Personal Care Formulations
US-2024245591-A1 · Jul 25, 2024 · US
US12440505B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12440505-B2 |
| Application number | US-202117465921-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 3, 2021 |
| Priority date | Mar 5, 2019 |
| Publication date | Oct 14, 2025 |
| Grant date | Oct 14, 2025 |
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There is provided with a method of treating cancer. A set of administration of a compound represented by General Formula (I) or a pharmaceutically acceptable salt thereof to a patient, at a dose such that 8 mg/kg or less of the compound represented by General Formula (I) is administered, and irradiation to the patient immediately following the administration is repeated. A total dosage of the irradiation to a cancer is 10 Gy or more.
Opening claim text (preview).
What is claimed is: 1. A method of treating cancer comprising repeating a set of administration of a compound represented by General Formula (I) or a pharmaceutically acceptable salt thereof to a patient, at a dosage such that 8 mg/kg or less of the compound represented by General Formula (I) is administered per dose, and irradiation to the patient immediately following the administration: where R 1 is an acyl residue from fatty acid, wherein a total dosage of the irradiation on a cancer is 10 Gy or more, and wherein the patient is a dog or cat. 2. The method according to claim 1 , comprising repeating the set at a frequency of once or less a day and once or more a month. 3. The method according to claim 1 , wherein the cancer is melanoma or lymphoma. 4. The method according to claim 1 , wherein the cancer is adenocarcinoma or squamous cell carcinoma. 5. The method according to claim 1 , wherein the dosage is such that the 0.5 mg/kg or more of the compound represented by General Formula (I) is administered per dose. 6. The method according to claim 1 , wherein R 1 is a stearoyl group. 7. The method according to claim 1 , wherein repeating the set of the administration and the irradiation leads to reduce the size of the cancer or eliminate the cancer. 8. The method according to claim 1 , wherein the total dosage of the irradiation on the cancer is 15 Gy or more. 9. The method according to claim 1 , wherein the set of the administration and the irradiation is repeated once or more every 2 weeks and repeated 10 times or less.
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