Burdock seed oil-containing composition and method for producing same

Patent metadata

Field	Value
Publication number	US-12433926-B2
Application number	US-202519169459-A
Country	US
Kind code	B2
Filing date	Apr 3, 2025
Priority date	Oct 6, 2022
Publication date	Oct 7, 2025
Grant date	Oct 7, 2025

Abstract

The purpose of the present disclosure is to produce and provide a burdock seed oil-containing composition that is excellent in stability. The present disclosure relates to a composition containing (A) burdock seed oil and (B) triethyl citrate and containing 1 to 7.5 mass % of arctigenin derived from the component (A), and a method for producing the same.

First claim

The invention claimed is:

1. A composition comprising:
(A) burdock seed oil; and
(B) one or more compounds selected from the group consisting of triethyl citrate, diisopropyl adipate, diethyl sebacate, and phenoxyethanol;
wherein arctigenin derived from the component (A) has a content of 1 to 7.5 mass %, and
wherein the component (B) is the triethyl citrate.

2. The composition according to claim 1 , wherein the triethyl citrate has a content of 10 to 90 mass %.

3. A method for producing a composition, comprising blending (A) burdock seed oil and (B) one or more compounds selected from the group consisting of triethyl citrate, diisopropyl adipate, diethyl sebacate, and phenoxyethanol;
wherein the component (A) is blended so that a content of arctigenin derived from the component (A) is from 1 to 7.5 mass %, and
wherein the component (B) is the triethyl citrate.

4. A method for producing a composition, comprising:
blending (A) burdock seed oil and (B) one or more compounds selected from the group consisting of triethyl citrate, diisopropyl adipate, diethyl sebacate, and phenoxyethanol;
wherein arctigenin is included at a content of 2 to 15 mass % into the burdock seed oil.

5. The method for producing a composition according to claim 3 ,
wherein the triethyl citrate has a content of 10 to 90 mass %.

6. The method for producing a composition according to claim 4 ,
wherein the triethyl citrate has a content of 10 to 90 mass %.

7. A method for producing an external preparation or an oral preparation, comprising blending the composition according to claim 1 .

8. A method for producing an external preparation or an oral preparation, comprising blending the composition according to claim 2 .

Assignees

• Rohto Pharma

Inventors

• Imai Momoko
• Shimizu Takashi

Classifications

• A61K47/14

  Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters · CPC title

• A61K9/08

  Solutions {(composition of solutions A61K47/00)} · CPC title

• A61K36/28 Primary

  Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea · CPC title

• A61K47/10

  Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers · CPC title

• A61K31/365

  Lactones · CPC title