Method for reducing methane production in animal stomach

Patent metadata

Field	Value
Publication number	US-12427137-B2
Application number	US-202318104459-A
Country	US
Kind code	B2
Filing date	Feb 1, 2023
Priority date	Feb 11, 2022
Publication date	Sep 30, 2025
Grant date	Sep 30, 2025

Abstract

Provided is a method for reducing methane production in animal stomachs by adding melatonin to gastric juice of the animal or feeding the animal with melatonin. In the method of the present disclosure, 10-7 mol/L to 10-3 mol/L of melatonin can reduce the methane production from the in vitro gastric fermentation fluid, and feeding melatonin of 8.0 to 35.0 mg/kg/day can reduce the methane production from the animal respiration from day 7 of feeding melatonin. The method of the present disclosure can reduce greenhouse gas emissions of animals, control environmental pollution and realize low-carbon farming.

First claim

What is claimed is:

1. A process for reducing methane production in a stomach of a ruminant animal, comprising the following steps:
(1) adding melatonin in an amount of 10 −7 to 10 −3 mol/L to rumen fluids of the ruminant animal; or feeding the ruminant animal with melatonin in an amount of 12.0 to 35.0 mg/kg/day; and
(2) detecting the methane content in the breathing gas of the ruminant animal by gas chromatography.

2. The process according to claim 1 , wherein the melatonin is added to the rumen fluids in an amount of 10 −5 to 10 −3 mol/L.

3. The process according to claim 1 , wherein the melatonin is added to the rumen fluids in an amount of 103 mol/L.

4. The process according to claim 1 , wherein the animal is fed with melatonin in an amount of 15.0 to 25.0 mg/kg/day.

5. The process according to claim 1 , wherein the ruminant animal is fed with melatonin for 7 to 21 days.

6. The process according to claim 1 , wherein the ruminant animal is selected from the group consisting of cow, horse, sheep, camel and deer.

7. The process according to claim 6 , wherein the ruminant animal is cow.

Assignees

• Univ China Agricultural

Inventors

• Liu Guoshi
• Fu Yao
• Yao Songyang
• Ma Xiao
• Yu Haiying
• Yao Yujun
• Lv Dongying
• Guan Shengyu

Classifications

• A23K50/10

  for ruminants · CPC title

• A23K20/132

  containing only one nitrogen as hetero atom · CPC title

• Y02P60/22

  Methane [CH4], e.g. from rice paddies · CPC title

• A61K31/405

  Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin · CPC title

• A61K9/0056

  Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals · CPC title