Kras g12c inhibitors and methods of using the same
US-2019374542-A1 · Dec 12, 2019 · US
KRAS G12C inhibitors and methods of using the same
US12440491B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12440491-B2 |
| Application number | US-202318213464-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 23, 2023 |
| Priority date | May 4, 2018 |
| Publication date | Oct 14, 2025 |
| Grant date | Oct 14, 2025 |
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- Title
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- Abstract
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- Assignees and inventors
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Abstract
Official abstract text for this publication.
Provided herein are KRAS G12C inhibitors, composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.
First claim
Opening claim text (preview).
What is claimed: 1. A method of treating cancer in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a compound, wherein the compound is
Assignees
Inventors
- Allen John Gordon
- Allen Jennifer Rebecca
- Minatti Ana Elena
- Xue Qiufen
- Wurz Ryan Paul
- Tegley Christopher M
- Pickrell Alexander J
- Nguyen Thomas T
- Ma Vu Van
- Lopez Patricia
- Liu Longbin
- Kopecky David John
- Frohn Michael J
- Chen Ning
- Chen Jian Jeffrey
- Siegmund Aaron C
- Amegadzie Albert
- Tamayo Nuria A
- Booker Shon
- Goodman Clifford
- Walton Mary
- Nishimura Nobuko
- Shin Youngsook
- Low Jonathan D
- Cee Victor J
- Reed Anthony B
- Wang Hui-Ling
- Lanman Brian Alan
Classifications
- C07D471/04Primary
Ortho-condensed systems · CPC title
directly linked by a ring-member-to-ring-member bond · CPC title
against tumor tissues, cells, antigens · CPC title
Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems · CPC title
Antineoplastic agents · CPC title
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Frequently asked questions
Answers are generated from the same data shown on this page.
- What does patent US12440491B2 cover?
- Provided herein are KRAS G12C inhibitors, composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.
- Who is the assignee on this patent?
- Amgen Inc
- What technology area does this patent fall under?
- Primary CPC classification C07D471/04. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Oct 14 2025 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 12 related publications on this page (citations in our corpus or others sharing the same primary CPC).