wherein repeating the set of the administration and the irradiation leads to reduce the size of the cancer or eliminate the cancer. 8. The method according to claim 1 , wherein the total dosage of the irradiation on the cancer is 15 Gy or more. 9. The method according to claim 1 , wherein the set of the administration and the irradiation is repeated once or more every 2 weeks and repeated 10 times or less.

Assignees

Inventors

Classifications

  • Enhancing the effect of the particle by an injected agent or implanted device · CPC title

  • X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy (A61N5/01 takes precedence) · CPC title

  • Antineoplastic agents · CPC title

  • attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyldiacylglycerides, lactobionic acid, gangliosides · CPC title

  • Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages · CPC title

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What does patent US12440505B2 cover?
There is provided with a method of treating cancer. A set of administration of a compound represented by General Formula (I) or a pharmaceutically acceptable salt thereof to a patient, at a dose such that 8 mg/kg or less of the compound represented by General Formula (I) is administered, and irradiation to the patient immediately following the administration is repeated. A total dosage of the i…
Who is the assignee on this patent?
M T 3 Inc, Univ Nihon, School Corporation Azabu Veterinary Medicine Educational Inst
What technology area does this patent fall under?
Primary CPC classification A61K31/7032. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Oct 14 2025 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).