Respirator and ventilation control method therefor

Patent metadata

Field	Value
Publication number	US-12420044-B2
Application number	US-202017086544-A
Country	US
Kind code	B2
Filing date	Nov 2, 2020
Priority date	May 2, 2018
Publication date	Sep 23, 2025
Grant date	Sep 23, 2025

Abstract

The disclosure provides a respirator, which includes a ventilation device, configured for providing ventilation airflow to a patient. The respirator further includes a first monitor, configured for monitoring a pressure or a flow velocity with which the ventilation device ventilates the patient, and a second monitor, configured for measuring a pressure change that reflects a self-respiratory effort of the patient. The respirator also includes a processor, configured for identifying an inspiratory trigger moment or an expiratory trigger moment of the patient according to the pressure change that reflects the self-respiratory effort of the patient.

First claim

The invention claimed is:

1. A respirator, comprising:
a ventilation device, configured for providing a ventilation airflow to a patient;
a monitor, configured for measuring a pressure change at a body muscle of the patient other than an air passage of the patient that reflects a self-respiratory effort of the patient and measuring a pressure waveform that reflects the self-respiratory effort of the patient using a pressure sensor; and
a processor, configured for identifying an inspiratory trigger moment and an expiratory trigger moment of the patient according to the pressure change at the body muscle of the patient other than the air passage of the patient that reflects the self-respiratory effort of the patient, wherein the inspiratory trigger moment is a first time point in a timeline where a first expiratory phase is switched to an inspiratory phase, and the expiratory trigger moment is a second time point in the timeline where the inspiratory phase is switch to a second expiratory phase,
wherein the processor is further configured for:
controlling the ventilation device to switch from the first expiratory phase to the inspiratory phase, when the second expiratory trigger moment is identified;
controlling the ventilation device to switch from the inspiratory phase to the expiratory phase, when the expiratory trigger moment is identified;
extracting an envelope from the pressure waveform that reflects the self-respiratory effort of the patient;
determining a peak and a trough of the envelope; and
identifying the inspiratory trigger moment of the patient as the moment when the envelope is at the peak and identifying the expiratory trigger moment of the patient as the moment when the envelope is at the trough.

2. The respirator of claim 1 , wherein
the pressure change comprises one or more of an esophageal pressure change or an intragastric pressure change.

3. The respirator of claim 1 , wherein the processor is further configured for
outputting the inspiratory trigger moment and the expiratory trigger moment to a display module, after the inspiratory trigger moment and the expiratory trigger moment are identified.

4. The respirator of claim 1 , wherein the processor is further configured for computing patient-respirator synchronization information, after the inspiratory trigger moment and the expiratory trigger moment are identified.

5. The respirator of claim 1 , wherein the processor is configured for determining a single peak and a single trough of the envelope for each inspiration phase and each expiration phase.

6. The respirator of claim 1 , wherein the processor is configured for:
acquiring a plurality of inspiratory trigger moments and a plurality of expiratory trigger moments;
calculating a difference value between an inspiratory trigger moment and an expiratory trigger moment that are adjacent in the timeline, and acquiring a patient inspiration time and a patient expiration time, wherein when the expiratory trigger moment is later than the inspiratory trigger moment, the calculated difference value is the patient inspiration time, and when the inspiratory trigger moment is later than the expiratory trigger moment, the calculated difference value is the patient expiration time;
calculating a machine inspiration time and a machine expiration time of the respirator;
calculating an inspiratory time difference between the patient inspiration time and the machine inspiration time and an expiratory time difference between the patient expiration time and the machine expiration time; and
when the inspiratory time difference and the expiratory time difference both are less than or equal to a threshold, determining that the respirator is synchronous with the patient; and when at least one of the inspiratory time difference or the expiratory time difference is greater than the threshold, determining that the respirator is asynchronous with the patient.

7. A ventilation control method for a respirator, comprising:
providing a ventilation airflow to a patient by using a ventilation device;
measuring a pressure or a flow velocity of the ventilation airflow provided by the ventilation device to the patient using a pressure sensor or a flow sensor, respectively;
measuring a pressure change at a body muscle of the patient other than an air passage of the patient that reflects a self-respiratory effort of the patient;
measuring a pressure waveform that reflects the self-respiratory effort of the patient according to the measured pressure change using the pressure sensor;
controlling the ventilation device to switch from a first expiratory phase to an inspiratory phase, when an inspiratory trigger moment of the patient is identified;
controlling the ventilation device to switch from the inspiratory phase to a second expiratory phase, when an expiratory trigger moment of the patient is identified;
extracting an envelope from the pressure waveform that reflects the self-respiratory effort of the patient;
determining a peak and a trough of the envelope; and
identifying the inspiratory trigger moment of the patient as the moment when the envelope is at the peak and identifying an expiratory trigger moment of the patient as the moment when the envelope is at the trough, wherein the inspiratory trigger moment is a first time point in a timeline where the first expiratory phase is switched to the inspiratory phase, and the expiratory trigger moment is a second time point in the timeline where the inspiratory phase is switched to the second expiratory phase.

8. The ventilation control method of claim 7 , wherein
the pressure change comprises one or more of an esophageal pressure change or an intragastric pressure change.

9. The ventilation control method of claim 7 , wherein after the inspiratory trigger moment and the expiratory trigger moment are identified, the ventilation control method further comprises:
outputting the inspiratory trigger moment and the expiratory trigger moment to a display module.

10. The ventilation control method of claim 7 , wherein after the inspiratory trigger moment and the expiratory trigger moment are identified, the ventilation control method further comprises:
computing patient-respirator synchronization information.

Assignees

• Shenzhen Mindray Biomedical Electronics Co Ltd
• Zhongda Hospital Southeast Univ

Inventors

• Liu Ling
• Liu Jinglei
• Yang Yi
• Zhou Xiaoyong
• Pan Chun
• Yan Yongsheng
• Xie Jianfeng
• Liu Songqiao
• Qiu Haibo

Classifications

• A61M2210/105

  Oesophagus · CPC title

• A61M2205/50

  with microprocessors or computers · CPC title

• A61M2205/3344

  Measuring or controlling pressure at the body treatment site · CPC title

• A61M2016/003

  with a flowmeter · CPC title

• A61M2016/0027

  pressure meter · CPC title