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US-2015344544-A1 · Dec 3, 2015 · US
Nanobody targeting influenza a virus nucleoprotein and application thereof, and nucleic acid encoding nanobody
US12435126B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12435126-B2 |
| Application number | US-202418965925-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 2, 2024 |
| Priority date | Dec 14, 2023 |
| Publication date | Oct 7, 2025 |
| Grant date | Oct 7, 2025 |
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- Title
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Abstract
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Disclosed are a nanobody targeting influenza A virus nucleoprotein and an application thereof, and a nucleic acid encoding the nanobody. The present disclosure obtains one nanobody targeting influenza A virus nucleoprotein through construction of a nanobody phage library and phage screening technology. The nanobody targeting influenza A virus nucleoprotein is a VHH antibody fragment having an amino acid sequence shown in SEQ ID NO:1-SEQ ID NO:2. The nanobody in the present disclosure can specifically bind to influenza A virus nucleoprotein, and can be applied to the detection and analysis of influenza A virus, and has broad application prospects in the fields of early warning of the epidemic or outbreak of influenza A virus, as well as the detection of influenza A virus in the environment or human body.
First claim
Opening claim text (preview).
What is claimed is: 1. A nanobody targeting influenza A virus nucleoprotein, wherein the nanobody is a VHH antibody, and the nanobody has an amino acid sequence shown in SEQ ID NO:1 or SEQ ID NO:2. 2. A nucleic acid encoding the nanobody targeting influenza A virus nucleoprotein according to claim 1 , wherein a nucleotide sequence of the nucleic acid is shown in SEQ ID NO:3 or SEQ ID NO:4. 3. An application of the nanobody targeting influenza A virus nucleoprotein according to claim 1 , wherein the nanobody is applied in preparation of an influenza A virus detection kit.
Assignees
Inventors
Classifications
- C07K16/108Primary
Orthomyxoviridae (F), e.g. influenza virus · CPC title
Orthomyxoviridae, e.g. influenza virus · CPC title
- G01N33/56983Primary
Viruses · CPC title
Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody® · CPC title
from camelids, e.g. camel, llama or dromedary · CPC title
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- What does patent US12435126B2 cover?
- Disclosed are a nanobody targeting influenza A virus nucleoprotein and an application thereof, and a nucleic acid encoding the nanobody. The present disclosure obtains one nanobody targeting influenza A virus nucleoprotein through construction of a nanobody phage library and phage screening technology. The nanobody targeting influenza A virus nucleoprotein is a VHH antibody fragment having an a…
- Who is the assignee on this patent?
- Nanjing University
- What technology area does this patent fall under?
- Primary CPC classification C07K16/108. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Oct 07 2025 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).