Apparatuses, systems, and methods for sample testing

Patent metadata

Field	Value
Publication number	US-12422362-B2
Application number	US-202117447998-A
Country	US
Kind code	B2
Filing date	Sep 17, 2021
Priority date	May 7, 2020
Publication date	Sep 23, 2025
Grant date	Sep 23, 2025

Abstract

Methods, apparatuses, and systems associated with a sample testing device are provided. For example, an example sample testing device may include a substrate layer defining a bottom surface of the sample testing device, as well as a waveguide disposed on the substrate layer and includes at least one reference channel and at least one sample channel.

First claim

The invention claimed is:

1. A sample testing device comprising:
a waveguide comprising a plurality of flow channels;
a pump configured to deliver a buffer solution to a first flow channel of the plurality of flow channels through a first valve;
a first buffer loop connecting the first flow channel of the plurality of flow channels to a second flow channel of the plurality of flow channels through a second valve; and
a second buffer loop connecting the second flow channel of the plurality of flow channels to a third flow channel of the plurality of flow channels through a third valve, wherein a length of the first buffer loop is different from a length of the second buffer loop.

2. The sample testing device of claim 1 , wherein the first valve is a 2-configuration 6-port valve.

3. The sample testing device of claim 2 , wherein the first valve comprises a first port, a second port, a third port, a fourth port, a fifth port, and a sixth port, wherein the first valve is configured to provide a first configuration and a second configuration.

4. The sample testing device of claim 3 , wherein, when the first valve is in the first configuration, the fifth port of the first valve is connected to the sixth port of the first valve.

5. The sample testing device of claim 4 , wherein the pump is connected to the fifth port of the first valve.

6. The sample testing device of claim 5 , wherein the first flow channel is connected to the sixth port of the first valve.

7. The sample testing device of claim 6 , wherein, when the first valve is in the first configuration, the pump is configured to provide the buffer solution to the first flow channel through the first valve.

8. The sample testing device of claim 3 , wherein, when the first valve is in the first configuration, the first port of the first valve is connected to the second port of the first valve.

9. The sample testing device of claim 3 , wherein, when the first valve is in the first configuration, the third port of the first valve is connected to the fourth port of the first valve.

10. The sample testing device of claim 3 , wherein, when the first valve is in the second configuration, the first port of the first valve is connected to the sixth port of the first valve.

11. The sample testing device of claim 3 , wherein, when the first valve is in the second configuration, the third port of the first valve is connected to the second port of the first valve.

12. The sample testing device of claim 3 , wherein, when the first valve is in the second configuration, the fifth port of the first valve is connected to the fourth port of the first valve.

13. The sample testing device of claim 12 , wherein the fourth port of the first valve is connected to the first port of the first valve through a first sample loop.

14. The sample testing device of claim 13 , wherein, the first sample loop comprises a first fluid.

15. The sample testing device of claim 14 , when the first valve is in the second configuration, the pump is configured to inject the first fluid to the first flow channel.

16. The sample testing device of claim 14 , wherein the second valve is connected to the second flow channel of the plurality of flow channels of the waveguide.

17. The sample testing device of claim 16 , wherein the second valve is a 2-configuration 6-port valve.

18. The sample testing device of claim 17 , wherein the second valve comprises a second sample loop.

19. The sample testing device of claim 18 , wherein the second sample loop comprises a second fluid.

20. The sample testing device of claim 19 , wherein the pump is configured to inject the first fluid to the first flow channel and inject the second fluid to the second flow channel a same time.

Assignees

• Hand Held Prod Inc

Inventors

• Mcbrady Adam Dewey
• Feng Chen
• Shafai Moin
• Venkatarayalu Suresh

Classifications

• C23C2/51

  Computer-controlled implementation · CPC title

• C02F2209/006

  comprising a software program or a logic diagram · CPC title

• B29C2037/903

  by means of a computer · CPC title

• B23D63/008

  using computer control means · CPC title

• B01D2313/701

  comprising a software program or a logic diagram · CPC title