Methods and systems for managing fluid flow in containers

Patent metadata

Field	Value
Publication number	US-12434172-B2
Application number	US-202118044179-A
Country	US
Kind code	B2
Filing date	Sep 22, 2021
Priority date	Sep 22, 2020
Publication date	Oct 7, 2025
Grant date	Oct 7, 2025

Abstract

Systems and methods for managing fluid flow in and evaporating solvents from containers are provided. In various embodiments, systems of the present disclosure provide for cap or cover members operable to be provided with vials or containers comprising one or more fluids. The caps are further operable to direct air and gas flow into and out of the containers. In some embodiments, supporting structures and heating elements are provided to enhance and assist various processes.

First claim

What is claimed is:

1. An apparatus operable for use in evaporating solvent from a container, the apparatus comprising:
a closure member comprising an upper portion and an extension;
the upper portion comprising an inlet provided at an angle relative to a longitudinal axis of the closure member;
the extension operable to extend into an internal volume of a container, and wherein the extension comprises a gas port for ejecting fluid provided to the inlet into the container;
an internal helical conduit extending within the extension that is operable to convey gas between the inlet and the gas port;
an exit channel extending through the closure member; and
wherein closure member comprises an annular sealing element.

2. The apparatus of claim 1 , further comprising a gas delivery line connected to the inlet.

3. The apparatus of claim 1 , wherein the exit channel comprises an exit port on the upper portion of the closure member.

4. The apparatus of claim 3 , wherein the exit channel comprises a threaded connection.

5. The apparatus of claim 1 , further comprising a vacuum line in fluid communication with the exit channel.

6. The apparatus of claim 1 , wherein the angle comprises an angle between 10 and 80 degrees.

7. The apparatus of claim 1 , wherein the apparatus comprises first, second, and third helical conduits.

8. A system operable for use in evaporating solvent from a container, the system comprising:
a plurality of cover members each comprising a gas inlet and a gas outlet;
an extension operable to extend into an internal volume of a container, and wherein the extension comprises a gas port for ejecting fluid provided to the inlet;
the gas outlet comprising an exit channel extending through each of the plurality of cover members;
an annular sealing element;
wherein each of the plurality of cover members are provided within a body member, and wherein the body member is secured to and adjustable relative to a support member; and
wherein each of the plurality of cover members comprise at least one biasing member in force transmitting communication with the body member, wherein the biasing member is operable to bias a first portion of each of the plurality of cover members relative to a second portion of each of the plurality of cover members and thereby facilitate a seal between the cover members and a respective container.

9. The system of claim 8 , wherein the gas inlet is in fluid communication with a helical conduit extending internally within the cover member.

10. The system of claim 8 , further comprising a gas delivery line connected to at least one of the gas inlets.

11. The apparatus of claim 8 , wherein the exit channel comprises an exit port.

12. The apparatus of claim 11 , wherein the exit port comprises a threaded connection.

13. The apparatus of claim 8 , further comprising a vacuum line in fluid communication with the exit channel.

14. The apparatus of claim 8 , wherein the gas inlet is provided at an angle that comprises an angle between 10 and 80 degrees.

15. The system of claim 8 , wherein the biasing member comprises a coil spring.

16. The system of claim 8 , wherein the first portion comprises an upper portion of each of the plurality of cover members.

17. The system of claim 8 , wherein the second portion comprises a sealing portion of each of the plurality of cover members.

18. The apparatus of claim 7 , wherein each of the first, second, and third helical conduits each comprises a dedicated outlet.

Assignees

• The Usa As Represented By The Sec Dep Of Health And Human Services
• The Usa As Represented By The Secretary Dept Of Health And Human Services

Inventors

• Godfrey Alexander Glenn
• Bende Pranav
• Wallgren Linus Eric
• Calabrese David

Classifications

• B01L3/563

  Joints or fittings; Separable fluid transfer means to transfer fluids between at least two containers, e.g. connectors · CPC title

• B01L3/56

  Labware specially adapted for transferring fluids · CPC title

• B01L3/50825

  Closing or opening means, corks, bungs · CPC title

• B01D1/30

  Accessories for evaporators {; Constructional details thereof} · CPC title

• G01N2001/4027

  evaporation leaving a concentrated sample · CPC title