Readily dissolvable steviol glycoside compositions

Patent metadata

Field	Value
Publication number	US-12419335-B2
Application number	US-202318335946-A
Country	US
Kind code	B2
Filing date	Jun 15, 2023
Priority date	Oct 6, 2017
Publication date	Sep 23, 2025
Grant date	Sep 23, 2025

Abstract

A readily dissolvable steviol glycoside composition comprising a steviol glycoside and a dissolution enhancer compound in an amount effective to increase dissolution of the steviol glycoside.

First claim

The invention claimed is:

1. A method for preparing a steviol glycoside solution, the method comprising:
adding to an aqueous solution crystalline rebaudioside M; one or more dicaffeoylquinic acids or salts thereof; and one or more monocaffeoylquinic acids or salts thereof to form the steviol glycoside solution,
wherein rebaudioside M is at least 70% by weight of total steviol glycosides in the steviol glycoside solution; and
wherein dissolution of rebaudioside M at room temperature is faster than dissolution of rebaudioside M alone without the one or more dicaffeoylquinic acids or salts thereof and without the one or more monocaffeoylquinic acids or salts thereof, such that when the crystalline rebaudioside M; one or more dicaffeoylquinic acids or salts thereof; and one or more monocaffeoylquinic acids or salts thereof added to an aqueous solution to form a 3000 ppm steviol glycoside solution, the rebaudioside M is completely dissolved in less than 15 minutes.

2. The method of claim 1 , wherein the ratio of total steviol glycosides to total of monocaffeoylquinic acids or salts and dicaffeoylquinic acids and salts is between 1:0.3 to 1:3 in the steviol glycoside solution.

3. The method of claim 1 , wherein the ratio of total steviol glycosides to total of monocaffeoylquinic acids or salts and dicaffeoylquinic acids and salts is between 1:1 to 1:3 in the steviol glycoside solution.

4. The method of claim 1 , wherein the one or more dicaffeoylquinic acids or salts thereof comprise one or more of 1,3-dicaffeoylquinic acid, 1,4-dicaffeoylquinic acid, 1,5-dicaffeoylquinic acid, 3,4-dicaffeoylquinic acid, 3,5-dicaffeoylquinic acid, 4,5-dicaffeoylquinic acid, and salts thereof.

5. The method of claim 1 , wherein the one or more monocaffeoylquinic acids or salts thereof comprise one or more of 3-O-caffeoylquinic acid, 4-O-caffeoylquinic acid, 5-O-caffeoylquinic acid, and salts thereof.

6. The method of claim 1 , wherein the total steviol glycosides comprises rebaudioside D.

7. The method of claim 1 , wherein the total steviol glycosides comprises rebaudioside A.

8. The method of claim 1 , wherein the total steviol glycosides, the one or more dicaffeoylquinic acid or salt thereof and the one or more monocaffeoylquinic acid or salt thereof are co-dried prior to addition to the aqueous solution.

9. The method of claim 1 , wherein the one or more dicaffeoylquinic acids or salts thereof and the one or more monocaffeoylquinic acids or salts thereof are prepared from a botanical source.

10. The method of claim 9 , wherein the botanical source is yerba mate.

11. The method of claim 9 , wherein the botanical source is stevia.

12. The method of claim 1 , wherein the total of monocaffeoylquinic acids or salts and dicaffeoylquinic acids and salts comprises at least 15% dicaffeoylquinic acids and salts thereof.

13. The method of claim 1 , wherein at least one of 3-O-feruloylquinic acid, 4-O-feruloylquinic acid, 5-O-feruloylquinic acid, 3,4-diferuloylquinic acid, 3,5-diferuloylquinic acid, or 4,5-diferuloylquinic acid is also added to the aqueous solution.

14. The method of claim 1 , wherein the aqueous solution comprises less than 1% C1-C4 alcohols.

15. The method of claim 1 , wherein the aqueous solution is substantially free of C1-C4 alcohols.

16. The method of claim 1 , wherein the total steviol glycosides, dicaffeoylquinic acids or salts thereof, and monocaffeoylquinic acids or salts thereof are added to the aqueous solution at a temperature less than 30° C., the total steviol glycoside concentration is at least 5 wt % in the steviol glycoside solution, and the rebaudioside M completely dissolves in less than 10 seconds.

17. The method of claim 1 , wherein the final concentration of steviol glycoside in the steviol glycoside solution is between 3000 ppm and 60000 ppm.

18. The method of claim 1 , wherein total steviol glycoside in the steviol glycoside solution comprises less than 1 wt % of rebaudioside A.

19. The method of claim 1 , wherein total steviol glycoside in the steviol glycoside solution comprises less than 1 wt % rebaudioside A, at least 80 wt % rebaudioside M, and between 10 wt % and 20 wt % rebaudioside D.

Assignees

• Cargill Inc

Inventors

• Gaspard Dan S
• Zarth Adam T

Classifications

• B01D15/361

  Ion-exchange · CPC title

• A61K2236/39

  Complex extraction schemes, e.g. fractionation or repeated extraction steps · CPC title

• A61K2236/31

  involving untreated material, e.g. fruit juice or sap obtained from fresh plants · CPC title

• A61K31/235

  having an aromatic ring attached to a carboxyl group · CPC title

• A61K31/192

  having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid  {(cannabinoids A61K31/658)} · CPC title